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The map label for this gene is fecD [C]

Identifier: 218710605

GI number: 218710605

Start: 2846047

End: 2847111

Strand: Direct

Name: fecD [C]

Synonym: VS_2658

Alternate gene names: 218710605

Gene position: 2846047-2847111 (Clockwise)

Preceding gene: 218710604

Following gene: 218710606

Centisome position: 86.26

GC content: 44.79

Gene sequence:

>1065_bases
CTGCAATTGAAAAATTGGCACAGCGCATCCAAGAAATACATGACAAGTCTTAGTACTAACCTGAACCGAACCGCACTGAA
CACCTGCGTATTCAGTTCTGTTTTTGCCCTCTTAGCGATGTTTTCTCTGAGTTTGGGCAGCGTTCAGCTATCTTTTGCAC
AAGTCGCTACGATTTTTTCAGCTGCGATGAGTCAACAGATCGACTCACCGATAGATCAAGTGGTACTGCACCTGCGCTTA
CCTAGAACAATCATCGCTATTATTTGCGGTGCTGGGTTAGGTATTGTTGGGGCGTTATTACAAACCGTGACAAAAAACGA
TCTTGCCGACCCTTTCATTTTTGGATTGTCATCCGGTGCCGCAACTGGAGCAGTCTTTGTGATTACAGTCATCGGCAGCG
CTATCGGCATTTGGACACTTCCACTCGCCGCTTTTATCGGTGGAATAATCTCGGCTTCGGCAGTGCTATTTCTAGTCAGA
AAAGTAGATGGACAAGCGTCTTCTCAAATTGTTTTAGCCGGGTTAGCTATTTCATTTTTATTTACAGCCTTGACTAACTT
CTTGGTCTTCCATGGTGATCAACGAGCTGCCCATTCGATTCTATTTTGGTCGCTAGGAGGCCTAGGAAACGCACGCTGGG
ACAATGTGCTAATTGTGCTTGCTGGACTTATCGTCTTGATAGCCCTAGGTATATTAAAACATCGCCAGTTAGATTGTTTA
CTTGCAGGAGACGACGTAGCACAAACCATGGGCGTAGACACAAAACGCCTGCAAAGCGGTGTCTTTATTGTCTGCGCTTT
TGCAACTGCATGTTTTGTTTCTATCATCGGAGTTGTCGGATTTATTGGCTTGATGGTTCCTCATATCGCGAAGAAAATCA
TCGGCCCATTACACAAAAAGTTACTCATCACTTCAGGGCTGATTGGGGCTTTGCTTATGCTATTAAGTGATATTTTGGCG
AGAACCTTAGTTGCTCCTCAAGAACTGCCTCTTGGTGTTGTCACCACCGCGTTTGGCGCACTATTCATTGTTTCCATTTT
GATGGAGAAAAGTAATGAAAGCTGA

Upstream 100 bases:

>100_bases
TTGGAACAGCACCCAGCGATGAAGCTGACCACAGCGGTAAAGACCACCCAATACCTTCCTCTGCGTTATGAGGAAATTAC
TCCCGGGCCAGCAAACATAG

Downstream 100 bases:

>100_bases
ACGCTTCACCATCATTGCGATTCGTCATGGCGAAACCGAATGGAATCGAATAGGCAAAGCACAGAATCAACTGGATAGCC
CTCTGACAATGAAAGGCAAA

Product: ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MQLKNWHSASKKYMTSLSTNLNRTALNTCVFSSVFALLAMFSLSLGSVQLSFAQVATIFSAAMSQQIDSPIDQVVLHLRL
PRTIIAIICGAGLGIVGALLQTVTKNDLADPFIFGLSSGAATGAVFVITVIGSAIGIWTLPLAAFIGGIISASAVLFLVR
KVDGQASSQIVLAGLAISFLFTALTNFLVFHGDQRAAHSILFWSLGGLGNARWDNVLIVLAGLIVLIALGILKHRQLDCL
LAGDDVAQTMGVDTKRLQSGVFIVCAFATACFVSIIGVVGFIGLMVPHIAKKIIGPLHKKLLITSGLIGALLMLLSDILA
RTLVAPQELPLGVVTTAFGALFIVSILMEKSNES

Sequences:

>Translated_354_residues
MQLKNWHSASKKYMTSLSTNLNRTALNTCVFSSVFALLAMFSLSLGSVQLSFAQVATIFSAAMSQQIDSPIDQVVLHLRL
PRTIIAIICGAGLGIVGALLQTVTKNDLADPFIFGLSSGAATGAVFVITVIGSAIGIWTLPLAAFIGGIISASAVLFLVR
KVDGQASSQIVLAGLAISFLFTALTNFLVFHGDQRAAHSILFWSLGGLGNARWDNVLIVLAGLIVLIALGILKHRQLDCL
LAGDDVAQTMGVDTKRLQSGVFIVCAFATACFVSIIGVVGFIGLMVPHIAKKIIGPLHKKLLITSGLIGALLMLLSDILA
RTLVAPQELPLGVVTTAFGALFIVSILMEKSNES
>Mature_354_residues
MQLKNWHSASKKYMTSLSTNLNRTALNTCVFSSVFALLAMFSLSLGSVQLSFAQVATIFSAAMSQQIDSPIDQVVLHLRL
PRTIIAIICGAGLGIVGALLQTVTKNDLADPFIFGLSSGAATGAVFVITVIGSAIGIWTLPLAAFIGGIISASAVLFLVR
KVDGQASSQIVLAGLAISFLFTALTNFLVFHGDQRAAHSILFWSLGGLGNARWDNVLIVLAGLIVLIALGILKHRQLDCL
LAGDDVAQTMGVDTKRLQSGVFIVCAFATACFVSIIGVVGFIGLMVPHIAKKIIGPLHKKLLITSGLIGALLMLLSDILA
RTLVAPQELPLGVVTTAFGALFIVSILMEKSNES

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=31.5112540192926, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1790741, Length=323, Percent_Identity=32.1981424148607, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786804, Length=336, Percent_Identity=29.1666666666667, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786347, Length=309, Percent_Identity=30.0970873786408, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788004, Length=295, Percent_Identity=29.8305084745763, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786805, Length=302, Percent_Identity=31.1258278145695, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37243; Mature: 37243

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKNWHSASKKYMTSLSTNLNRTALNTCVFSSVFALLAMFSLSLGSVQLSFAQVATIFS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AAMSQQIDSPIDQVVLHLRLPRTIIAIICGAGLGIVGALLQTVTKNDLADPFIFGLSSGA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
ATGAVFVITVIGSAIGIWTLPLAAFIGGIISASAVLFLVRKVDGQASSQIVLAGLAISFL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FTALTNFLVFHGDQRAAHSILFWSLGGLGNARWDNVLIVLAGLIVLIALGILKHRQLDCL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
LAGDDVAQTMGVDTKRLQSGVFIVCAFATACFVSIIGVVGFIGLMVPHIAKKIIGPLHKK
ECCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLITSGLIGALLMLLSDILARTLVAPQELPLGVVTTAFGALFIVSILMEKSNES
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLKNWHSASKKYMTSLSTNLNRTALNTCVFSSVFALLAMFSLSLGSVQLSFAQVATIFS
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
AAMSQQIDSPIDQVVLHLRLPRTIIAIICGAGLGIVGALLQTVTKNDLADPFIFGLSSGA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHCCCCCC
ATGAVFVITVIGSAIGIWTLPLAAFIGGIISASAVLFLVRKVDGQASSQIVLAGLAISFL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FTALTNFLVFHGDQRAAHSILFWSLGGLGNARWDNVLIVLAGLIVLIALGILKHRQLDCL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
LAGDDVAQTMGVDTKRLQSGVFIVCAFATACFVSIIGVVGFIGLMVPHIAKKIIGPLHKK
ECCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLITSGLIGALLMLLSDILARTLVAPQELPLGVVTTAFGALFIVSILMEKSNES
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]