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The map label for this gene is glmM [H]

Identifier: 218710476

GI number: 218710476

Start: 2699124

End: 2700536

Strand: Direct

Name: glmM [H]

Synonym: VS_2515

Alternate gene names: 218710476

Gene position: 2699124-2700536 (Clockwise)

Preceding gene: 218710475

Following gene: 218710486

Centisome position: 81.81

GC content: 44.16

Gene sequence:

>1413_bases
ATGATTAAATTTGGTACAGGTGGCTGGCGCGCTTTCATTGGTGAAGAGTTCACCAGAGACAATGTTCGCCTTGTAGCGCA
AGCGCTCGCTAACATCATCAATAATGAAGATGCAGCCAAGAATGGCTTCGTTATTGGCTATGACCGTCGCTTCCTTTCAG
ATAAAGCGGCATGCTGGTTTGCAGAAGTACTTGCGGCGAACAACATCAAAGTAAGCTTCATTGATAAGTTCGTTCCAACA
CCTATCGTGATGTTCCAAGCAAAAGAGATGGGATGTATTTACTCTGCGTGTATTACCGCTTCTCACAACCCAGCGGACTA
TAACGGCATAAAGATCTTCATTGAAGGTGGACGCGATGCTGACGAGATCATCACAGAGAAGATCGAACAGCAAATCGCAA
CACTGACCAACGAAGATGTTATACGAGTCGATTTTGAACAAGCGTTAAACGACAAAGAAATCGAGATCATCAACCCGATG
AACGACTTTGTTGATTCAATCATCAACTTCATCGATATCGATTCGATTAAGAAAGCCAACCTGCGCGTACTGATTGATCC
AATGTTTGGTGTTGCGAAAAATGCTCTGCAAACCGTACTGATCAACGGTCGCTGTGATGTCGACGTAATCAACGATGGTA
AGAACCCAGATTTCGGCGGTCTTATGCCGTCCCCAAATGCAGCAACGCTATACCGCCTAAAACATTTAGTGGCAGCTGAA
GGCTATGACATTGGTATTGGTACTGATGGCGATGCCGACCGTTTAGGCATCATTGATGAGAAAGGTCACTTTATTCATCC
TAACGAAGTGCTACTACTACTTTACTACTACTTACTGGAATACAAAGGCTGGAAGGGCTCTGTCGTTCGTAACATCGCCA
CCACGCATCTACTCGACAAAGTAGCGGCAGATCATGGTGAGAAGAGCTTTGAGGTTCCTGTAGGCTTTAAGCATATCAGC
TCTCAAATGGAAGCAGATGATTCACTGATTGGTGGTGAAAGCTCGGGAGGTTTAACCATTCGAGGTCATATCAAAGGTAA
GGATGGCGTATTTGCTTCAAGCTTACTGGTTGAGATGATCAGTGTAACAGGTAAAAAGTTATCTGAGTTACTTGATGAAA
TCTACTCTAAGTATGGCTATGCCTACACGGCAGAAGGAGATTGCCAGTTTAAGCCTTCAGAGAAAGAAGCGCTCTACACC
AAGATTTACGTAGAGAAGCAACTGCCTGAATTTGAATACGAAATTGAAAAAGTTAGCTATGAAGATGGTGCCAAAGTGTA
CTTCAAGAATGGCGGATGGGTCATTGCTCGCTTCTCCGGAACAGAGCCGTTACTGCGAATCTTCGCAGAAATGGAAGATA
AAGACACTGCAGAACGTGTTCTTCAAAAAGTGAAAGACTTCCTCTCTCTATAG

Upstream 100 bases:

>100_bases
ACGATGTTGTCGTTGTTCTAGGCTAGTCACTTAATTTAACGAACAGCTCTTGCCTCAAGTCTTTATCGACTTGAGGCAAT
GAGACTAAAAGGATTTTCTA

Downstream 100 bases:

>100_bases
ATTTATAGAGTGCAGCAGTTTTGAATGGGACTTAACAAACCACTGCCTTGTTAAAGCCTGTAGGTGAAGAACTCTTGCCC
AGTACTCTGTATCAAAGTGC

Product: putative phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIKFGTGGWRAFIGEEFTRDNVRLVAQALANIINNEDAAKNGFVIGYDRRFLSDKAACWFAEVLAANNIKVSFIDKFVPT
PIVMFQAKEMGCIYSACITASHNPADYNGIKIFIEGGRDADEIITEKIEQQIATLTNEDVIRVDFEQALNDKEIEIINPM
NDFVDSIINFIDIDSIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPNAATLYRLKHLVAAE
GYDIGIGTDGDADRLGIIDEKGHFIHPNEVLLLLYYYLLEYKGWKGSVVRNIATTHLLDKVAADHGEKSFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLDEIYSKYGYAYTAEGDCQFKPSEKEALYT
KIYVEKQLPEFEYEIEKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKDTAERVLQKVKDFLSL

Sequences:

>Translated_470_residues
MIKFGTGGWRAFIGEEFTRDNVRLVAQALANIINNEDAAKNGFVIGYDRRFLSDKAACWFAEVLAANNIKVSFIDKFVPT
PIVMFQAKEMGCIYSACITASHNPADYNGIKIFIEGGRDADEIITEKIEQQIATLTNEDVIRVDFEQALNDKEIEIINPM
NDFVDSIINFIDIDSIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPNAATLYRLKHLVAAE
GYDIGIGTDGDADRLGIIDEKGHFIHPNEVLLLLYYYLLEYKGWKGSVVRNIATTHLLDKVAADHGEKSFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLDEIYSKYGYAYTAEGDCQFKPSEKEALYT
KIYVEKQLPEFEYEIEKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKDTAERVLQKVKDFLSL
>Mature_470_residues
MIKFGTGGWRAFIGEEFTRDNVRLVAQALANIINNEDAAKNGFVIGYDRRFLSDKAACWFAEVLAANNIKVSFIDKFVPT
PIVMFQAKEMGCIYSACITASHNPADYNGIKIFIEGGRDADEIITEKIEQQIATLTNEDVIRVDFEQALNDKEIEIINPM
NDFVDSIINFIDIDSIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPNAATLYRLKHLVAAE
GYDIGIGTDGDADRLGIIDEKGHFIHPNEVLLLLYYYLLEYKGWKGSVVRNIATTHLLDKVAADHGEKSFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSELLDEIYSKYGYAYTAEGDCQFKPSEKEALYT
KIYVEKQLPEFEYEIEKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKDTAERVLQKVKDFLSL

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=488, Percent_Identity=25.4098360655738, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI290463102, Length=488, Percent_Identity=25.4098360655738, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI133922562, Length=514, Percent_Identity=24.5136186770428, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI31377548, Length=548, Percent_Identity=25.9124087591241, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI290463104, Length=311, Percent_Identity=25.7234726688103, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI63055049, Length=526, Percent_Identity=22.8136882129278, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786904, Length=487, Percent_Identity=26.2833675564682, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788361, Length=451, Percent_Identity=24.8337028824834, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789566, Length=481, Percent_Identity=23.0769230769231, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17535441, Length=498, Percent_Identity=25.7028112449799, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71993870, Length=537, Percent_Identity=22.3463687150838, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71993878, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323752, Length=536, Percent_Identity=26.865671641791, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322722, Length=428, Percent_Identity=26.6355140186916, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323934, Length=407, Percent_Identity=24.3243243243243, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864244, Length=499, Percent_Identity=28.0561122244489, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI20129809, Length=524, Percent_Identity=26.1450381679389, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24651977, Length=422, Percent_Identity=26.5402843601896, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24653722, Length=372, Percent_Identity=24.4623655913978, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 52348; Mature: 52348

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKFGTGGWRAFIGEEFTRDNVRLVAQALANIINNEDAAKNGFVIGYDRRFLSDKAACWF
CCEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHCCHHHHHH
AEVLAANNIKVSFIDKFVPTPIVMFQAKEMGCIYSACITASHNPADYNGIKIFIEGGRDA
HHHHHCCCCEEEEEHHHCCCCEEEEECHHCCHHHHHHHCCCCCCCCCCCEEEEEECCCCH
DEIITEKIEQQIATLTNEDVIRVDFEQALNDKEIEIINPMNDFVDSIINFIDIDSIKKAN
HHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCC
LRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPNAATLYRLKHLVAAE
EEEEECCHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GYDIGIGTDGDADRLGIIDEKGHFIHPNEVLLLLYYYLLEYKGWKGSVVRNIATTHLLDK
CEEEECCCCCCCCCCCEEECCCCEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAADHGEKSFEVPVGFKHISSQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMI
HHHHCCCCCEECCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SVTGKKLSELLDEIYSKYGYAYTAEGDCQFKPSEKEALYTKIYVEKQLPEFEYEIEKVSY
HHHHHHHHHHHHHHHHHHCEEEECCCCCEECCCCHHHEEEEEEEECCCCCHHHHHHEECC
EDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKDTAERVLQKVKDFLSL
CCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKFGTGGWRAFIGEEFTRDNVRLVAQALANIINNEDAAKNGFVIGYDRRFLSDKAACWF
CCEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHCCHHHHHH
AEVLAANNIKVSFIDKFVPTPIVMFQAKEMGCIYSACITASHNPADYNGIKIFIEGGRDA
HHHHHCCCCEEEEEHHHCCCCEEEEECHHCCHHHHHHHCCCCCCCCCCCEEEEEECCCCH
DEIITEKIEQQIATLTNEDVIRVDFEQALNDKEIEIINPMNDFVDSIINFIDIDSIKKAN
HHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCC
LRVLIDPMFGVAKNALQTVLINGRCDVDVINDGKNPDFGGLMPSPNAATLYRLKHLVAAE
EEEEECCHHHHHHHHHHEEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GYDIGIGTDGDADRLGIIDEKGHFIHPNEVLLLLYYYLLEYKGWKGSVVRNIATTHLLDK
CEEEECCCCCCCCCCCEEECCCCEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAADHGEKSFEVPVGFKHISSQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMI
HHHHCCCCCEECCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SVTGKKLSELLDEIYSKYGYAYTAEGDCQFKPSEKEALYTKIYVEKQLPEFEYEIEKVSY
HHHHHHHHHHHHHHHHHHCEEEECCCCCEECCCCHHHEEEEEEEECCCCCHHHHHHEECC
EDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKDTAERVLQKVKDFLSL
CCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]