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The map label for this gene is erpA

Identifier: 218710462

GI number: 218710462

Start: 2677088

End: 2677462

Strand: Reverse

Name: erpA

Synonym: VS_2501

Alternate gene names: 218710462

Gene position: 2677462-2677088 (Counterclockwise)

Preceding gene: 218710477

Following gene: 218710461

Centisome position: 81.15

GC content: 45.87

Gene sequence:

>375_bases
ATGTTGTTTTTGACACAGGTAAGAGAGGTTGTCGTGAGCGAAGTAAATATCCCATTGTCCTTTTCTGATGCAGCAGCTAC
CCGCGTACAAACGCTAATTGCTGAAGAAGAAAACCCAGATCTAAAACTGCGTGTATACATTACAGGCGGCGGTTGTAGTG
GCTTCCAGTACGGCTTCACATTTGATGAAAAAGTAAATGATGGCGACACTACCATTGTAAATAGCGGTGTGACGCTGGTT
GTTGACCCAATGAGCCTACAGTACTTAATGGGCGGCATGGTTGATTACACTGAAGGCCTAGAAGGCGCACGTTTCTTTGT
GAACAACCCGAACGCGACAACAACATGTGGTTGTGGCGCATCATTTAGCGTTTAG

Upstream 100 bases:

>100_bases
GATCCTGTGGTGAATACTTGAACGTTTCAGTCAGGTATTAGATAATCACCAGAATATAAGAAAATACTCAACAACTATGG
TCTCGATTTAGATTTGTATC

Downstream 100 bases:

>100_bases
CGTTTAGCGTGCACTGAAAGGTAGCTTGAACGGAAAGCTACATTAGAAATATTTTAAACGCCGAGCCAATGCTCGGTGTT
TTTGTTTGTAAAAAATACAC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MLFLTQVREVVVSEVNIPLSFSDAAATRVQTLIAEEENPDLKLRVYITGGGCSGFQYGFTFDEKVNDGDTTIVNSGVTLV
VDPMSLQYLMGGMVDYTEGLEGARFFVNNPNATTTCGCGASFSV

Sequences:

>Translated_124_residues
MLFLTQVREVVVSEVNIPLSFSDAAATRVQTLIAEEENPDLKLRVYITGGGCSGFQYGFTFDEKVNDGDTTIVNSGVTLV
VDPMSLQYLMGGMVDYTEGLEGARFFVNNPNATTTCGCGASFSV
>Mature_124_residues
MLFLTQVREVVVSEVNIPLSFSDAAATRVQTLIAEEENPDLKLRVYITGGGCSGFQYGFTFDEKVNDGDTTIVNSGVTLV
VDPMSLQYLMGGMVDYTEGLEGARFFVNNPNATTTCGCGASFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=97, Percent_Identity=42.2680412371134, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=27.3584905660377, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=73.8738738738739, Blast_Score=180, Evalue=3e-47,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=40, Blast_Score=69, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=38.8888888888889, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=26.5486725663717, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=27.3584905660377, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=32.0754716981132, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=45.7831325301205, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=33.6448598130841, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_VIBSL (B7VJJ4)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418083.1
- ProteinModelPortal:   B7VJJ4
- GeneID:   7162035
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2501
- HOGENOM:   HBG730174
- OMA:   TNINEND
- ProtClustDB:   PRK13623
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13322; Mature: 13322

Theoretical pI: Translated: 3.87; Mature: 3.87

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLTQVREVVVSEVNIPLSFSDAAATRVQTLIAEEENPDLKLRVYITGGGCSGFQYGFT
CEEHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCE
FDEKVNDGDTTIVNSGVTLVVDPMSLQYLMGGMVDYTEGLEGARFFVNNPNATTTCGCGA
ECCCCCCCCCEEEECCCEEEECCCHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEECCCC
SFSV
CCCC
>Mature Secondary Structure
MLFLTQVREVVVSEVNIPLSFSDAAATRVQTLIAEEENPDLKLRVYITGGGCSGFQYGFT
CEEHHHHHHHHHHHCCCCEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCE
FDEKVNDGDTTIVNSGVTLVVDPMSLQYLMGGMVDYTEGLEGARFFVNNPNATTTCGCGA
ECCCCCCCCCEEEECCCEEEECCCHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEECCCC
SFSV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA