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The map label for this gene is nlpI [H]

Identifier: 218710440

GI number: 218710440

Start: 2648034

End: 2648957

Strand: Reverse

Name: nlpI [H]

Synonym: VS_2477

Alternate gene names: 218710440

Gene position: 2648957-2648034 (Counterclockwise)

Preceding gene: 218710441

Following gene: 218710439

Centisome position: 80.29

GC content: 45.02

Gene sequence:

>924_bases
GTGAAATGGTTTCAAACCGCGAGTATGTGTTTACTGCTTGTACTGACAGGTTGTGCGACAACATCAGATAACACCTCACG
TTGGGTTTATCCACCAATGGCTGTGCCGCTGCAACCAAGCGTTCAGCAAGAGGTTCAAATTGCACGTCTTAGTCAATTAT
TACAGCGCCCGGACTTGAATGATGAAGTTCGATCTAAGATGCTGTTTGAACGTGGTAACTACTACGATAGTGTTGGCCTG
CGTGATCTAGCACGTCTCGACTTCAACCAATCTCTTTCATTGAACCCTGCTCAACCTGATATCTTCAACCTTTTGGGGGT
TTACTTTACGCAGGTAGGGGAGTTTGATGCGGCTTATGAATCTTTTGATTCTACGTTAGAGCTTGATCCTGCAAACTCTT
ACGCAGAAAGAAACCGCTCTATCGCACTCTACTACGGCGAACGTTATGATTTAGCCAATGAAGAGATGACGAAGCATTAT
ACCGATGACCCAAGTGATCCATTCCGTGCGCTTTGGTTGTATATCATTCAGCACGAACTCACGCCAGAGCAAGCCAAGCT
TGATTTGCAAAAACGTTACGAGAGCCGTGATGAGCAGTGGGGTTGGGTATTAGTCGCGATTATGCTTGATGACATTACTG
AAGAGCAGGCTTTTAAGGCCATCTTGACCGGTACTCGTGACAACACGTTACTTGCGCAGCGCCTAACTGAGACATATTTC
TACCTTGCTAAGCGTTACCACATGAATGGGGACTACGCGAATGCGATCTCTCTGTACAAGTTGTCAGTGTCTTTCAATGT
GTATGAATATGTAGAGCATCGTTACTCTTTCTTAGAGCTAAGCCGTATATTTACTACTCTTAAAGCCGAGCACTTAGCAA
AAGTTAAGTTGGCTGAGGCCGAAGAAAAAGCCGACACAAAGTAA

Upstream 100 bases:

>100_bases
CGCTTTTTAGTGATTTCTAACCCATTGGTAAAAAAGCATGTTATAAAGGGGAGCATATCGCTCCCCTTTTTTATTGCGGT
CATAACAGGAGTAATTATTT

Downstream 100 bases:

>100_bases
ACGATATATTTTGATTCCGAACAACCGCTGCCTGTCAGCGGTTTTTTTATGTTCCTTTTTTATGCTCCTTTTTTATAAAC
AGGTGGGGGGGGGGGGGGGC

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKWFQTASMCLLLVLTGCATTSDNTSRWVYPPMAVPLQPSVQQEVQIARLSQLLQRPDLNDEVRSKMLFERGNYYDSVGL
RDLARLDFNQSLSLNPAQPDIFNLLGVYFTQVGEFDAAYESFDSTLELDPANSYAERNRSIALYYGERYDLANEEMTKHY
TDDPSDPFRALWLYIIQHELTPEQAKLDLQKRYESRDEQWGWVLVAIMLDDITEEQAFKAILTGTRDNTLLAQRLTETYF
YLAKRYHMNGDYANAISLYKLSVSFNVYEYVEHRYSFLELSRIFTTLKAEHLAKVKLAEAEEKADTK

Sequences:

>Translated_307_residues
MKWFQTASMCLLLVLTGCATTSDNTSRWVYPPMAVPLQPSVQQEVQIARLSQLLQRPDLNDEVRSKMLFERGNYYDSVGL
RDLARLDFNQSLSLNPAQPDIFNLLGVYFTQVGEFDAAYESFDSTLELDPANSYAERNRSIALYYGERYDLANEEMTKHY
TDDPSDPFRALWLYIIQHELTPEQAKLDLQKRYESRDEQWGWVLVAIMLDDITEEQAFKAILTGTRDNTLLAQRLTETYF
YLAKRYHMNGDYANAISLYKLSVSFNVYEYVEHRYSFLELSRIFTTLKAEHLAKVKLAEAEEKADTK
>Mature_307_residues
MKWFQTASMCLLLVLTGCATTSDNTSRWVYPPMAVPLQPSVQQEVQIARLSQLLQRPDLNDEVRSKMLFERGNYYDSVGL
RDLARLDFNQSLSLNPAQPDIFNLLGVYFTQVGEFDAAYESFDSTLELDPANSYAERNRSIALYYGERYDLANEEMTKHY
TDDPSDPFRALWLYIIQHELTPEQAKLDLQKRYESRDEQWGWVLVAIMLDDITEEQAFKAILTGTRDNTLLAQRLTETYF
YLAKRYHMNGDYANAISLYKLSVSFNVYEYVEHRYSFLELSRIFTTLKAEHLAKVKLAEAEEKADTK

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=282, Percent_Identity=49.290780141844, Blast_Score=271, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 35701; Mature: 35701

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFQTASMCLLLVLTGCATTSDNTSRWVYPPMAVPLQPSVQQEVQIARLSQLLQRPDLN
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
DEVRSKMLFERGNYYDSVGLRDLARLDFNQSLSLNPAQPDIFNLLGVYFTQVGEFDAAYE
HHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
SFDSTLELDPANSYAERNRSIALYYGERYDLANEEMTKHYTDDPSDPFRALWLYIIQHEL
HHCCCEEECCCHHHHHCCCCEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHC
TPEQAKLDLQKRYESRDEQWGWVLVAIMLDDITEEQAFKAILTGTRDNTLLAQRLTETYF
CHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YLAKRYHMNGDYANAISLYKLSVSFNVYEYVEHRYSFLELSRIFTTLKAEHLAKVKLAEA
HHHHHHCCCCCHHCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEKADTK
HHCCCCC
>Mature Secondary Structure
MKWFQTASMCLLLVLTGCATTSDNTSRWVYPPMAVPLQPSVQQEVQIARLSQLLQRPDLN
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
DEVRSKMLFERGNYYDSVGLRDLARLDFNQSLSLNPAQPDIFNLLGVYFTQVGEFDAAYE
HHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
SFDSTLELDPANSYAERNRSIALYYGERYDLANEEMTKHYTDDPSDPFRALWLYIIQHEL
HHCCCEEECCCHHHHHCCCCEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHC
TPEQAKLDLQKRYESRDEQWGWVLVAIMLDDITEEQAFKAILTGTRDNTLLAQRLTETYF
CHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YLAKRYHMNGDYANAISLYKLSVSFNVYEYVEHRYSFLELSRIFTTLKAEHLAKVKLAEA
HHHHHHCCCCCHHCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEKADTK
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]