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The map label for this gene is serB [H]

Identifier: 218710421

GI number: 218710421

Start: 2628466

End: 2629446

Strand: Reverse

Name: serB [H]

Synonym: VS_2458

Alternate gene names: 218710421

Gene position: 2629446-2628466 (Counterclockwise)

Preceding gene: 218710423

Following gene: 218710419

Centisome position: 79.7

GC content: 46.48

Gene sequence:

>981_bases
ATGGACGCTCAGAAATATCTGCCGATTAAAAGGCATACGACATTATTAACCCGACTCCCCGAGACACGTTTCGCTTCTCA
ACTCGCAAAATCTAAAGCCAATTGGATTGTGTTCGGTGAGTACTTATCTCCACAATCATTTGATGACATCGACTTTTTCA
CTGGTACCTACAACACCATCCTCAATACGTGGAAGGTGGGACATTACGAAGTGGCACTGATGTCAGGGAACTTAACCCCG
GCACACGAAGAAATTTTACAAGCACTGAAGCTTGATTATGCTTGCCTTAGCGAGGTCCCAGACTTATCTAAGCCAGGTTT
GATCGTGATGGATATGGACTCCACAGCAATTCAAATTGAATGCATCGATGAGATAGCAAAGCTCGCAGGAGTCGGAGAGT
TAGTTTCTGAAATCACAGAGCGTGCGATGCAAGGCGAGCTCGACTTTGAACAGAGCCTACGCCAACGCGTTGGGGCACTG
AAAGGTGCGGATGAGTCGATACTGGAGCAAGTGCGCCAGTCATTACCATTCATGCCAGACTTGGTTGAGCTAGTGAATAC
TCTGAATAAACTTGGCTGGAAGACGGCGATTGCATCGGGTGGTTTTACTTATTTCTCAGACTACCTGAAAGATACGCTTG
ATCTTGACCACGCTCAGTCAAACACGCTAGAGATCGTCAATGGTAAATTGACGGGTGAAGTATTAGGCGATGTTGTTTCC
GCACAGACCAAAGCGGATATCTTGGTAGAACTTGCTGAAGAGTATGAACTGGAACTGCATAACACCGTTGCCGTGGGTGA
TGGTGCCAATGACTTGGTTATGATGGGTTCTGCCGGTTTAGGGATTGCTTACCATGCAAAACCGAAAGTTGAACAACAAG
CTCAAACTGCTGTGCGTTATGCTGGCTTAGGTGGGGTGCTTTGTATCTTGTCAGGTGTATTAGCTAAGCAGCAAAAAATT
AGCTGGCAAGCGAAGCCTTAG

Upstream 100 bases:

>100_bases
AGCCTGAAATAAACAAATGTTATGATTAAGACATATTGAGACTTGCGTTTTCAAATTGCAATAGGTTAACGTTTAGCATA
GTTAATTAGGAATCATACAC

Downstream 100 bases:

>100_bases
TCATATTTAGGGCGGTATAACGGATACAAAAAAGCAGGTGATGAGCCTGCTTTTTCTATTTTTAAATCCGATAAATCTAC
AAACCGGTAAGTTGATCTGG

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MDAQKYLPIKRHTTLLTRLPETRFASQLAKSKANWIVFGEYLSPQSFDDIDFFTGTYNTILNTWKVGHYEVALMSGNLTP
AHEEILQALKLDYACLSEVPDLSKPGLIVMDMDSTAIQIECIDEIAKLAGVGELVSEITERAMQGELDFEQSLRQRVGAL
KGADESILEQVRQSLPFMPDLVELVNTLNKLGWKTAIASGGFTYFSDYLKDTLDLDHAQSNTLEIVNGKLTGEVLGDVVS
AQTKADILVELAEEYELELHNTVAVGDGANDLVMMGSAGLGIAYHAKPKVEQQAQTAVRYAGLGGVLCILSGVLAKQQKI
SWQAKP

Sequences:

>Translated_326_residues
MDAQKYLPIKRHTTLLTRLPETRFASQLAKSKANWIVFGEYLSPQSFDDIDFFTGTYNTILNTWKVGHYEVALMSGNLTP
AHEEILQALKLDYACLSEVPDLSKPGLIVMDMDSTAIQIECIDEIAKLAGVGELVSEITERAMQGELDFEQSLRQRVGAL
KGADESILEQVRQSLPFMPDLVELVNTLNKLGWKTAIASGGFTYFSDYLKDTLDLDHAQSNTLEIVNGKLTGEVLGDVVS
AQTKADILVELAEEYELELHNTVAVGDGANDLVMMGSAGLGIAYHAKPKVEQQAQTAVRYAGLGGVLCILSGVLAKQQKI
SWQAKP
>Mature_326_residues
MDAQKYLPIKRHTTLLTRLPETRFASQLAKSKANWIVFGEYLSPQSFDDIDFFTGTYNTILNTWKVGHYEVALMSGNLTP
AHEEILQALKLDYACLSEVPDLSKPGLIVMDMDSTAIQIECIDEIAKLAGVGELVSEITERAMQGELDFEQSLRQRVGAL
KGADESILEQVRQSLPFMPDLVELVNTLNKLGWKTAIASGGFTYFSDYLKDTLDLDHAQSNTLEIVNGKLTGEVLGDVVS
AQTKADILVELAEEYELELHNTVAVGDGANDLVMMGSAGLGIAYHAKPKVEQQAQTAVRYAGLGGVLCILSGVLAKQQKI
SWQAKP

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=170, Percent_Identity=28.8235294117647, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790849, Length=286, Percent_Identity=55.2447552447552, Blast_Score=321, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI115534456, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534454, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=44.1747572815534, Blast_Score=166, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35710; Mature: 35710

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAQKYLPIKRHTTLLTRLPETRFASQLAKSKANWIVFGEYLSPQSFDDIDFFTGTYNTI
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHCCHHHHH
LNTWKVGHYEVALMSGNLTPAHEEILQALKLDYACLSEVPDLSKPGLIVMDMDSTAIQIE
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHH
CIDEIAKLAGVGELVSEITERAMQGELDFEQSLRQRVGALKGADESILEQVRQSLPFMPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHH
LVELVNTLNKLGWKTAIASGGFTYFSDYLKDTLDLDHAQSNTLEIVNGKLTGEVLGDVVS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHH
AQTKADILVELAEEYELELHNTVAVGDGANDLVMMGSAGLGIAYHAKPKVEQQAQTAVRY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHH
AGLGGVLCILSGVLAKQQKISWQAKP
HCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDAQKYLPIKRHTTLLTRLPETRFASQLAKSKANWIVFGEYLSPQSFDDIDFFTGTYNTI
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHCCHHHHH
LNTWKVGHYEVALMSGNLTPAHEEILQALKLDYACLSEVPDLSKPGLIVMDMDSTAIQIE
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHH
CIDEIAKLAGVGELVSEITERAMQGELDFEQSLRQRVGALKGADESILEQVRQSLPFMPD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHH
LVELVNTLNKLGWKTAIASGGFTYFSDYLKDTLDLDHAQSNTLEIVNGKLTGEVLGDVVS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHH
AQTKADILVELAEEYELELHNTVAVGDGANDLVMMGSAGLGIAYHAKPKVEQQAQTAVRY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHH
AGLGGVLCILSGVLAKQQKISWQAKP
HCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]