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The map label for this gene is cph2 [H]

Identifier: 218710356

GI number: 218710356

Start: 2560015

End: 2561580

Strand: Direct

Name: cph2 [H]

Synonym: VS_2392

Alternate gene names: 218710356

Gene position: 2560015-2561580 (Clockwise)

Preceding gene: 218710355

Following gene: 218710357

Centisome position: 77.59

GC content: 43.49

Gene sequence:

>1566_bases
ATGGGCATTCTTGAAAAAGACATTCAGGCGCAACTCCACCAGCTGAAATATCAGTTGGATCAAGTCCGCTTGACGCAAAG
AGATACCTCGTTCAAATTTATTCGAGAACAAAAAGTTCTCAAGCGTATCGTTACGTCTTTAAGTGATGCATGTGTTGGCA
GCAACACTCATTTAGATGAAAACCTCATTGCCCTTAGGGAAGAGCTCGAAAAGCAAAAAGACATTAGCTCAATGATCCCC
AAGTTGGCAGTATTAGAAAGGATGCTCAAGCAAAAAACGTTGGCTATGGATAAACAGAACGGATATCTGGATGATAGTAT
TAAGCACAGTGGGGAAACGCTGCAGCGTATAACTGGCCTTCCGGCACAGCTAAAGCGCGATCTAAGAAACTTACTTAGCT
TCTCCGAGTGTCATGGCAGTCAAAAAGTCGACCATGCCATGAAGCTTCTCAGCATTTATGAGCGTGCCATTAAGATTATG
GCAAACAACTCACGCACTCATTTTGCCGACGTAGATCAATCAACTGAACAAGAACTCCTTTCCGAACTATCAAACGAATT
ACAACACCTGATCACTGAACTCGACTTCGAGGGTGAATCGGGGGATCTACTGACCGATATTCGAGCGAAGCTACTACTTG
GTGTTTCAACACAAAACCTACTTGAGCTAGCACTTCAGATCCTCAAACTGGTGATTGATGGCACGAGCCTAGAGCGTAAG
CAGTCTGAACAATTTATCGAACAACTCAATTCCTCGCTCGCTTCTAGTATCAAAACAGCAGATCAAAACTCCGACCAGAG
CCAAAGCTATTTTGAACATCGCCAAGGTCTTAATTCGGAGTTGAATGAACTTGTTACTAAGAGCCAAAGCTCTGTTGATA
AAGCAACGGATATTGATAACTTAAAACTTTCGATAAACCCGCTGCTCAGTGAAATTGCCTCTCTTTCAGAAAGACTGAAT
CACGCAGAACAGAAAGAACAAGCTCTAATAGAAAGAATGAGCTACGGAAAAAACCAATTAGATTCGCTCTATGAAGTCAC
CCAAGATTACCGCAAGCGTCTAGAAGATCAGGCTCAGCGTATGCTGCTTGACCCTCTGACTAAGATCTACAACCGTACCG
CCTTCACCGATCGTTTAGAGTTAGAATATCGTCGCTGGATTCGCGCACAACACTCACTAAGAGTCGTGCTGCTAGATATC
GATAACTTCAAAGCAATTAACGATAGCTTTGGCTATACCGCTGGTGACAAAGCACTCAAGATCATCGCAAGAGCCATCAC
CAAAGAAATTGGTACTACCGATACTGTCGCTCGCTTTTCTGGTGAAGAGTTCATCTTGCTACTTCCCGAGCAAAGCGATG
AATATTGCCATCAAGTGACTCAAAGCATCCAGAATCAAGTCAGCCGCTTACCTTTCAAATTCCGTGACCAACAAATCACA
ATTACCTTGTGCGCGGCAAGTACTCCGTTTAAAGAGTCAGACACACCTGAAGAAGTATTAGAGCGACTCAATAAAACACT
AAACAAAGCCAAACAGCGCGGTAACAACCAACTTGTTTGGGACTAA

Upstream 100 bases:

>100_bases
TCGTAGGTCGTGACCTTATTTTTAGTTTTGTTATTATCAAGGTCACGGAATTTCATCTATACGATCGAGTACGATCTACG
CGGCGCTAATTAATACACCT

Downstream 100 bases:

>100_bases
GACAGCCCTAGATTTAATTTATTTCATTTTTTCAAATACTTATCACATACCATATCCCTCAATGTTTGCTAAGCTAATGA
TTAACATTCGCTTAACAATC

Product: GGDEF family protein

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MGILEKDIQAQLHQLKYQLDQVRLTQRDTSFKFIREQKVLKRIVTSLSDACVGSNTHLDENLIALREELEKQKDISSMIP
KLAVLERMLKQKTLAMDKQNGYLDDSIKHSGETLQRITGLPAQLKRDLRNLLSFSECHGSQKVDHAMKLLSIYERAIKIM
ANNSRTHFADVDQSTEQELLSELSNELQHLITELDFEGESGDLLTDIRAKLLLGVSTQNLLELALQILKLVIDGTSLERK
QSEQFIEQLNSSLASSIKTADQNSDQSQSYFEHRQGLNSELNELVTKSQSSVDKATDIDNLKLSINPLLSEIASLSERLN
HAEQKEQALIERMSYGKNQLDSLYEVTQDYRKRLEDQAQRMLLDPLTKIYNRTAFTDRLELEYRRWIRAQHSLRVVLLDI
DNFKAINDSFGYTAGDKALKIIARAITKEIGTTDTVARFSGEEFILLLPEQSDEYCHQVTQSIQNQVSRLPFKFRDQQIT
ITLCAASTPFKESDTPEEVLERLNKTLNKAKQRGNNQLVWD

Sequences:

>Translated_521_residues
MGILEKDIQAQLHQLKYQLDQVRLTQRDTSFKFIREQKVLKRIVTSLSDACVGSNTHLDENLIALREELEKQKDISSMIP
KLAVLERMLKQKTLAMDKQNGYLDDSIKHSGETLQRITGLPAQLKRDLRNLLSFSECHGSQKVDHAMKLLSIYERAIKIM
ANNSRTHFADVDQSTEQELLSELSNELQHLITELDFEGESGDLLTDIRAKLLLGVSTQNLLELALQILKLVIDGTSLERK
QSEQFIEQLNSSLASSIKTADQNSDQSQSYFEHRQGLNSELNELVTKSQSSVDKATDIDNLKLSINPLLSEIASLSERLN
HAEQKEQALIERMSYGKNQLDSLYEVTQDYRKRLEDQAQRMLLDPLTKIYNRTAFTDRLELEYRRWIRAQHSLRVVLLDI
DNFKAINDSFGYTAGDKALKIIARAITKEIGTTDTVARFSGEEFILLLPEQSDEYCHQVTQSIQNQVSRLPFKFRDQQIT
ITLCAASTPFKESDTPEEVLERLNKTLNKAKQRGNNQLVWD
>Mature_520_residues
GILEKDIQAQLHQLKYQLDQVRLTQRDTSFKFIREQKVLKRIVTSLSDACVGSNTHLDENLIALREELEKQKDISSMIPK
LAVLERMLKQKTLAMDKQNGYLDDSIKHSGETLQRITGLPAQLKRDLRNLLSFSECHGSQKVDHAMKLLSIYERAIKIMA
NNSRTHFADVDQSTEQELLSELSNELQHLITELDFEGESGDLLTDIRAKLLLGVSTQNLLELALQILKLVIDGTSLERKQ
SEQFIEQLNSSLASSIKTADQNSDQSQSYFEHRQGLNSELNELVTKSQSSVDKATDIDNLKLSINPLLSEIASLSERLNH
AEQKEQALIERMSYGKNQLDSLYEVTQDYRKRLEDQAQRMLLDPLTKIYNRTAFTDRLELEYRRWIRAQHSLRVVLLDID
NFKAINDSFGYTAGDKALKIIARAITKEIGTTDTVARFSGEEFILLLPEQSDEYCHQVTQSIQNQVSRLPFKFRDQQITI
TLCAASTPFKESDTPEEVLERLNKTLNKAKQRGNNQLVWD

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=32.5, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=28.75, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787802, Length=130, Percent_Identity=34.6153846153846, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081881, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=26.6233766233766, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788956, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=26.1627906976744, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787816, Length=129, Percent_Identity=28.6821705426357, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788381, Length=113, Percent_Identity=34.5132743362832, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 59656; Mature: 59525

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILEKDIQAQLHQLKYQLDQVRLTQRDTSFKFIREQKVLKRIVTSLSDACVGSNTHLDE
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NLIALREELEKQKDISSMIPKLAVLERMLKQKTLAMDKQNGYLDDSIKHSGETLQRITGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
PAQLKRDLRNLLSFSECHGSQKVDHAMKLLSIYERAIKIMANNSRTHFADVDQSTEQELL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SELSNELQHLITELDFEGESGDLLTDIRAKLLLGVSTQNLLELALQILKLVIDGTSLERK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH
QSEQFIEQLNSSLASSIKTADQNSDQSQSYFEHRQGLNSELNELVTKSQSSVDKATDIDN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
LKLSINPLLSEIASLSERLNHAEQKEQALIERMSYGKNQLDSLYEVTQDYRKRLEDQAQR
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MLLDPLTKIYNRTAFTDRLELEYRRWIRAQHSLRVVLLDIDNFKAINDSFGYTAGDKALK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
IIARAITKEIGTTDTVARFSGEEFILLLPEQSDEYCHQVTQSIQNQVSRLPFKFRDQQIT
HHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCCEEE
ITLCAASTPFKESDTPEEVLERLNKTLNKAKQRGNNQLVWD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GILEKDIQAQLHQLKYQLDQVRLTQRDTSFKFIREQKVLKRIVTSLSDACVGSNTHLDE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NLIALREELEKQKDISSMIPKLAVLERMLKQKTLAMDKQNGYLDDSIKHSGETLQRITGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
PAQLKRDLRNLLSFSECHGSQKVDHAMKLLSIYERAIKIMANNSRTHFADVDQSTEQELL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SELSNELQHLITELDFEGESGDLLTDIRAKLLLGVSTQNLLELALQILKLVIDGTSLERK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH
QSEQFIEQLNSSLASSIKTADQNSDQSQSYFEHRQGLNSELNELVTKSQSSVDKATDIDN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
LKLSINPLLSEIASLSERLNHAEQKEQALIERMSYGKNQLDSLYEVTQDYRKRLEDQAQR
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MLLDPLTKIYNRTAFTDRLELEYRRWIRAQHSLRVVLLDIDNFKAINDSFGYTAGDKALK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHH
IIARAITKEIGTTDTVARFSGEEFILLLPEQSDEYCHQVTQSIQNQVSRLPFKFRDQQIT
HHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCEECCCEEE
ITLCAASTPFKESDTPEEVLERLNKTLNKAKQRGNNQLVWD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]