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The map label for this gene is insF7 [C]

Identifier: 218710350

GI number: 218710350

Start: 2553573

End: 2554280

Strand: Direct

Name: insF7 [C]

Synonym: VS_2386

Alternate gene names: 218710350

Gene position: 2553573-2554280 (Clockwise)

Preceding gene: 218710349

Following gene: 218710354

Centisome position: 77.4

GC content: 43.08

Gene sequence:

>708_bases
GTGCTCGGTTTTGTGAAGGAGCAAAGGATGATGCACCCTCGAATAGGGGCTCGTAAGATCAAGTATTTACTTGCTCAGAA
CGATATTGAAATCGGGCGAGACCGCTTATTCTCTCTGCTGAGAGTGAATCGATTATTAGTACAGAATCGAAGGGCTTACC
ATCGAACCACAAACAGTAATCATCGCTTTTACTGCCATCCAAATCGAATCAAAGAAGGCTTAATACCGGAAGGACCGGAG
CAATTATGGGTTGCCGATATTACTTATCTAGCAACGCGGCGTGGTAGTACTTATCTCAGTTTAGTGACGGACGCTTACTC
AAGAAAAATCGTGGGCTATCACATAAGTGATGATATGAAAGCTCACACGGTCAAGCAGGCCTTTTTAAACGCGCTGAAAG
GGCGGAAGAATACAGGTGAGCTTGTCCATCACTCAGATAGAGGTGTTCAGTACTGCTCTGTTGAATACCAAGAGTTGCAT
CGACAGTATGGTGTATCTTGCTCAATGACTGATGGCTATGACTGTTATCAGAATGCGTTGGCAGAGAGGGTCAACGGAAT
ATTGAAGATGGAGTATCTGTTGAATAAGCCTAATGATTTAGATGAAGCAAAGAAAATGGTCGCTGAATCAGTAAAAATCT
ATAATGAATATAGGCCTCACACAGCTCTAAAATACAAAACGCCCGATGAAGTACATCGAGCGTTTTAG

Upstream 100 bases:

>100_bases
GTTGACCGTCACCAAAGCTTGTCACTTCATAGGTATTACACGACAAGCTTTCTACAAGCGCTGTGTTGCAGAAATTCATC
AGACAAAGAAAGATGAATCT

Downstream 100 bases:

>100_bases
TCAATCAAGTGTCAACCCATATCAGGACGGGTCATTATTCTTCTATCATCGCCTGTAGTATGGGTTTTATTGAAAGAGCT
GTTTCTACATGATCAGTATC

Product: ISVisp4 transposase OrfB

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPE
QLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQAFLNALKGRKNTGELVHHSDRGVQYCSVEYQELH
RQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMVAESVKIYNEYRPHTALKYKTPDEVHRAF

Sequences:

>Translated_235_residues
MLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPE
QLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQAFLNALKGRKNTGELVHHSDRGVQYCSVEYQELH
RQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMVAESVKIYNEYRPHTALKYKTPDEVHRAF
>Mature_235_residues
MLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSNHRFYCHPNRIKEGLIPEGPE
QLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMKAHTVKQAFLNALKGRKNTGELVHHSDRGVQYCSVEYQELH
RQYGVSCSMTDGYDCYQNALAERVNGILKMEYLLNKPNDLDEAKKMVAESVKIYNEYRPHTALKYKTPDEVHRAF

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=182, Percent_Identity=34.6153846153846, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1788405, Length=193, Percent_Identity=30.5699481865285, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787263, Length=193, Percent_Identity=30.5699481865285, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786753, Length=193, Percent_Identity=30.5699481865285, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786570, Length=193, Percent_Identity=30.5699481865285, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786490, Length=193, Percent_Identity=30.5699481865285, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789981, Length=165, Percent_Identity=30.9090909090909, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 27439; Mature: 27439

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSN
CCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
HRFYCHPNRIKEGLIPEGPEQLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMK
CEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHH
AHTVKQAFLNALKGRKNTGELVHHSDRGVQYCSVEYQELHRQYGVSCSMTDGYDCYQNAL
HHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEHHHHHHHHHHCCEECCCCCHHHHHHHH
AERVNGILKMEYLLNKPNDLDEAKKMVAESVKIYNEYRPHTALKYKTPDEVHRAF
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCC
>Mature Secondary Structure
MLGFVKEQRMMHPRIGARKIKYLLAQNDIEIGRDRLFSLLRVNRLLVQNRRAYHRTTNSN
CCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
HRFYCHPNRIKEGLIPEGPEQLWVADITYLATRRGSTYLSLVTDAYSRKIVGYHISDDMK
CEEEECHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHH
AHTVKQAFLNALKGRKNTGELVHHSDRGVQYCSVEYQELHRQYGVSCSMTDGYDCYQNAL
HHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEHHHHHHHHHHCCEECCCCCHHHHHHHH
AERVNGILKMEYLLNKPNDLDEAKKMVAESVKIYNEYRPHTALKYKTPDEVHRAF
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]