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The map label for this gene is metI [H]

Identifier: 218710347

GI number: 218710347

Start: 2551379

End: 2552062

Strand: Direct

Name: metI [H]

Synonym: VS_2383

Alternate gene names: 218710347

Gene position: 2551379-2552062 (Clockwise)

Preceding gene: 218710346

Following gene: 218710348

Centisome position: 77.33

GC content: 46.78

Gene sequence:

>684_bases
ATGTCCTTTAGTTTCAACGAAATTGCTGACTGGATCAGCCTTAACGGCAACCTTCTATTGGAAGCAACAGGCGAGACACT
TTACATGGTTGCAGTTGCTGGCATCGTTGGTTTCGCTGTCGGTATTCCATTAGGCGTTATTCTACACACGACTAAAAAAG
GTGGGCTGTTAGAGAACACCAAGCTAAACAAAATTCTTGGTGCGATTGTGAACGTGGGCCGTTCTGTGCCTTTCTTAGTA
CTGATGGTAGCGATCATCCCTCTCACTAAGATGCTGATTGGTACCTTCATCGGTACAACCGCAGCGATTGTTCCGCTGAC
GATTGGTGCTATCCCATTCGTAGCTCGACTTATCGAGAGTGCACTACTTGAAGTACCAACAGGTCTAGTGGAAGCAGCTC
AGTCAATGGGCGCAACACCAACACAAATCATCAATAAGGTTCTGCTTCCTGAAGCACTGCCGACTATCATCAACTCAGTG
ACGATTACGCTAGTAACTCTTGTGAGTTACTCGGCAATGGCCGGAACTGTGGGTGGTGGTGGCCTAGGTGATGTCGCGAT
TCGTTACGGATTTCACCGCTACGATGTGACCATTATGGCAGTAACAGTCGTCATGTTGATTGTGCTAGTACAAATTATTC
AATCAATCGGTGATTCATTAGTTCGCCGCGTTGACCACAGATAA

Upstream 100 bases:

>100_bases
TTCGGCATGATGGTCGCTGAGCTGTTCGGTAACGAAGCCGATGATAATGCTGCTATCCAATTCCTACGCGACAACAATGT
AAAAGTAGAGGTGCTTGGTT

Downstream 100 bases:

>100_bases
CGACTCAGCGTTAAAACGCAAACTATCTAAGACAAGAGTCGTCTGAACCAAATTAAATAGATTTATTAAAAGGAGATTAT
TATGAAATTTAACCTTAAAG

Product: putative D-methionine transport system permease MetI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSFSFNEIADWISLNGNLLLEATGETLYMVAVAGIVGFAVGIPLGVILHTTKKGGLLENTKLNKILGAIVNVGRSVPFLV
LMVAIIPLTKMLIGTFIGTTAAIVPLTIGAIPFVARLIESALLEVPTGLVEAAQSMGATPTQIINKVLLPEALPTIINSV
TITLVTLVSYSAMAGTVGGGGLGDVAIRYGFHRYDVTIMAVTVVMLIVLVQIIQSIGDSLVRRVDHR

Sequences:

>Translated_227_residues
MSFSFNEIADWISLNGNLLLEATGETLYMVAVAGIVGFAVGIPLGVILHTTKKGGLLENTKLNKILGAIVNVGRSVPFLV
LMVAIIPLTKMLIGTFIGTTAAIVPLTIGAIPFVARLIESALLEVPTGLVEAAQSMGATPTQIINKVLLPEALPTIINSV
TITLVTLVSYSAMAGTVGGGGLGDVAIRYGFHRYDVTIMAVTVVMLIVLVQIIQSIGDSLVRRVDHR
>Mature_226_residues
SFSFNEIADWISLNGNLLLEATGETLYMVAVAGIVGFAVGIPLGVILHTTKKGGLLENTKLNKILGAIVNVGRSVPFLVL
MVAIIPLTKMLIGTFIGTTAAIVPLTIGAIPFVARLIESALLEVPTGLVEAAQSMGATPTQIINKVLLPEALPTIINSVT
ITLVTLVSYSAMAGTVGGGGLGDVAIRYGFHRYDVTIMAVTVVMLIVLVQIIQSIGDSLVRRVDHR

Specific function: Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=210, Percent_Identity=53.3333333333333, Blast_Score=200, Evalue=7e-53,
Organism=Escherichia coli, GI1789033, Length=192, Percent_Identity=31.7708333333333, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23832; Mature: 23701

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSFNEIADWISLNGNLLLEATGETLYMVAVAGIVGFAVGIPLGVILHTTKKGGLLENT
CCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHH
KLNKILGAIVNVGRSVPFLVLMVAIIPLTKMLIGTFIGTTAAIVPLTIGAIPFVARLIES
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLEVPTGLVEAAQSMGATPTQIINKVLLPEALPTIINSVTITLVTLVSYSAMAGTVGGG
HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLGDVAIRYGFHRYDVTIMAVTVVMLIVLVQIIQSIGDSLVRRVDHR
CHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFSFNEIADWISLNGNLLLEATGETLYMVAVAGIVGFAVGIPLGVILHTTKKGGLLENT
CCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHH
KLNKILGAIVNVGRSVPFLVLMVAIIPLTKMLIGTFIGTTAAIVPLTIGAIPFVARLIES
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLEVPTGLVEAAQSMGATPTQIINKVLLPEALPTIINSVTITLVTLVSYSAMAGTVGGG
HHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLGDVAIRYGFHRYDVTIMAVTVVMLIVLVQIIQSIGDSLVRRVDHR
CHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]