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The map label for this gene is wrbA [H]

Identifier: 218710279

GI number: 218710279

Start: 2480113

End: 2480706

Strand: Direct

Name: wrbA [H]

Synonym: VS_2313

Alternate gene names: 218710279

Gene position: 2480113-2480706 (Clockwise)

Preceding gene: 218710278

Following gene: 218710280

Centisome position: 75.17

GC content: 49.49

Gene sequence:

>594_bases
ATGAGCATCAACATTCTTGTTCTCTACTATAGTCGACACGGCAACACCCAAGCGCTAGCAAGGCAAATCGCTCGTGGGGT
GGAATCCATCCCGAACTGCGAAGCCATGCTAAGAACGGTGAACAACGTGTATACGGTAGAAGAGCAGCCGGATTCGCGCT
ATCAGCCAACAGATCCTATTGCGACCTTACAAGATCTCCGTTCTTGCGACGGTTTAGCACTCGGCAGCCCAGTATGGTTT
GGCAATATGGCTGGGCCAATGAAGCACTTTTGGGATAGCACAACATCGTTATGGATTAATGGCGATCTCATCGATAAACC
AGCTTGTGTATTTACTTCCTCTTCATCACTACACGGTGGTCAAGAGACGACACAGCAAAGCATGATGCTGCCTCTACTTC
ATCATGGCATGTTAGTCGTGGGCATCCCCTATTCAGAACCTGCACTGCACACCACTCAAACCGGTGGCACACCTTACGGT
GCAAGCAGCACTGGAGAGAGCGCTTCATTAAGCAAAGAAGAAATTGAGTTGGCGAAAAACCTAGGCAAACGCGTAGCGCG
CATCGCTATTAACCAGAAGGGAATGCCTCAATGA

Upstream 100 bases:

>100_bases
AACGAATCCAAAACTGTTTGAACGTCCAGTGGTTGTCGCGAACAACAAAGCAAAAATTGGTCGTCCACCAGAACAAGTAC
TAGAGATTCTGTAATCCAAT

Downstream 100 bases:

>100_bases
TGTATATGTCAGAGAGACCGATGTCTCCCAAAACCAAGCTATTTCGCTACCTTGCTTTAACGGGCAATTTGTCGCTTTTA
TTCTGGGTGGTTGCTTGGCA

Product: multimeric flavodoxin WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSINILVLYYSRHGNTQALARQIARGVESIPNCEAMLRTVNNVYTVEEQPDSRYQPTDPIATLQDLRSCDGLALGSPVWF
GNMAGPMKHFWDSTTSLWINGDLIDKPACVFTSSSSLHGGQETTQQSMMLPLLHHGMLVVGIPYSEPALHTTQTGGTPYG
ASSTGESASLSKEEIELAKNLGKRVARIAINQKGMPQ

Sequences:

>Translated_197_residues
MSINILVLYYSRHGNTQALARQIARGVESIPNCEAMLRTVNNVYTVEEQPDSRYQPTDPIATLQDLRSCDGLALGSPVWF
GNMAGPMKHFWDSTTSLWINGDLIDKPACVFTSSSSLHGGQETTQQSMMLPLLHHGMLVVGIPYSEPALHTTQTGGTPYG
ASSTGESASLSKEEIELAKNLGKRVARIAINQKGMPQ
>Mature_196_residues
SINILVLYYSRHGNTQALARQIARGVESIPNCEAMLRTVNNVYTVEEQPDSRYQPTDPIATLQDLRSCDGLALGSPVWFG
NMAGPMKHFWDSTTSLWINGDLIDKPACVFTSSSSLHGGQETTQQSMMLPLLHHGMLVVGIPYSEPALHTTQTGGTPYGA
SSTGESASLSKEEIELAKNLGKRVARIAINQKGMPQ

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=198, Percent_Identity=37.8787878787879, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319849, Length=200, Percent_Identity=32.5, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320235, Length=186, Percent_Identity=30.1075268817204, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 21419; Mature: 21287

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINILVLYYSRHGNTQALARQIARGVESIPNCEAMLRTVNNVYTVEEQPDSRYQPTDPI
CCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHH
ATLQDLRSCDGLALGSPVWFGNMAGPMKHFWDSTTSLWINGDLIDKPACVFTSSSSLHGG
HHHHHHHHCCCCCCCCCEEECCCCCHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCC
QETTQQSMMLPLLHHGMLVVGIPYSEPALHTTQTGGTPYGASSTGESASLSKEEIELAKN
HHHHHHHHHHHHHHCCEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LGKRVARIAINQKGMPQ
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SINILVLYYSRHGNTQALARQIARGVESIPNCEAMLRTVNNVYTVEEQPDSRYQPTDPI
CEEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHH
ATLQDLRSCDGLALGSPVWFGNMAGPMKHFWDSTTSLWINGDLIDKPACVFTSSSSLHGG
HHHHHHHHCCCCCCCCCEEECCCCCHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCC
QETTQQSMMLPLLHHGMLVVGIPYSEPALHTTQTGGTPYGASSTGESASLSKEEIELAKN
HHHHHHHHHHHHHHCCEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LGKRVARIAINQKGMPQ
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA