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The map label for this gene is acrE [H]

Identifier: 218710083

GI number: 218710083

Start: 2260049

End: 2261212

Strand: Reverse

Name: acrE [H]

Synonym: VS_2104

Alternate gene names: 218710083

Gene position: 2261212-2260049 (Counterclockwise)

Preceding gene: 218710085

Following gene: 218710082

Centisome position: 68.54

GC content: 47.94

Gene sequence:

>1164_bases
TTGGTTAGTCTAAAAAAAAACATAATTGAGTACCGCATAGGAACAGTACGTATGTATAAATTGATGAAGGGAAGCGCAGT
GGCAGTGGCGTTGTCGGCTTTTCTTGTTGGATGTGGCGAAAAGGAACAAGCCCAAGAGTCGGTTGATTCAACAGCTGAAA
CGGCATCGAGCGTCCAAACCATTTTAACGGTGGAAACGATGGCCTTGGCGCTGTCTTCCTCTTATGCAGTTCAGCGTGAA
TATGTCGGTGTGGTTAAGGCGGGTCAGCAGGCTAATTTAGGTTTCGAACTGGCCGGAAAAGTAAACGAGATTCTGGTGGA
TGTCGGTGACACAGTCACAACGGGTCAGCCGTTGATCAGACTGGATAACCAACTTTTGGAAACCGAGTCTAGCCAACTGA
AAGCGCAGGCTGAAGAAGTCAAAGCTCAATTGAGTTTGGTGGCTGCGAACCTTAAACGTCAACGTTCATTGAAAGCGAAA
GGCTTCAGTGCCGAAGCTGAGATTGATTCGTTAACCAGTGAGCAACGCGTATTGCAGGCGAACTTGCTGCGTATTGATGC
CTCGGTAAAAGGCAATCAATTGAAGTTGGTGAAATCGACAGTTCGTGCGCCATATTCAGGGACCATCGCAACCCGCTATG
TCTCGCTTGGAGATGTAGTGAATGTAGGGAATCCAACTCTTACACTGCTTGCTTCTGAGGGCAAAGAGGCCTTCATTGGT
ATTCCTGCTCACCAAATGCAAAAAGTCACCTCACTTTCTTCCCCAAACATCCGAGTTGGGCGCACAGAGTATGCCGTGGA
GCTATTGAATCCCGGCGCAATGGTCGACACTCAATCTCGTAGTGTCGGCTTGCGTTACCTGTTTCCTGAACAATCGTCGG
TATTAGAAGGGCAACTTGCCTACCTTAAATTCGATGAACAGATTGAAGAGCAAGGTTACTGGGTGCCATTAACCGGTTTG
ATTGATGGATTGCGCGGTGTGTGGAACATCTTTGTGATTGGTGAAGACAACAAGGTTGAACGTAGAAGTGTTCAGGTGTT
GTTTGCCAATAATCAACAAGCATACGTGAGTGGGGCGATTGAAGACGGTGAACAGGTCATTGCCAGTGGCTTACATCGCT
TAGTTCCGGGCCAAATCGTGAAACCAGTCAGCGCGGCTGAGTAG

Upstream 100 bases:

>100_bases
CTCGTTTTACGCTAAGCATTATGCTTTTTGTGATGGTTTTATCAATCATTAACGATGAAACTTATTTTTAACATAATCAA
ACTAGACAGTCTAGTTTGAT

Downstream 100 bases:

>100_bases
GTAATAGTATGAAAATTATAGAGACTATTTCCAACACGCGACTGCTTATCTTGATGACCGCGCTGCTGATGGTGAGCGGT
ATTTCTGCGTTCATGACCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Protein envC [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MVSLKKNIIEYRIGTVRMYKLMKGSAVAVALSAFLVGCGEKEQAQESVDSTAETASSVQTILTVETMALALSSSYAVQRE
YVGVVKAGQQANLGFELAGKVNEILVDVGDTVTTGQPLIRLDNQLLETESSQLKAQAEEVKAQLSLVAANLKRQRSLKAK
GFSAEAEIDSLTSEQRVLQANLLRIDASVKGNQLKLVKSTVRAPYSGTIATRYVSLGDVVNVGNPTLTLLASEGKEAFIG
IPAHQMQKVTSLSSPNIRVGRTEYAVELLNPGAMVDTQSRSVGLRYLFPEQSSVLEGQLAYLKFDEQIEEQGYWVPLTGL
IDGLRGVWNIFVIGEDNKVERRSVQVLFANNQQAYVSGAIEDGEQVIASGLHRLVPGQIVKPVSAAE

Sequences:

>Translated_387_residues
MVSLKKNIIEYRIGTVRMYKLMKGSAVAVALSAFLVGCGEKEQAQESVDSTAETASSVQTILTVETMALALSSSYAVQRE
YVGVVKAGQQANLGFELAGKVNEILVDVGDTVTTGQPLIRLDNQLLETESSQLKAQAEEVKAQLSLVAANLKRQRSLKAK
GFSAEAEIDSLTSEQRVLQANLLRIDASVKGNQLKLVKSTVRAPYSGTIATRYVSLGDVVNVGNPTLTLLASEGKEAFIG
IPAHQMQKVTSLSSPNIRVGRTEYAVELLNPGAMVDTQSRSVGLRYLFPEQSSVLEGQLAYLKFDEQIEEQGYWVPLTGL
IDGLRGVWNIFVIGEDNKVERRSVQVLFANNQQAYVSGAIEDGEQVIASGLHRLVPGQIVKPVSAAE
>Mature_387_residues
MVSLKKNIIEYRIGTVRMYKLMKGSAVAVALSAFLVGCGEKEQAQESVDSTAETASSVQTILTVETMALALSSSYAVQRE
YVGVVKAGQQANLGFELAGKVNEILVDVGDTVTTGQPLIRLDNQLLETESSQLKAQAEEVKAQLSLVAANLKRQRSLKAK
GFSAEAEIDSLTSEQRVLQANLLRIDASVKGNQLKLVKSTVRAPYSGTIATRYVSLGDVVNVGNPTLTLLASEGKEAFIG
IPAHQMQKVTSLSSPNIRVGRTEYAVELLNPGAMVDTQSRSVGLRYLFPEQSSVLEGQLAYLKFDEQIEEQGYWVPLTGL
IDGLRGVWNIFVIGEDNKVERRSVQVLFANNQQAYVSGAIEDGEQVIASGLHRLVPGQIVKPVSAAE

Specific function: May affect specific membrane functions, such as septum formation during cell division, and cell membrane permeability [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=368, Percent_Identity=22.554347826087, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081951, Length=189, Percent_Identity=26.984126984127, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41815; Mature: 41815

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKKNIIEYRIGTVRMYKLMKGSAVAVALSAFLVGCGEKEQAQESVDSTAETASSVQT
CCCHHHHHHHHHHCHHHEEHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ILTVETMALALSSSYAVQREYVGVVKAGQQANLGFELAGKVNEILVDVGDTVTTGQPLIR
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCHHH
LDNQLLETESSQLKAQAEEVKAQLSLVAANLKRQRSLKAKGFSAEAEIDSLTSEQRVLQA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
NLLRIDASVKGNQLKLVKSTVRAPYSGTIATRYVSLGDVVNVGNPTLTLLASEGKEAFIG
HHEEEECCCCCCEEEEEHHHHCCCCCCCHHEEEEECCCEEECCCCEEEEEECCCCEEEEE
IPAHQMQKVTSLSSPNIRVGRTEYAVELLNPGAMVDTQSRSVGLRYLFPEQSSVLEGQLA
CCHHHHHHHHCCCCCCEEECCHHEEEEEECCCCEEECCCCCCCEEEECCCCCCHHCCEEE
YLKFDEQIEEQGYWVPLTGLIDGLRGVWNIFVIGEDNKVERRSVQVLFANNQQAYVSGAI
EEEEHHHHHHCCCEEEHHHHHHHHHCEEEEEEEECCCCCCCEEEEEEEECCCEEEEECCH
EDGEQVIASGLHRLVPGQIVKPVSAAE
HCHHHHHHHHHHHHCCCHHCCCCCCCC
>Mature Secondary Structure
MVSLKKNIIEYRIGTVRMYKLMKGSAVAVALSAFLVGCGEKEQAQESVDSTAETASSVQT
CCCHHHHHHHHHHCHHHEEHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ILTVETMALALSSSYAVQREYVGVVKAGQQANLGFELAGKVNEILVDVGDTVTTGQPLIR
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCHHH
LDNQLLETESSQLKAQAEEVKAQLSLVAANLKRQRSLKAKGFSAEAEIDSLTSEQRVLQA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
NLLRIDASVKGNQLKLVKSTVRAPYSGTIATRYVSLGDVVNVGNPTLTLLASEGKEAFIG
HHEEEECCCCCCEEEEEHHHHCCCCCCCHHEEEEECCCEEECCCCEEEEEECCCCEEEEE
IPAHQMQKVTSLSSPNIRVGRTEYAVELLNPGAMVDTQSRSVGLRYLFPEQSSVLEGQLA
CCHHHHHHHHCCCCCCEEECCHHEEEEEECCCCEEECCCCCCCEEEECCCCCCHHCCEEE
YLKFDEQIEEQGYWVPLTGLIDGLRGVWNIFVIGEDNKVERRSVQVLFANNQQAYVSGAI
EEEEHHHHHHCCCEEEHHHHHHHHHCEEEEEEEECCCCCCCEEEEEEEECCCEEEEECCH
EDGEQVIASGLHRLVPGQIVKPVSAAE
HCHHHHHHHHHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1720861; 9278503 [H]