Click here to switch to the map view.

The map label for this gene is gsk [H]

Identifier: 218710010

GI number: 218710010

Start: 2176129

End: 2177433

Strand: Reverse

Name: gsk [H]

Synonym: VS_2030

Alternate gene names: 218710010

Gene position: 2177433-2176129 (Counterclockwise)

Preceding gene: 218710011

Following gene: 218710008

Centisome position: 66.0

GC content: 40.92

Gene sequence:

>1305_bases
ATGAAATTCCCTGGACAACGTAAATCAAAGCACTATTTTCCGGTTCACGCTCGTGACCCTTTAGTAAGCCAAGCTCAAAC
GAGCAAAAGAATGTCACGTACCCATATTATCGGTATTGACCAAACTTTGGTGGATATTGAAGCAAAGGTGAGTTCTGAGC
TAATCGAGAAATATGGCTTAAGTAAGGGACACTCTTTGGTTATTGGTGATGAAGCTGCTGAATCTTTGTATCAAGAATTA
AAAGAACAGTGCCTGATCACTAATGAATACGCAGGTGGCACGATCGGTAACACATTACACAATTACTCAGTATTGGCGGA
TGACCGTTCAACACTGTTAGGTGTAATGAGCCAAGATATTAAAATTGGTAGCTACGGTTACCGCTATTTATGTAATACAT
CAAGCAGAATGGATCTGAACCATTTACAAGGGGTAGATGGCGCAATTGGTCGCTGCTTTGCATTAATTACAGAAGATGGT
GAACGTACTTTCGCAATTAGCGAAGGACAAATGAACCAATTAAAACCAGAAAGCATCCCTGAGAAAATTTTCAAAAGTGC
TTCTGCTTTAGTATTAACGGCGTATTTAGTTCGTTGTAAACCAGGTGACCCTATGCCTGAAGCAACAATGAAAGCTATTG
AGTACGCGAAGAAATACGATGTACCTGTTGTTTTAACGCTTGGTACTAAATTCGTTATTCAAGATGATCCAGAGTTTTGG
AAAGATTTCCTTGAACAACATGTAACCGTTGTTGCAATGAACGAAGACGAGGCTGAAGCATTAACGGGTGAAAGCGATCC
TCTAGCTGCTTCAGACAAAGCACTAGATTGGGTAGACTTAGTTCTATGTACAGCAGGCCCTGTGGGCTTGTTTATGGCGG
GTTACACAGAAGATGCAGTGAAGCGTGAAACATCATTACCGTTGTTACCAGGCTCGATTGCTGAATTTAACCGTTATGAG
TTTAGTCGTCCCGCACATAAAGATTTATGTGAAAATCCAACGAAAATCTATTCGCATATCGCACCTTACATGGGCGGCCC
AGAAAAGATTAAGAATACTAATGGTGCCGGTGATGCTGCGTTGTCTGCTCTATTACATGATATGGCCGCTAATAAGTACC
ATAAAGAAAATGTGCCTAACTCAAGTAAGCATCAGCATTCATTCTTGACGTATTCTTCTTTCTCACAAGTTTGTAAATAT
TCAAACCGCGCAAGTTATGAAGTATTAGTTCAGCACTCGCCACGATTATCTCGAGGCCTTCCTGAAAGAGAAGATAGTCT
AGAAGAAGCGTACTGGGAAAGATAA

Upstream 100 bases:

>100_bases
AAATAGCCTAGCAAACGTTTGCTATGGTTTGAAAGATTGCCGCGTTAAATATAGCGCGGTAGAATCCGCCACCTATTTCC
CCTTGACTTAGACTAGCCCT

Downstream 100 bases:

>100_bases
GGCATTTTTTTGATTTATATTTCTAATAGTGAAATATAAAAAAGGCTCCGAAAGGAGCCTTTTTTGTTTCTGAATATATT
GAAGCCGTAAATAATACTTT

Product: inosine guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGQRKSKHYFPVHARDPLVSQAQTSKRMSRTHIIGIDQTLVDIEAKVSSELIEKYGLSKGHSLVIGDEAAESLYQEL
KEQCLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNHLQGVDGAIGRCFALITEDG
ERTFAISEGQMNQLKPESIPEKIFKSASALVLTAYLVRCKPGDPMPEATMKAIEYAKKYDVPVVLTLGTKFVIQDDPEFW
KDFLEQHVTVVAMNEDEAEALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDAVKRETSLPLLPGSIAEFNRYE
FSRPAHKDLCENPTKIYSHIAPYMGGPEKIKNTNGAGDAALSALLHDMAANKYHKENVPNSSKHQHSFLTYSSFSQVCKY
SNRASYEVLVQHSPRLSRGLPEREDSLEEAYWER

Sequences:

>Translated_434_residues
MKFPGQRKSKHYFPVHARDPLVSQAQTSKRMSRTHIIGIDQTLVDIEAKVSSELIEKYGLSKGHSLVIGDEAAESLYQEL
KEQCLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNHLQGVDGAIGRCFALITEDG
ERTFAISEGQMNQLKPESIPEKIFKSASALVLTAYLVRCKPGDPMPEATMKAIEYAKKYDVPVVLTLGTKFVIQDDPEFW
KDFLEQHVTVVAMNEDEAEALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDAVKRETSLPLLPGSIAEFNRYE
FSRPAHKDLCENPTKIYSHIAPYMGGPEKIKNTNGAGDAALSALLHDMAANKYHKENVPNSSKHQHSFLTYSSFSQVCKY
SNRASYEVLVQHSPRLSRGLPEREDSLEEAYWER
>Mature_434_residues
MKFPGQRKSKHYFPVHARDPLVSQAQTSKRMSRTHIIGIDQTLVDIEAKVSSELIEKYGLSKGHSLVIGDEAAESLYQEL
KEQCLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDIKIGSYGYRYLCNTSSRMDLNHLQGVDGAIGRCFALITEDG
ERTFAISEGQMNQLKPESIPEKIFKSASALVLTAYLVRCKPGDPMPEATMKAIEYAKKYDVPVVLTLGTKFVIQDDPEFW
KDFLEQHVTVVAMNEDEAEALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDAVKRETSLPLLPGSIAEFNRYE
FSRPAHKDLCENPTKIYSHIAPYMGGPEKIKNTNGAGDAALSALLHDMAANKYHKENVPNSSKHQHSFLTYSSFSQVCKY
SNRASYEVLVQHSPRLSRGLPEREDSLEEAYWER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=435, Percent_Identity=75.4022988505747, Blast_Score=706, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48276; Mature: 48276

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGQRKSKHYFPVHARDPLVSQAQTSKRMSRTHIIGIDQTLVDIEAKVSSELIEKYGL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHCC
SKGHSLVIGDEAAESLYQELKEQCLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDI
CCCCEEEECCHHHHHHHHHHHHHHEEECCCCCCCHHCHHHCCEEEECCHHHHHHHHHCCE
KIGSYGYRYLCNTSSRMDLNHLQGVDGAIGRCFALITEDGERTFAISEGQMNQLKPESIP
EECCCCEEEEECCCCCCCHHHHCCCCHHHHHEEEEEECCCCEEEEECCCCCCCCCCHHHH
EKIFKSASALVLTAYLVRCKPGDPMPEATMKAIEYAKKYDVPVVLTLGTKFVIQDDPEFW
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHH
KDFLEQHVTVVAMNEDEAEALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDAV
HHHHHCCEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHEECCCHHHH
KRETSLPLLPGSIAEFNRYEFSRPAHKDLCENPTKIYSHIAPYMGGPEKIKNTNGAGDAA
HHHCCCCCCCCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCHHHH
LSALLHDMAANKYHKENVPNSSKHQHSFLTYSSFSQVCKYSNRASYEVLVQHSPRLSRGL
HHHHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHCCCCCCEEEEEECCCHHHCCC
PEREDSLEEAYWER
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGQRKSKHYFPVHARDPLVSQAQTSKRMSRTHIIGIDQTLVDIEAKVSSELIEKYGL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHCC
SKGHSLVIGDEAAESLYQELKEQCLITNEYAGGTIGNTLHNYSVLADDRSTLLGVMSQDI
CCCCEEEECCHHHHHHHHHHHHHHEEECCCCCCCHHCHHHCCEEEECCHHHHHHHHHCCE
KIGSYGYRYLCNTSSRMDLNHLQGVDGAIGRCFALITEDGERTFAISEGQMNQLKPESIP
EECCCCEEEEECCCCCCCHHHHCCCCHHHHHEEEEEECCCCEEEEECCCCCCCCCCHHHH
EKIFKSASALVLTAYLVRCKPGDPMPEATMKAIEYAKKYDVPVVLTLGTKFVIQDDPEFW
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHH
KDFLEQHVTVVAMNEDEAEALTGESDPLAASDKALDWVDLVLCTAGPVGLFMAGYTEDAV
HHHHHCCEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHEECCCHHHH
KRETSLPLLPGSIAEFNRYEFSRPAHKDLCENPTKIYSHIAPYMGGPEKIKNTNGAGDAA
HHHCCCCCCCCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCCHHHHCCCCCCHHHH
LSALLHDMAANKYHKENVPNSSKHQHSFLTYSSFSQVCKYSNRASYEVLVQHSPRLSRGL
HHHHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHHCCCCCCEEEEEECCCHHHCCC
PEREDSLEEAYWER
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]