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The map label for this gene is mdtA [H]

Identifier: 218709968

GI number: 218709968

Start: 2135152

End: 2136267

Strand: Reverse

Name: mdtA [H]

Synonym: VS_1987

Alternate gene names: 218709968

Gene position: 2136267-2135152 (Counterclockwise)

Preceding gene: 218709969

Following gene: 218709967

Centisome position: 64.75

GC content: 43.1

Gene sequence:

>1116_bases
GTGAGTGGATCAAGGAAAGGGGGCTCTAACATGAAGACAGTATCAAAAGCCATCGGCCTATCATGTTTGGCGTTGTTGAC
AGCCTGTAAAGACAAAGGTGTCACTGAAGTCGAAAAGCTTCCTCTTGTTAAAGCCATTGAAATCTCCGTCTTAGACTTTA
ACGATAAACTCTATTTTCCAGCAGTGGCTAATGCTGCTGAGAAAGCGCACCTAAGTTTCCGTGTCGCTGGTGAGATTTTT
AAACTTGATGTCAAAGAAGGTGAACAAGTTAAAAAGGGTGATGTTCTTGCCGAGTTAGATCCAACAGATTATCAGTTGGA
CGTTGATAACGCTCAAGCTCGATACACAGTGATTAACAGCCAATACAGACGTTCAAGTCCGTTGGTCAAAAAGGGGTTAT
TGGCTAAGTCTCAATTCGATGAGATTGCCGCTCAGCGTCAAATCGCTTATGCCGAGTTAGAATTGGCAAAACTGCGTTTG
TCATTTACCAAGCTTCGCGCACCGGTTGATGGAATTATCTCTCGTGTCAGTGTTGACCAATACGAAAATATTCAGGTTGG
CCAACAGATTGTGAATATTCACAGTGTTGAGGATGTTGAAGTTGTTATCCAATTGCCTGACCAAATCTATGTAAATCAAC
CAAATGAAGCGACTATCTCGAATATTGAGGCAGTAGTTAGAGTTCCAAGTGGGAATGAATACAGTGCGGGGATAAAAGAG
TTTACGACTGAACCCGATCCAAACACAGGTACATTTACCGTCACGCTTGCTTTACCTATGCCAGAAGATGATTTGATTCT
TGACGGTATGGCCGTTGAGGTCACGTCAAATGGGCGTGATATCGGGTTGAAATTAAAAGCCGGCGTACTTATTCCTATTG
AGGCTGTGTTCAATGCCGATGGGGATGAGTTAACTCGTCAAAACTCTTACGTGTGGATTCTTAATGACGACAATACAGTA
TCTAAACAGCAAGTCGTATTAGGCAAAGCGAATCAGAAAACATTGCAGATAATCAAAGGATTAGAAATGGGGCAGCATGT
CGTTGTTGCAGGCGTATCGCGATTGCGAGATGGGATGACAGTGGAAGTATTGTCTCAGGAGACGAACAATGAGTGA

Upstream 100 bases:

>100_bases
ATAGTCATTGATGAAAAACGTCATATTATTTCGGGTCTTAACGACGGAGATCGCGTTGTGACCTCGGGCGTTAATGGATT
AGAAACTGGCGTCAAAGTTC

Downstream 100 bases:

>100_bases
AGTCAATAACAAGCCCCAAAGTGACGATCAACAGGGTGATGACCAAATCACTGGAGTGGCGGCTTATTTTATACGAAATA
AGGTCATTAGCTGGATGCTA

Product: membrane-fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSGSRKGGSNMKTVSKAIGLSCLALLTACKDKGVTEVEKLPLVKAIEISVLDFNDKLYFPAVANAAEKAHLSFRVAGEIF
KLDVKEGEQVKKGDVLAELDPTDYQLDVDNAQARYTVINSQYRRSSPLVKKGLLAKSQFDEIAAQRQIAYAELELAKLRL
SFTKLRAPVDGIISRVSVDQYENIQVGQQIVNIHSVEDVEVVIQLPDQIYVNQPNEATISNIEAVVRVPSGNEYSAGIKE
FTTEPDPNTGTFTVTLALPMPEDDLILDGMAVEVTSNGRDIGLKLKAGVLIPIEAVFNADGDELTRQNSYVWILNDDNTV
SKQQVVLGKANQKTLQIIKGLEMGQHVVVAGVSRLRDGMTVEVLSQETNNE

Sequences:

>Translated_371_residues
MSGSRKGGSNMKTVSKAIGLSCLALLTACKDKGVTEVEKLPLVKAIEISVLDFNDKLYFPAVANAAEKAHLSFRVAGEIF
KLDVKEGEQVKKGDVLAELDPTDYQLDVDNAQARYTVINSQYRRSSPLVKKGLLAKSQFDEIAAQRQIAYAELELAKLRL
SFTKLRAPVDGIISRVSVDQYENIQVGQQIVNIHSVEDVEVVIQLPDQIYVNQPNEATISNIEAVVRVPSGNEYSAGIKE
FTTEPDPNTGTFTVTLALPMPEDDLILDGMAVEVTSNGRDIGLKLKAGVLIPIEAVFNADGDELTRQNSYVWILNDDNTV
SKQQVVLGKANQKTLQIIKGLEMGQHVVVAGVSRLRDGMTVEVLSQETNNE
>Mature_370_residues
SGSRKGGSNMKTVSKAIGLSCLALLTACKDKGVTEVEKLPLVKAIEISVLDFNDKLYFPAVANAAEKAHLSFRVAGEIFK
LDVKEGEQVKKGDVLAELDPTDYQLDVDNAQARYTVINSQYRRSSPLVKKGLLAKSQFDEIAAQRQIAYAELELAKLRLS
FTKLRAPVDGIISRVSVDQYENIQVGQQIVNIHSVEDVEVVIQLPDQIYVNQPNEATISNIEAVVRVPSGNEYSAGIKEF
TTEPDPNTGTFTVTLALPMPEDDLILDGMAVEVTSNGRDIGLKLKAGVLIPIEAVFNADGDELTRQNSYVWILNDDNTVS
KQQVVLGKANQKTLQIIKGLEMGQHVVVAGVSRLRDGMTVEVLSQETNNE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=323, Percent_Identity=27.8637770897833, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789929, Length=379, Percent_Identity=26.3852242744063, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789665, Length=382, Percent_Identity=27.2251308900524, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786668, Length=379, Percent_Identity=24.0105540897098, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40557; Mature: 40426

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSRKGGSNMKTVSKAIGLSCLALLTACKDKGVTEVEKLPLVKAIEISVLDFNDKLYFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEEECCCCEECC
AVANAAEKAHLSFRVAGEIFKLDVKEGEQVKKGDVLAELDPTDYQLDVDNAQARYTVINS
HHHCCHHHHEEEEEEECEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEECC
QYRRSSPLVKKGLLAKSQFDEIAAQRQIAYAELELAKLRLSFTKLRAPVDGIISRVSVDQ
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
YENIQVGQQIVNIHSVEDVEVVIQLPDQIYVNQPNEATISNIEAVVRVPSGNEYSAGIKE
CCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCHHCCEEEEEECCCCCCCCCCHHH
FTTEPDPNTGTFTVTLALPMPEDDLILDGMAVEVTSNGRDIGLKLKAGVLIPIEAVFNAD
HCCCCCCCCCEEEEEEEECCCCCCEEECCEEEEEECCCCEEEEEEECCEEEEEHHEECCC
GDELTRQNSYVWILNDDNTVSKQQVVLGKANQKTLQIIKGLEMGQHVVVAGVSRLRDGMT
CHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEHHHHCCCCE
VEVLSQETNNE
EEEECCCCCCC
>Mature Secondary Structure 
SGSRKGGSNMKTVSKAIGLSCLALLTACKDKGVTEVEKLPLVKAIEISVLDFNDKLYFP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEEEEEEEECCCCEECC
AVANAAEKAHLSFRVAGEIFKLDVKEGEQVKKGDVLAELDPTDYQLDVDNAQARYTVINS
HHHCCHHHHEEEEEEECEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEECC
QYRRSSPLVKKGLLAKSQFDEIAAQRQIAYAELELAKLRLSFTKLRAPVDGIISRVSVDQ
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
YENIQVGQQIVNIHSVEDVEVVIQLPDQIYVNQPNEATISNIEAVVRVPSGNEYSAGIKE
CCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCHHCCEEEEEECCCCCCCCCCHHH
FTTEPDPNTGTFTVTLALPMPEDDLILDGMAVEVTSNGRDIGLKLKAGVLIPIEAVFNAD
HCCCCCCCCCEEEEEEEECCCCCCEEECCEEEEEECCCCEEEEEEECCEEEEEHHEECCC
GDELTRQNSYVWILNDDNTVSKQQVVLGKANQKTLQIIKGLEMGQHVVVAGVSRLRDGMT
CHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEEHHHHCCCCE
VEVLSQETNNE
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA