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The map label for this gene is pgsA [H]

Identifier: 218709935

GI number: 218709935

Start: 2097384

End: 2097941

Strand: Reverse

Name: pgsA [H]

Synonym: VS_1953

Alternate gene names: 218709935

Gene position: 2097941-2097384 (Counterclockwise)

Preceding gene: 218709936

Following gene: 218709934

Centisome position: 63.59

GC content: 44.8

Gene sequence:

>558_bases
ATGCGTTTGAATATACCTAACATTTTGTCCTTACTGAGACTATTTTTAATCCCAGTATTCGTTGTTGTTTTTTACCTACC
TTATGAATGGGCTCCTTTTGCTGCTGCAATGGTGTTTTGGGTAGCGGGTTTTACTGACTGGCTAGATGGCATGCTGGCTC
GTAAACTAGGACAAACGTCTCGCTTTGGTGCCTTTATTGACCCCGTGGCGGATAAAGTGCTTGTTGCTACTGCTCTTATC
TTAGTTACCGAGCATTATCACTCGATCTGGGTGACTATTCCTGCTGTGACCATGATTGGTCGTGAAATTATCATCTCGGC
GCTTCGTGAATGGATGGCTGAAATCGGCAAACGTGCAAGCGTTGCGGTATCTTGGGTTGGTAAAGTGAAAACCGTTTCTC
AGATGTTCGCTCTTTGGGTACTTATCTGGCGATACGACGACTGGATGGTTTGGGTGGGTTACATTGCACTCTATGTTGCA
ACCGTTCTTACTTACTGGTCAATGGCGCAATACTTGATGGCCGCCAAAGATGATTTGTTAGACGAAAAACACCATTGA

Upstream 100 bases:

>100_bases
CCGGGCATTAGTCATTCTTTGGCAGAAAACATTTATCAAGCATTGAAACAATAGTAAAAATCCCGCACCATTAAAGCGCA
ATTGATAAGAGCCTAATAAT

Downstream 100 bases:

>100_bases
TGAAGAAGCGAGCTGAGGCTCGCTTTTTTGATCTTTAACCTAAGGTTAAATTATCAATAGTGGATATCTAATGTGATATA
GATCTCCTTTGAATAGCCTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRLNIPNILSLLRLFLIPVFVVVFYLPYEWAPFAAAMVFWVAGFTDWLDGMLARKLGQTSRFGAFIDPVADKVLVATALI
LVTEHYHSIWVTIPAVTMIGREIIISALREWMAEIGKRASVAVSWVGKVKTVSQMFALWVLIWRYDDWMVWVGYIALYVA
TVLTYWSMAQYLMAAKDDLLDEKHH

Sequences:

>Translated_185_residues
MRLNIPNILSLLRLFLIPVFVVVFYLPYEWAPFAAAMVFWVAGFTDWLDGMLARKLGQTSRFGAFIDPVADKVLVATALI
LVTEHYHSIWVTIPAVTMIGREIIISALREWMAEIGKRASVAVSWVGKVKTVSQMFALWVLIWRYDDWMVWVGYIALYVA
TVLTYWSMAQYLMAAKDDLLDEKHH
>Mature_185_residues
MRLNIPNILSLLRLFLIPVFVVVFYLPYEWAPFAAAMVFWVAGFTDWLDGMLARKLGQTSRFGAFIDPVADKVLVATALI
LVTEHYHSIWVTIPAVTMIGREIIISALREWMAEIGKRASVAVSWVGKVKTVSQMFALWVLIWRYDDWMVWVGYIALYVA
TVLTYWSMAQYLMAAKDDLLDEKHH

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=182, Percent_Identity=66.4835164835165, Blast_Score=247, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21276; Mature: 21276

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNIPNILSLLRLFLIPVFVVVFYLPYEWAPFAAAMVFWVAGFTDWLDGMLARKLGQTS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RFGAFIDPVADKVLVATALILVTEHYHSIWVTIPAVTMIGREIIISALREWMAEIGKRAS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAVSWVGKVKTVSQMFALWVLIWRYDDWMVWVGYIALYVATVLTYWSMAQYLMAAKDDLL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEKHH
CCCCC
>Mature Secondary Structure
MRLNIPNILSLLRLFLIPVFVVVFYLPYEWAPFAAAMVFWVAGFTDWLDGMLARKLGQTS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RFGAFIDPVADKVLVATALILVTEHYHSIWVTIPAVTMIGREIIISALREWMAEIGKRAS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VAVSWVGKVKTVSQMFALWVLIWRYDDWMVWVGYIALYVATVLTYWSMAQYLMAAKDDLL
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEKHH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]