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The map label for this gene is hlyB [H]

Identifier: 218709894

GI number: 218709894

Start: 2047530

End: 2049413

Strand: Reverse

Name: hlyB [H]

Synonym: VS_1907

Alternate gene names: 218709894

Gene position: 2049413-2047530 (Counterclockwise)

Preceding gene: 218709895

Following gene: 218709887

Centisome position: 62.12

GC content: 45.49

Gene sequence:

>1884_bases
ATGAAATTAACACTTAAGCAGAAGTTGATAGGTGCTAGCCTATCTGCTGTTATCGTCATGGCAACAGCCTTGACTTGGTT
ATCAGCAAACCAATTATTTGAAGAGACTCGTAATGGCGTATACCAACGAGCTGAAAGCGTATCTGAAGCAGCATCTGAAG
GTATTAAAAACTGGATTGATATTCGCACGGATATCGCATCAGCGTTTAATGACTTTTCACGAGAGGATGATGTTGTTCCT
TTCCTTAAGCAAGCTCGTGTAGCGGGTGGCTTTGACGATATCTTTTTAGGTACTCCAGAAGGCGGAATGTACCGTTCACA
TCCTGAACGTAATCGTGCAGATTACGACCCTCGTCAACGCCCTTGGTACCAGGAAGCAAACGCAGCCGGTAAGCAAATTA
TTACAACCGCTTATCAAGATGCGATTACCCAAGCGCTTCTAGTTACGATTGCTGAACCTGTTCGTCATAACGGTAAGCTT
GTTGGTGTTGTTGGTGCGGATGTACTTATTGATCAACTAGTCAACGATGTTATCAGCTTAGATGTTGGTGACAACGCTTA
CGCAATGCTCATTGATGCCTCTGACGGCACATTCCTAGCACACCCAGACTCAGCACTGAGCCTTAAGCCTGTAAGCCAGC
TTTCAAACGACATTTCTATGCCTATCATCGAAAACGCAGTGCGTACGGGTAGCATCGAGATCATCAAAGAGCGCGGTGCT
GAGAAGCTTCTTTACTTCACTAATGTGCCTAATACGAACTGGATTTTCGCAGTTCAGATGGACAAAGCAACAGAAGAAGC
GAATCACTCAATACTTCTTACGCAACTCATTACTACAGCGGTTGTAATTACTCTGATCGTTATCGTGTTGGTTTCTATGT
TGGTTAGTTTCCTATTCCGCGACTTAAACCGCGTTTCAGCGGCACTTGAAGAAATTGCTTCAGGCGAGGGCGACTTGACT
CAACGTCTTGAGCTTAAAAGTGATGACGAAATTGGTAAACTTGCGGCAAATTTCAATCATTTTGTGGGCAACATGCACAC
CATGGTACTCAAGCTAAGTGAAGTGTCTGCTGCATTGGGTAACCAAGCACGTCAAACAGCTTCTCAAGCTGAAGAGCGTA
GTGCTCGCATTCAGATGCAACAAGACGAAATCAATATGGTAGCAACAGCCGTGAACGAAATGGCTGCAGCAACACAAGAG
ATTGCGGGTAACGCTGATCAAACTGCACAGAATTCATCTGAGGCCGTTGGCGCGTGTGAGCACGGTACGGGTCAAGTTAC
ACAGACTCAAAGCTCAATCCAAAACCTTGCACAAGAAGTTCAAGTTGCAACGAACGTGATTCTTGAGCTAGAAGAGCACG
GCAATAGCATCAACGCTATCTTGTCTAACATTCAAGGCATTGCTGAACAAACTAACTTACTTGCACTTAACGCGGCGATT
GAAGCTGCCCGTGCTGGCGAACAAGGTCGCGGTTTTGCGGTTGTTGCTGATGAAGTGAGAGTTTTGAGCCAACGTACACA
CGGTTCAACTCAAGAAATTCAACAAACGATTGAATTACTGCAAGGTACAACGGGCAAAGCGGTAAGTATCATGAACGATA
GCCGAACGCTTGCTGAAACCAGTGTTGATGACTCAAACTCAGCGGCCGCTAGCTTAACGCAAATTCATGCTGCTGTTGAA
CGTATCAGTGATATGGCGACTCAAATCGCTTCTGCTGCAGAAGAGCAAGCGTCAGTAACGTCTGAGATTACTCGTAACAC
TGAAGGAATCCGTGACGTATCTAACGAGCTAGCAGGTGAAGCGCACCAAGCTGCAGAACAAGCTGCTCAGCTTTCTGAAC
TGTCTAATGAACTAGAAAATGAAATCAGCCGTTTTAAGCTGTAA

Upstream 100 bases:

>100_bases
ATTGCAAATATAATGTGATGTGAAACTGTGAAATAGCTCGAATCGTTTACTTAAATTGGGTAGTATTCGCTAGATTTTCC
ACCACTCGTGAAACTTACTA

Downstream 100 bases:

>100_bases
TTATAGATAGATAGATAGAAGCCCCAACTTAGGTTAGGGCTTTTTTATGTTCGCTTTTTAGAAGAAGCAAAATGTCGTGA
TCTAATCATGCTGGGCTATT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MKLTLKQKLIGASLSAVIVMATALTWLSANQLFEETRNGVYQRAESVSEAASEGIKNWIDIRTDIASAFNDFSREDDVVP
FLKQARVAGGFDDIFLGTPEGGMYRSHPERNRADYDPRQRPWYQEANAAGKQIITTAYQDAITQALLVTIAEPVRHNGKL
VGVVGADVLIDQLVNDVISLDVGDNAYAMLIDASDGTFLAHPDSALSLKPVSQLSNDISMPIIENAVRTGSIEIIKERGA
EKLLYFTNVPNTNWIFAVQMDKATEEANHSILLTQLITTAVVITLIVIVLVSMLVSFLFRDLNRVSAALEEIASGEGDLT
QRLELKSDDEIGKLAANFNHFVGNMHTMVLKLSEVSAALGNQARQTASQAEERSARIQMQQDEINMVATAVNEMAAATQE
IAGNADQTAQNSSEAVGACEHGTGQVTQTQSSIQNLAQEVQVATNVILELEEHGNSINAILSNIQGIAEQTNLLALNAAI
EAARAGEQGRGFAVVADEVRVLSQRTHGSTQEIQQTIELLQGTTGKAVSIMNDSRTLAETSVDDSNSAAASLTQIHAAVE
RISDMATQIASAAEEQASVTSEITRNTEGIRDVSNELAGEAHQAAEQAAQLSELSNELENEISRFKL

Sequences:

>Translated_627_residues
MKLTLKQKLIGASLSAVIVMATALTWLSANQLFEETRNGVYQRAESVSEAASEGIKNWIDIRTDIASAFNDFSREDDVVP
FLKQARVAGGFDDIFLGTPEGGMYRSHPERNRADYDPRQRPWYQEANAAGKQIITTAYQDAITQALLVTIAEPVRHNGKL
VGVVGADVLIDQLVNDVISLDVGDNAYAMLIDASDGTFLAHPDSALSLKPVSQLSNDISMPIIENAVRTGSIEIIKERGA
EKLLYFTNVPNTNWIFAVQMDKATEEANHSILLTQLITTAVVITLIVIVLVSMLVSFLFRDLNRVSAALEEIASGEGDLT
QRLELKSDDEIGKLAANFNHFVGNMHTMVLKLSEVSAALGNQARQTASQAEERSARIQMQQDEINMVATAVNEMAAATQE
IAGNADQTAQNSSEAVGACEHGTGQVTQTQSSIQNLAQEVQVATNVILELEEHGNSINAILSNIQGIAEQTNLLALNAAI
EAARAGEQGRGFAVVADEVRVLSQRTHGSTQEIQQTIELLQGTTGKAVSIMNDSRTLAETSVDDSNSAAASLTQIHAAVE
RISDMATQIASAAEEQASVTSEITRNTEGIRDVSNELAGEAHQAAEQAAQLSELSNELENEISRFKL
>Mature_627_residues
MKLTLKQKLIGASLSAVIVMATALTWLSANQLFEETRNGVYQRAESVSEAASEGIKNWIDIRTDIASAFNDFSREDDVVP
FLKQARVAGGFDDIFLGTPEGGMYRSHPERNRADYDPRQRPWYQEANAAGKQIITTAYQDAITQALLVTIAEPVRHNGKL
VGVVGADVLIDQLVNDVISLDVGDNAYAMLIDASDGTFLAHPDSALSLKPVSQLSNDISMPIIENAVRTGSIEIIKERGA
EKLLYFTNVPNTNWIFAVQMDKATEEANHSILLTQLITTAVVITLIVIVLVSMLVSFLFRDLNRVSAALEEIASGEGDLT
QRLELKSDDEIGKLAANFNHFVGNMHTMVLKLSEVSAALGNQARQTASQAEERSARIQMQQDEINMVATAVNEMAAATQE
IAGNADQTAQNSSEAVGACEHGTGQVTQTQSSIQNLAQEVQVATNVILELEEHGNSINAILSNIQGIAEQTNLLALNAAI
EAARAGEQGRGFAVVADEVRVLSQRTHGSTQEIQQTIELLQGTTGKAVSIMNDSRTLAETSVDDSNSAAASLTQIHAAVE
RISDMATQIASAAEEQASVTSEITRNTEGIRDVSNELAGEAHQAAEQAAQLSELSNELENEISRFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=311, Percent_Identity=31.1897106109325, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788195, Length=281, Percent_Identity=33.8078291814947, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787690, Length=349, Percent_Identity=27.7936962750716, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788194, Length=254, Percent_Identity=32.6771653543307, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=366, Percent_Identity=28.1420765027322, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67597; Mature: 67597

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTLKQKLIGASLSAVIVMATALTWLSANQLFEETRNGVYQRAESVSEAASEGIKNWID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRTDIASAFNDFSREDDVVPFLKQARVAGGFDDIFLGTPEGGMYRSHPERNRADYDPRQR
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
PWYQEANAAGKQIITTAYQDAITQALLVTIAEPVRHNGKLVGVVGADVLIDQLVNDVISL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHEE
DVGDNAYAMLIDASDGTFLAHPDSALSLKPVSQLSNDISMPIIENAVRTGSIEIIKERGA
CCCCCEEEEEEECCCCEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCC
EKLLYFTNVPNTNWIFAVQMDKATEEANHSILLTQLITTAVVITLIVIVLVSMLVSFLFR
CEEEEEECCCCCCEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLNRVSAALEEIASGEGDLTQRLELKSDDEIGKLAANFNHFVGNMHTMVLKLSEVSAALG
HHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQARQTASQAEERSARIQMQQDEINMVATAVNEMAAATQEIAGNADQTAQNSSEAVGACE
HHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHCCCCC
HGTGQVTQTQSSIQNLAQEVQVATNVILELEEHGNSINAILSNIQGIAEQTNLLALNAAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEHHHHH
EAARAGEQGRGFAVVADEVRVLSQRTHGSTQEIQQTIELLQGTTGKAVSIMNDSRTLAET
HHHHCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHC
SVDDSNSAAASLTQIHAAVERISDMATQIASAAEEQASVTSEITRNTEGIRDVSNELAGE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCH
AHQAAEQAAQLSELSNELENEISRFKL
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLTLKQKLIGASLSAVIVMATALTWLSANQLFEETRNGVYQRAESVSEAASEGIKNWID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRTDIASAFNDFSREDDVVPFLKQARVAGGFDDIFLGTPEGGMYRSHPERNRADYDPRQR
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
PWYQEANAAGKQIITTAYQDAITQALLVTIAEPVRHNGKLVGVVGADVLIDQLVNDVISL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHEE
DVGDNAYAMLIDASDGTFLAHPDSALSLKPVSQLSNDISMPIIENAVRTGSIEIIKERGA
CCCCCEEEEEEECCCCEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCC
EKLLYFTNVPNTNWIFAVQMDKATEEANHSILLTQLITTAVVITLIVIVLVSMLVSFLFR
CEEEEEECCCCCCEEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLNRVSAALEEIASGEGDLTQRLELKSDDEIGKLAANFNHFVGNMHTMVLKLSEVSAALG
HHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQARQTASQAEERSARIQMQQDEINMVATAVNEMAAATQEIAGNADQTAQNSSEAVGACE
HHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHCCCCC
HGTGQVTQTQSSIQNLAQEVQVATNVILELEEHGNSINAILSNIQGIAEQTNLLALNAAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEHHHHH
EAARAGEQGRGFAVVADEVRVLSQRTHGSTQEIQQTIELLQGTTGKAVSIMNDSRTLAET
HHHHCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHC
SVDDSNSAAASLTQIHAAVERISDMATQIASAAEEQASVTSEITRNTEGIRDVSNELAGE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCH
AHQAAEQAAQLSELSNELENEISRFKL
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]