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The map label for this gene is ydcR [H]

Identifier: 218709802

GI number: 218709802

Start: 1947164

End: 1948567

Strand: Reverse

Name: ydcR [H]

Synonym: VS_1814

Alternate gene names: 218709802

Gene position: 1948567-1947164 (Counterclockwise)

Preceding gene: 218709805

Following gene: 218709801

Centisome position: 59.06

GC content: 45.44

Gene sequence:

>1404_bases
ATGGCGCGTTATGAAGAGCTTGCAAAGGATATTCGAACTCAGATAGCGAACAACACGTGGCGTTCAGGAGAAAAGATCCC
TTCCGTCCGCATGAGTTGTCGCAATTACAGCGTCAGCAATAGTACTGTCTTACAAGCCTACCAATTGTTAGAAAGTGAAG
GGTGGATCATCGCTAAGCCTCAGTCGGGCTACTTTGTTGCACCACGTGTGGACGGCGTTGATTATGAACTGCCGTTAGTA
CACAAAAAGAAAGCCATTAATGATCGCTTATTCGACTTTTTGAAATCGAGTTCGGCAGAGGGGGTTATTCCTTTTGGATC
AGCATTCCCAGATCCTGACCTTTTTCCTTTGCCTACCTTGACTCGAAACCTCGCCAGTGCGGGAAGGAAGATGACAGGTG
CTAGTGTGATCAATAATCTGCCACCGGGCAGTGAGTCCCTAAGAAGACAAATCGCTCAACGTTACCTGCAGCAAGGTATT
ACCGTTAACCATCAAGATATCGTGATTACTTCTGGTGCGATGGAAGCGCTTAACTTGAGCCTTCAAACTGTAACCAAGCC
CGGTGACTACGTTGTGATTGAATCTCCCGCTTTCTATGGTGCTCTGCAAGCTGTCGAGAGGTTAGGACTCAACCCTATCG
AAGTGGATGTTTGTCCAATCAATGGATTGAATATTGAGCAGTTTGAAAGCGCACTACAAAATCAGGATGTGAAAGCGTGT
TGGCTGATGACGACGTTTCAAAACCCGACAGGGACAAGTTTGTCTGAAGATGCGAAGCGCCGAGTGGTTGAGGTTGCTGA
ACAATACAAGACTTATATTATCGAAGATGATGTTTACGGCGACCTATATTTCGAAGGGCATAAACCTAAACCGCTAAAAG
CATTTGATAAAACAGACTTAGTGTTGCTATGCGGCTCTTACTCTAAGAGTTTATGCCCTGGCTATCGTGTTGGTTGGGTG
GTGAGTTCGCGTTTTAACGATGCGATTCAAAAACTTCAGCTTCTTTCTACACTGTCGAGTAGTGCTCCTGTGCAGCTTGG
TGTTGCGCACTTCTTGACACACGAAAGCTACGACAATCACCTTCGTAAATTGCGTAAAAATCTTCTAATGAGAAAAAAGC
GATTTATAGAGGTCATTAAGCAATATTTCCCACATTCCATCGAGATAGAAGATCCAGCTGGCGGCTACTTTGTATGGATT
CGTTTTTCTGCCAAATTCGACAGTCAACAATTCCATCAGTTAGCGATTGCTCAAGGCATTAGCGTCGCCTCTGGAGACCT
CTTTAGCGAGTTGGGCAGAGTAGACAACGCGATTAGATTGAACTTCTCTTATGAACTCACCGCAGAGAAAGAGCAAGCGC
TGCTCTTACTTGGTAAGCTTGCGCGTCAACTTACGCACTCGTAA

Upstream 100 bases:

>100_bases
TTATAGAAATTAGGCTCAATCATATGGATAGCAGCAATAGTTGTTAACGTTAGTGATAAAATCTCAGGCTTATTAGAATT
TCTCTAGGTAGTACAATTAG

Downstream 100 bases:

>100_bases
AACCGTAAGTCACTCATAAAAAAGACAATGATTCCAACTGTACGGACTGATTCCGATGCAACTGTACGCCTTCTTGACCA
ACGAGTTGTGATTCAATATC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYSVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPRVDGVDYELPLV
HKKKAINDRLFDFLKSSSAEGVIPFGSAFPDPDLFPLPTLTRNLASAGRKMTGASVINNLPPGSESLRRQIAQRYLQQGI
TVNHQDIVITSGAMEALNLSLQTVTKPGDYVVIESPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFESALQNQDVKAC
WLMTTFQNPTGTSLSEDAKRRVVEVAEQYKTYIIEDDVYGDLYFEGHKPKPLKAFDKTDLVLLCGSYSKSLCPGYRVGWV
VSSRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNHLRKLRKNLLMRKKRFIEVIKQYFPHSIEIEDPAGGYFVWI
RFSAKFDSQQFHQLAIAQGISVASGDLFSELGRVDNAIRLNFSYELTAEKEQALLLLGKLARQLTHS

Sequences:

>Translated_467_residues
MARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYSVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPRVDGVDYELPLV
HKKKAINDRLFDFLKSSSAEGVIPFGSAFPDPDLFPLPTLTRNLASAGRKMTGASVINNLPPGSESLRRQIAQRYLQQGI
TVNHQDIVITSGAMEALNLSLQTVTKPGDYVVIESPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFESALQNQDVKAC
WLMTTFQNPTGTSLSEDAKRRVVEVAEQYKTYIIEDDVYGDLYFEGHKPKPLKAFDKTDLVLLCGSYSKSLCPGYRVGWV
VSSRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNHLRKLRKNLLMRKKRFIEVIKQYFPHSIEIEDPAGGYFVWI
RFSAKFDSQQFHQLAIAQGISVASGDLFSELGRVDNAIRLNFSYELTAEKEQALLLLGKLARQLTHS
>Mature_466_residues
ARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYSVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPRVDGVDYELPLVH
KKKAINDRLFDFLKSSSAEGVIPFGSAFPDPDLFPLPTLTRNLASAGRKMTGASVINNLPPGSESLRRQIAQRYLQQGIT
VNHQDIVITSGAMEALNLSLQTVTKPGDYVVIESPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFESALQNQDVKACW
LMTTFQNPTGTSLSEDAKRRVVEVAEQYKTYIIEDDVYGDLYFEGHKPKPLKAFDKTDLVLLCGSYSKSLCPGYRVGWVV
SSRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNHLRKLRKNLLMRKKRFIEVIKQYFPHSIEIEDPAGGYFVWIR
FSAKFDSQQFHQLAIAQGISVASGDLFSELGRVDNAIRLNFSYELTAEKEQALLLLGKLARQLTHS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=402, Percent_Identity=23.8805970149254, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI33469970, Length=402, Percent_Identity=23.8805970149254, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507369, Length=239, Percent_Identity=25.9414225941423, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1787710, Length=466, Percent_Identity=45.4935622317597, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1790797, Length=467, Percent_Identity=33.1905781584582, Blast_Score=276, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17567663, Length=185, Percent_Identity=25.4054054054054, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=324, Percent_Identity=23.7654320987654, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321929, Length=221, Percent_Identity=23.9819004524887, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=256, Percent_Identity=24.609375, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356535, Length=378, Percent_Identity=23.2804232804233, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=359, Percent_Identity=23.6768802228412, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52337; Mature: 52206

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYSVSNSTVLQAYQLLESEGWIIAKP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECC
QSGYFVAPRVDGVDYELPLVHKKKAINDRLFDFLKSSSAEGVIPFGSAFPDPDLFPLPTL
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHH
TRNLASAGRKMTGASVINNLPPGSESLRRQIAQRYLQQGITVNHQDIVITSGAMEALNLS
HHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCCE
LQTVTKPGDYVVIESPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFESALQNQDVKAC
EEEECCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEE
WLMTTFQNPTGTSLSEDAKRRVVEVAEQYKTYIIEDDVYGDLYFEGHKPKPLKAFDKTDL
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCCCCCE
VLLCGSYSKSLCPGYRVGWVVSSRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNH
EEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHH
LRKLRKNLLMRKKRFIEVIKQYFPHSIEIEDPAGGYFVWIRFSAKFDSQQFHQLAIAQGI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHCC
SVASGDLFSELGRVDNAIRLNFSYELTAEKEQALLLLGKLARQLTHS
CCCCCHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYSVSNSTVLQAYQLLESEGWIIAKP
CHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECC
QSGYFVAPRVDGVDYELPLVHKKKAINDRLFDFLKSSSAEGVIPFGSAFPDPDLFPLPTL
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHH
TRNLASAGRKMTGASVINNLPPGSESLRRQIAQRYLQQGITVNHQDIVITSGAMEALNLS
HHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCCE
LQTVTKPGDYVVIESPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFESALQNQDVKAC
EEEECCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEE
WLMTTFQNPTGTSLSEDAKRRVVEVAEQYKTYIIEDDVYGDLYFEGHKPKPLKAFDKTDL
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCCCCCE
VLLCGSYSKSLCPGYRVGWVVSSRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNH
EEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHH
LRKLRKNLLMRKKRFIEVIKQYFPHSIEIEDPAGGYFVWIRFSAKFDSQQFHQLAIAQGI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHCC
SVASGDLFSELGRVDNAIRLNFSYELTAEKEQALLLLGKLARQLTHS
CCCCCHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]