Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 218709788

GI number: 218709788

Start: 1928522

End: 1930219

Strand: Reverse

Name: luxQ [H]

Synonym: VS_1800

Alternate gene names: 218709788

Gene position: 1930219-1928522 (Counterclockwise)

Preceding gene: 218709789

Following gene: 218709787

Centisome position: 58.5

GC content: 42.99

Gene sequence:

>1698_bases
ATGGATCTGGCATCTGCCCAAGAGAAAAAACTTAAACGTCAAATAGCAGCACGGAAAGTGGCTGAAGCTTTGTTGGAGCA
AAAGAGTCTCGAGCTGTTTGAGGCCAATCAACAGCTTGAACTTGCGTTGCGCCAATTAGAAAAGCGTTCAAATGCGAATA
TTCGACGGATCGAATTCCAAGAACAAATCGACAACCTGTTGATTGATTTCGGACGCGCGTTTCTGAGGAGTGATCTCGAT
GACGTGATGTTGTCCCAATTGACGGCGAGTGTAACTAACAGTTATCTAATTGAAGCCAGTCGCTTGGTTTTACCCCCCAA
TCTAATCCCTCAGTTACAAACCCATGACTATGGTGATGAAACAGTCGAGGTAATAGAGAAAGACATTCAAGAACCTCATT
GGCAAGGTTGCTTGCTTACCGTGCCATTAGAGGTCGAAAAAGTGATTGTGGGCGCGTTAATCGTTCAGGTCAGGTTGTTA
GATCAAGACTACGAATTCATCCAAAGCCAACTGTTGTTAGTGACGGACCTTATCTGCAGTGCGTTAACTCATCAACTTGC
GATTAACCGAAATATAGAATCACGTAAACGAGCGGAAGAGTCCGAGAGGGCAACCCGCGACTTTGTCGCCATGATTAACC
ATGAGCTAAGAACTCCGCTCAATGGTTTGCTAGGTAGTGCCGAATTGATCAGCGATACCGAACTCAGCAATTCTCAGCGT
GAAATAGTGAATAACCTGAGTCAATCTGGAGAGTTTCTTAGAACCATCATTAATGACCTTCTCGATTACAGTAAAATCAA
TGCGGGTATGCTGGAATTAATTCCCAAAACATTTGCACTCCAAGATTTGAAAAATACCATTGATAGTATTTTTACCAATC
GAGCGATTGAAAAGCAGATTCAGTTTGATGTCAATGTAACCGATGGGGTACCCAGTCACTTCTACGGTGACTTAGAGCGT
ATTACTCAATTGTTCGTGAACTTAATCGGCAATGCAATTAAATTCACCGATCAAGGCCATGTGAGCGTAGAGATAAAATG
GCTTAACGACCAATTTATTTTTTCTGTTGAGGATAGTGGCGTTGGTATTGCTCAATCTGCTATTAAGACACTGTTTGAAC
CTTTTACACAGGCCGATAACTCAAGTAGCCGAAATTACGAAGGGACAGGGCTTGGTTTAGCGATTTGTCGCAAGCTAGCT
GCGTTAATGAGGGGAGACATTGAGGTGAGCAGTATTGTTGGTTCGGGTACGACATTTACCATTTCACTCCCTCTTCAAGT
TGTCGATACACTGGCTGAGCGCGATAGTGTCGCCAAAGGTTTTGAGTCTGAGGTTGAATTGACATTGCTTAAAGTGCTGG
TGGTTGATGATATTAAGATGAACCAGATCATCATCCAACAAATGCTACGCAAATACGAAATAGAGCCAGCGATTGCCGGT
AATGGTATAGAAGGGTTGGAATTAGCGTCGAATAATGAGTATGACATTGTGTTTATGGATTGCCGGATGCCAGTCATGGA
TGGTTTTGAAGCGACGAAGAAACTGCGAAGTTCAGGATATAGCCAACCAATTATTGCATTAACCGCTGGTACGACAAAAG
AAGAGCGAGAGTTGTGTATTGAATCTGGTATGGACGATATATTGAGTAAACCCTATACCGCTAACGACTTAGTGATAATG
CTGAATAAGTGGGGCTAA

Upstream 100 bases:

>100_bases
GGGTGTGCTGACTATCATGGTGAAACCATCGTGGTAGAAATGACACCTCAGAATGATGACCAAAGTGTGGTTAGGTTTAA
TCTCAAAGTAGAAAAGTGAT

Downstream 100 bases:

>100_bases
TAAATATCATTACCTTTGTAGTGAGTGAATATGTAACGTTATTGATTTGTCTCTAATGTCTTGAGTATATTGTCAATGTA
ACAAGTGAGCTGACAATGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MDLASAQEKKLKRQIAARKVAEALLEQKSLELFEANQQLELALRQLEKRSNANIRRIEFQEQIDNLLIDFGRAFLRSDLD
DVMLSQLTASVTNSYLIEASRLVLPPNLIPQLQTHDYGDETVEVIEKDIQEPHWQGCLLTVPLEVEKVIVGALIVQVRLL
DQDYEFIQSQLLLVTDLICSALTHQLAINRNIESRKRAEESERATRDFVAMINHELRTPLNGLLGSAELISDTELSNSQR
EIVNNLSQSGEFLRTIINDLLDYSKINAGMLELIPKTFALQDLKNTIDSIFTNRAIEKQIQFDVNVTDGVPSHFYGDLER
ITQLFVNLIGNAIKFTDQGHVSVEIKWLNDQFIFSVEDSGVGIAQSAIKTLFEPFTQADNSSSRNYEGTGLGLAICRKLA
ALMRGDIEVSSIVGSGTTFTISLPLQVVDTLAERDSVAKGFESEVELTLLKVLVVDDIKMNQIIIQQMLRKYEIEPAIAG
NGIEGLELASNNEYDIVFMDCRMPVMDGFEATKKLRSSGYSQPIIALTAGTTKEERELCIESGMDDILSKPYTANDLVIM
LNKWG

Sequences:

>Translated_565_residues
MDLASAQEKKLKRQIAARKVAEALLEQKSLELFEANQQLELALRQLEKRSNANIRRIEFQEQIDNLLIDFGRAFLRSDLD
DVMLSQLTASVTNSYLIEASRLVLPPNLIPQLQTHDYGDETVEVIEKDIQEPHWQGCLLTVPLEVEKVIVGALIVQVRLL
DQDYEFIQSQLLLVTDLICSALTHQLAINRNIESRKRAEESERATRDFVAMINHELRTPLNGLLGSAELISDTELSNSQR
EIVNNLSQSGEFLRTIINDLLDYSKINAGMLELIPKTFALQDLKNTIDSIFTNRAIEKQIQFDVNVTDGVPSHFYGDLER
ITQLFVNLIGNAIKFTDQGHVSVEIKWLNDQFIFSVEDSGVGIAQSAIKTLFEPFTQADNSSSRNYEGTGLGLAICRKLA
ALMRGDIEVSSIVGSGTTFTISLPLQVVDTLAERDSVAKGFESEVELTLLKVLVVDDIKMNQIIIQQMLRKYEIEPAIAG
NGIEGLELASNNEYDIVFMDCRMPVMDGFEATKKLRSSGYSQPIIALTAGTTKEERELCIESGMDDILSKPYTANDLVIM
LNKWG
>Mature_565_residues
MDLASAQEKKLKRQIAARKVAEALLEQKSLELFEANQQLELALRQLEKRSNANIRRIEFQEQIDNLLIDFGRAFLRSDLD
DVMLSQLTASVTNSYLIEASRLVLPPNLIPQLQTHDYGDETVEVIEKDIQEPHWQGCLLTVPLEVEKVIVGALIVQVRLL
DQDYEFIQSQLLLVTDLICSALTHQLAINRNIESRKRAEESERATRDFVAMINHELRTPLNGLLGSAELISDTELSNSQR
EIVNNLSQSGEFLRTIINDLLDYSKINAGMLELIPKTFALQDLKNTIDSIFTNRAIEKQIQFDVNVTDGVPSHFYGDLER
ITQLFVNLIGNAIKFTDQGHVSVEIKWLNDQFIFSVEDSGVGIAQSAIKTLFEPFTQADNSSSRNYEGTGLGLAICRKLA
ALMRGDIEVSSIVGSGTTFTISLPLQVVDTLAERDSVAKGFESEVELTLLKVLVVDDIKMNQIIIQQMLRKYEIEPAIAG
NGIEGLELASNNEYDIVFMDCRMPVMDGFEATKKLRSSGYSQPIIALTAGTTKEERELCIESGMDDILSKPYTANDLVIM
LNKWG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=390, Percent_Identity=34.6153846153846, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081816, Length=362, Percent_Identity=32.3204419889503, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=33.3333333333333, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=37.7682403433476, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=39.4957983193277, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=29.957805907173, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=29.6943231441048, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=27.9850746268657, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786912, Length=301, Percent_Identity=25.9136212624585, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=25.3164556962025, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=27.8260869565217, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786783, Length=245, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=29.5454545454545, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=30.5936073059361, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786784, Length=109, Percent_Identity=33.0275229357798, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=26.1603375527426, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=71, Percent_Identity=52.112676056338, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322000, Length=154, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323034, Length=151, Percent_Identity=29.1390728476821, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63303; Mature: 63303

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLASAQEKKLKRQIAARKVAEALLEQKSLELFEANQQLELALRQLEKRSNANIRRIEFQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHH
EQIDNLLIDFGRAFLRSDLDDVMLSQLTASVTNSYLIEASRLVLPPNLIPQLQTHDYGDE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCHH
TVEVIEKDIQEPHWQGCLLTVPLEVEKVIVGALIVQVRLLDQDYEFIQSQLLLVTDLICS
HHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTHQLAINRNIESRKRAEESERATRDFVAMINHELRTPLNGLLGSAELISDTELSNSQR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCCCHH
EIVNNLSQSGEFLRTIINDLLDYSKINAGMLELIPKTFALQDLKNTIDSIFTNRAIEKQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFDVNVTDGVPSHFYGDLERITQLFVNLIGNAIKFTDQGHVSVEIKWLNDQFIFSVEDSG
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCEEEEEEEEECCEEEEEECCCC
VGIAQSAIKTLFEPFTQADNSSSRNYEGTGLGLAICRKLAALMRGDIEVSSIVGSGTTFT
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHEECCCCEEE
ISLPLQVVDTLAERDSVAKGFESEVELTLLKVLVVDDIKMNQIIIQQMLRKYEIEPAIAG
EEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
NGIEGLELASNNEYDIVFMDCRMPVMDGFEATKKLRSSGYSQPIIALTAGTTKEERELCI
CCCCCCEECCCCCEEEEEEECCCCHHCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
ESGMDDILSKPYTANDLVIMLNKWG
HCCCHHHHCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MDLASAQEKKLKRQIAARKVAEALLEQKSLELFEANQQLELALRQLEKRSNANIRRIEFQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHH
EQIDNLLIDFGRAFLRSDLDDVMLSQLTASVTNSYLIEASRLVLPPNLIPQLQTHDYGDE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCHH
TVEVIEKDIQEPHWQGCLLTVPLEVEKVIVGALIVQVRLLDQDYEFIQSQLLLVTDLICS
HHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTHQLAINRNIESRKRAEESERATRDFVAMINHELRTPLNGLLGSAELISDTELSNSQR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCCCHH
EIVNNLSQSGEFLRTIINDLLDYSKINAGMLELIPKTFALQDLKNTIDSIFTNRAIEKQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFDVNVTDGVPSHFYGDLERITQLFVNLIGNAIKFTDQGHVSVEIKWLNDQFIFSVEDSG
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCEEEEEEEEECCEEEEEECCCC
VGIAQSAIKTLFEPFTQADNSSSRNYEGTGLGLAICRKLAALMRGDIEVSSIVGSGTTFT
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHEECCCCEEE
ISLPLQVVDTLAERDSVAKGFESEVELTLLKVLVVDDIKMNQIIIQQMLRKYEIEPAIAG
EEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
NGIEGLELASNNEYDIVFMDCRMPVMDGFEATKKLRSSGYSQPIIALTAGTTKEERELCI
CCCCCCEECCCCCEEEEEEECCCCHHCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
ESGMDDILSKPYTANDLVIMLNKWG
HCCCHHHHCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]