Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 218709717

GI number: 218709717

Start: 1856354

End: 1858303

Strand: Reverse

Name: hlyB [H]

Synonym: VS_1728

Alternate gene names: 218709717

Gene position: 1858303-1856354 (Counterclockwise)

Preceding gene: 218709718

Following gene: 218709715

Centisome position: 56.32

GC content: 46.21

Gene sequence:

>1950_bases
TTGCAAACTGTGTTGGTGACAAATTTGTCACCGCGGTTTTTACTTCCAAATTATAGGTTTCCTATGTTCAAGAAACTCTC
GCTTAAAAATAAGCTGGCGATCTCTGCTAGCATGGCCATTATCCTGGGGGGGATTTTGGTCGAGGTATTGTCTTTTCGTG
CTTCATTGCAACGGTTGGATATTGAAGTTGAACAGCGCTTAGAAGGTGCGTCAGCTTCTTACAATCAATATGTATCGGAT
TGGATCTTATCCAAAGAGCGTGCGCTTACTTCACTTTCGAAGGAGTCACAACAAGAAAGCTTGGTCACTCACCTGAAGCA
GGTTCGTGATTCAGGCTCGTTTGATAATGTGTTCTTAGCGTTCCCTGATGGCTTGCAAAAAAATGCGAATGGCGTAGTGT
TGCCACCGGGCAATGATGATCCACGCGTATGGGGTTGGTACACCAATGCGGTTGCGAACCCAAGTAAGGTGTTCATGGAT
AACCCAACGGTTGCCGCGGCAACTGGGGCGAACGTTGTGTCGTTGGGTACTGCAATGCAACTGCATGGCCAGCAGGTCGT
TTTAGGTGCTGATGTAGAAATTACCGACATTCTAAACAGCCTTGAAAAAGTGATTCTTCCAGGCGAAGGCTACATGTTTA
TCGCGACCAACAAAGGCACGGTTTACACGCACGCTGATACAAAGTTGCTGAATGAGAACATTAGCTCGCTAGGGCTAGAT
TTTTCTGATGTACAGAAGGCACTGACTAGCGGTAAAGACACGGCTATCGAGTTAAATGGCAGCGACTATGTTCTGTACGC
ACGTGCGATTGATGGTACAAGCCTGATTACTATCAGTGTTGTTAATCATGACTCTTTGGTTGCACCGTTATTTGATGCGG
TGATCGGTCAAGTGTTGGTGACACTGTTGGTTGTGATTGTATGTACCATATTGTTTAACCTGCTGTGTACTATTCTGTTC
CGTCCGTTGAACCATGTGTCTCAAGCACTGGCGCAGATCGCTAATGGTAGTGGTGATTTAACTCAGCGTATTCATGTTGA
GAACCAAGATGAAGTAGGAGAACTAGCACAGAACTTCAACACTTTTGTAGGAAGTTTACAGCAGTTGATTGGTCATATTC
GTGGGCAATCAGAGCAGCTTAACAGCCAGTCAGAGAAAAGTACTCAGCGAGCGAATCGTTCGGTGGATGAGCTTAATCAT
CAACAGCAAGAGATCACCATGGTGGCGACGGCTGTAACGGAAATGGCGAGTGCAACGCAAGAGATTGCATCGCATGCTGA
GCAAACAGCAAAAGCGGCACAAGACTCTGCGACAAGCACTAATAGCGGTCACGCCCTGGTTGTCGATACCAAAGGTTCTA
TCAATAACCTTGCCAATGAAGTGAATGAAGCAGGTAATGTGATCAGTGAGCTAAACAAGCATGCTCAAGAGATTTCGACG
GTACTTGCTACGATTCAAGGTATTGCAGAGCAAACTAACTTGCTTGCTTTGAATGCTGCGATTGAAGCGGCGCGTGCTGG
TGAACAAGGTCGTGGTTTTGCTGTAGTTGCAGATGAAGTACGTGTGCTTTCTCAACGAACTCACTCTTCAACAGAAGAGA
TAAAGTCAACGATTGATGTTTTACAACGCACAACGGCTCAAGCGGTTGATCTTATGGAGAGCAGCTCGAAACTGGCAATA
CATTCCGTCGAAGATGCCGACCGAGCTTCACATGCGCTAGAAGAGATCAACACAGCGGTGGCTTTGATTAGTGATATGGC
GACTCAAATTGCTACCGCAGCAGAAGAGCAAACGCACGTGACGGGTGAAATTACTCAGAACATTACGACCATTAAAGATG
TTACGGACCACTTAGTTGTGGGCGCACAGGACAGCTTAACTGAGTCGAACGAACTTAAGAGCCAAGCCGCTGGTTTAAGT
GACAAAGTGGCGACTTTTAAGCTTGCTTAA

Upstream 100 bases:

>100_bases
TTGGTGAATGTCTCGCTATGCGTGCCCCTACTCACATATATTGCTGATATTAACCTTGGATGGTTTATTAATTTATTTTA
AAGCGTAAAATAAATGGTGC

Downstream 100 bases:

>100_bases
CTGTTTCACTCACTGATGCCTGATCAGTGAGTGATTGTTAAGCAATAAGTCAAAGCGACGTAGATTACGTCGCTTTTTTT
GTATTTGTGAGTAATCAAAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MQTVLVTNLSPRFLLPNYRFPMFKKLSLKNKLAISASMAIILGGILVEVLSFRASLQRLDIEVEQRLEGASASYNQYVSD
WILSKERALTSLSKESQQESLVTHLKQVRDSGSFDNVFLAFPDGLQKNANGVVLPPGNDDPRVWGWYTNAVANPSKVFMD
NPTVAAATGANVVSLGTAMQLHGQQVVLGADVEITDILNSLEKVILPGEGYMFIATNKGTVYTHADTKLLNENISSLGLD
FSDVQKALTSGKDTAIELNGSDYVLYARAIDGTSLITISVVNHDSLVAPLFDAVIGQVLVTLLVVIVCTILFNLLCTILF
RPLNHVSQALAQIANGSGDLTQRIHVENQDEVGELAQNFNTFVGSLQQLIGHIRGQSEQLNSQSEKSTQRANRSVDELNH
QQQEITMVATAVTEMASATQEIASHAEQTAKAAQDSATSTNSGHALVVDTKGSINNLANEVNEAGNVISELNKHAQEIST
VLATIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHSSTEEIKSTIDVLQRTTAQAVDLMESSSKLAI
HSVEDADRASHALEEINTAVALISDMATQIATAAEEQTHVTGEITQNITTIKDVTDHLVVGAQDSLTESNELKSQAAGLS
DKVATFKLA

Sequences:

>Translated_649_residues
MQTVLVTNLSPRFLLPNYRFPMFKKLSLKNKLAISASMAIILGGILVEVLSFRASLQRLDIEVEQRLEGASASYNQYVSD
WILSKERALTSLSKESQQESLVTHLKQVRDSGSFDNVFLAFPDGLQKNANGVVLPPGNDDPRVWGWYTNAVANPSKVFMD
NPTVAAATGANVVSLGTAMQLHGQQVVLGADVEITDILNSLEKVILPGEGYMFIATNKGTVYTHADTKLLNENISSLGLD
FSDVQKALTSGKDTAIELNGSDYVLYARAIDGTSLITISVVNHDSLVAPLFDAVIGQVLVTLLVVIVCTILFNLLCTILF
RPLNHVSQALAQIANGSGDLTQRIHVENQDEVGELAQNFNTFVGSLQQLIGHIRGQSEQLNSQSEKSTQRANRSVDELNH
QQQEITMVATAVTEMASATQEIASHAEQTAKAAQDSATSTNSGHALVVDTKGSINNLANEVNEAGNVISELNKHAQEIST
VLATIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHSSTEEIKSTIDVLQRTTAQAVDLMESSSKLAI
HSVEDADRASHALEEINTAVALISDMATQIATAAEEQTHVTGEITQNITTIKDVTDHLVVGAQDSLTESNELKSQAAGLS
DKVATFKLA
>Mature_649_residues
MQTVLVTNLSPRFLLPNYRFPMFKKLSLKNKLAISASMAIILGGILVEVLSFRASLQRLDIEVEQRLEGASASYNQYVSD
WILSKERALTSLSKESQQESLVTHLKQVRDSGSFDNVFLAFPDGLQKNANGVVLPPGNDDPRVWGWYTNAVANPSKVFMD
NPTVAAATGANVVSLGTAMQLHGQQVVLGADVEITDILNSLEKVILPGEGYMFIATNKGTVYTHADTKLLNENISSLGLD
FSDVQKALTSGKDTAIELNGSDYVLYARAIDGTSLITISVVNHDSLVAPLFDAVIGQVLVTLLVVIVCTILFNLLCTILF
RPLNHVSQALAQIANGSGDLTQRIHVENQDEVGELAQNFNTFVGSLQQLIGHIRGQSEQLNSQSEKSTQRANRSVDELNH
QQQEITMVATAVTEMASATQEIASHAEQTAKAAQDSATSTNSGHALVVDTKGSINNLANEVNEAGNVISELNKHAQEIST
VLATIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHSSTEEIKSTIDVLQRTTAQAVDLMESSSKLAI
HSVEDADRASHALEEINTAVALISDMATQIATAAEEQTHVTGEITQNITTIKDVTDHLVVGAQDSLTESNELKSQAAGLS
DKVATFKLA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=31.0541310541311, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI2367378, Length=388, Percent_Identity=29.3814432989691, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788194, Length=353, Percent_Identity=27.1954674220963, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788195, Length=300, Percent_Identity=30.3333333333333, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1789453, Length=365, Percent_Identity=26.5753424657534, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69702; Mature: 69702

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVLVTNLSPRFLLPNYRFPMFKKLSLKNKLAISASMAIILGGILVEVLSFRASLQRLD
CCEEEEECCCCCEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IEVEQRLEGASASYNQYVSDWILSKERALTSLSKESQQESLVTHLKQVRDSGSFDNVFLA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FPDGLQKNANGVVLPPGNDDPRVWGWYTNAVANPSKVFMDNPTVAAATGANVVSLGTAMQ
CCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCEEEECCCCHHHHCHHHH
LHGQQVVLGADVEITDILNSLEKVILPGEGYMFIATNKGTVYTHADTKLLNENISSLGLD
CCCCEEEEECCCHHHHHHHHHHHHEECCCCEEEEEECCCEEEECCHHHHHHCCHHHHCCC
FSDVQKALTSGKDTAIELNGSDYVLYARAIDGTSLITISVVNHDSLVAPLFDAVIGQVLV
HHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHH
TLLVVIVCTILFNLLCTILFRPLNHVSQALAQIANGSGDLTQRIHVENQDEVGELAQNFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHH
TFVGSLQQLIGHIRGQSEQLNSQSEKSTQRANRSVDELNHQQQEITMVATAVTEMASATQ
HHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIASHAEQTAKAAQDSATSTNSGHALVVDTKGSINNLANEVNEAGNVISELNKHAQEIST
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLATIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHSSTEEIKSTIDV
HHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHH
LQRTTAQAVDLMESSSKLAIHSVEDADRASHALEEINTAVALISDMATQIATAAEEQTHV
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGEITQNITTIKDVTDHLVVGAQDSLTESNELKSQAAGLSDKVATFKLA
HHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure
MQTVLVTNLSPRFLLPNYRFPMFKKLSLKNKLAISASMAIILGGILVEVLSFRASLQRLD
CCEEEEECCCCCEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IEVEQRLEGASASYNQYVSDWILSKERALTSLSKESQQESLVTHLKQVRDSGSFDNVFLA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FPDGLQKNANGVVLPPGNDDPRVWGWYTNAVANPSKVFMDNPTVAAATGANVVSLGTAMQ
CCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCEEEECCCCHHHHCHHHH
LHGQQVVLGADVEITDILNSLEKVILPGEGYMFIATNKGTVYTHADTKLLNENISSLGLD
CCCCEEEEECCCHHHHHHHHHHHHEECCCCEEEEEECCCEEEECCHHHHHHCCHHHHCCC
FSDVQKALTSGKDTAIELNGSDYVLYARAIDGTSLITISVVNHDSLVAPLFDAVIGQVLV
HHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHHH
TLLVVIVCTILFNLLCTILFRPLNHVSQALAQIANGSGDLTQRIHVENQDEVGELAQNFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHH
TFVGSLQQLIGHIRGQSEQLNSQSEKSTQRANRSVDELNHQQQEITMVATAVTEMASATQ
HHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIASHAEQTAKAAQDSATSTNSGHALVVDTKGSINNLANEVNEAGNVISELNKHAQEIST
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLATIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSQRTHSSTEEIKSTIDV
HHHHHHHHHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHH
LQRTTAQAVDLMESSSKLAIHSVEDADRASHALEEINTAVALISDMATQIATAAEEQTHV
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGEITQNITTIKDVTDHLVVGAQDSLTESNELKSQAAGLSDKVATFKLA
HHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]