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The map label for this gene is rio2 [H]

Identifier: 218709612

GI number: 218709612

Start: 1738683

End: 1739582

Strand: Reverse

Name: rio2 [H]

Synonym: VS_1622

Alternate gene names: 218709612

Gene position: 1739582-1738683 (Counterclockwise)

Preceding gene: 218709613

Following gene: 218709607

Centisome position: 52.73

GC content: 48.44

Gene sequence:

>900_bases
ATGTATAAAGACGACATGAAGATACCTAAAAGAATACAGCCCTTAGTTGACGATGGTTTAGTCGACGAGGTGACAAGCCA
ATTAATGAGTGGCAAAGAAGCGTCAGTGTACATAGTACGCTGCGGCGATACGATCCGTTGTGCCAAGGTATATAAGGAAA
TAAGCCAGCGCAGCTTTAAAAAAGCAACGGCGTATCGTGAAGGCCGAAAAGTACGTAATAGCCGCCGTGCCAGAGCGATG
GAAAAAGGCTCAGGCTTTGGTCGAGAGCAACAAGAAAAGGTTTGGCAGAGTGCTGAAGTGGATGCCTTATATAAACTGGC
AGAAGCGGGCGTTCGTGTGCCTGTCCCTTATGGTTGCTTTGATGGCGTACTGCTTATGGAACTGGTCACTGACGATGATG
GTTACGTTGCGCCACGTTTGAACGATGTGGTGATGTCAGCAGAGCAAGCGATCGAAGACCACGCTGTGATGATGACCTAC
GTAGTTAAAATGCTGTGTGTTGGTTTGATCCATGGTGACTTGTCTGAGTTCAACGTATTGGTGGATGAATACGGCCCGGT
GATTATCGATTTACCACAAGCGGTTGATGCTTCGGCGAACAACAACGCTGAGTGGATGCTGGCTCGTGACATCAATAACA
TCCGTGAATATTACGCTCAGTTTGCTCCTGAATTGGCGAAAACCGAGTATGCCAAGGAAATGTGGGCGCTGTACGAGAAA
GGCGACTTGAAGCCAGACAGCAAGCTAACGGGTGAGTTTACGGAAACGGACGACTTGGCGGATATCGAAGCCATCATGCA
AGAGATAGACGCTGCGCGAATTGAAGAGCAACACCGACGCGAGCGAGCTAAAGAAGAGAAAGAAGGTGTCGACGACAGTA
AGTTCAATTGGGCTGAGTAA

Upstream 100 bases:

>100_bases
GTCGCCATAAGACAAAACCCACATAATCTCCCTTCATTTAAGAATCTATTGAGAATAACCACTCATTTAACGAGTTAATA
TTTTATCTGTCAGGTAACTC

Downstream 100 bases:

>100_bases
TCGTAATGATCTGTTTTGATCTTTCGTAAATGTCAGTCATAACGCCTTAAAAAACTAAGGCGCTCTTTCAAAAAAATAAC
CCAATAGAGCTTCAACTCTG

Product: RIO1 family protein

Products: NA

Alternate protein names: AfRio2 [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MYKDDMKIPKRIQPLVDDGLVDEVTSQLMSGKEASVYIVRCGDTIRCAKVYKEISQRSFKKATAYREGRKVRNSRRARAM
EKGSGFGREQQEKVWQSAEVDALYKLAEAGVRVPVPYGCFDGVLLMELVTDDDGYVAPRLNDVVMSAEQAIEDHAVMMTY
VVKMLCVGLIHGDLSEFNVLVDEYGPVIIDLPQAVDASANNNAEWMLARDINNIREYYAQFAPELAKTEYAKEMWALYEK
GDLKPDSKLTGEFTETDDLADIEAIMQEIDAARIEEQHRRERAKEEKEGVDDSKFNWAE

Sequences:

>Translated_299_residues
MYKDDMKIPKRIQPLVDDGLVDEVTSQLMSGKEASVYIVRCGDTIRCAKVYKEISQRSFKKATAYREGRKVRNSRRARAM
EKGSGFGREQQEKVWQSAEVDALYKLAEAGVRVPVPYGCFDGVLLMELVTDDDGYVAPRLNDVVMSAEQAIEDHAVMMTY
VVKMLCVGLIHGDLSEFNVLVDEYGPVIIDLPQAVDASANNNAEWMLARDINNIREYYAQFAPELAKTEYAKEMWALYEK
GDLKPDSKLTGEFTETDDLADIEAIMQEIDAARIEEQHRRERAKEEKEGVDDSKFNWAE
>Mature_299_residues
MYKDDMKIPKRIQPLVDDGLVDEVTSQLMSGKEASVYIVRCGDTIRCAKVYKEISQRSFKKATAYREGRKVRNSRRARAM
EKGSGFGREQQEKVWQSAEVDALYKLAEAGVRVPVPYGCFDGVLLMELVTDDDGYVAPRLNDVVMSAEQAIEDHAVMMTY
VVKMLCVGLIHGDLSEFNVLVDEYGPVIIDLPQAVDASANNNAEWMLARDINNIREYYAQFAPELAKTEYAKEMWALYEK
GDLKPDSKLTGEFTETDDLADIEAIMQEIDAARIEEQHRRERAKEEKEGVDDSKFNWAE

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI229331971, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI229331967, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI23510356, Length=206, Percent_Identity=29.6116504854369, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115532073, Length=214, Percent_Identity=29.4392523364486, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324693, Length=240, Percent_Identity=25.8333333333333, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662811, Length=216, Percent_Identity=30.0925925925926, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356879, Length=216, Percent_Identity=30.0925925925926, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24649986, Length=209, Percent_Identity=28.2296650717703, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR018934
- InterPro:   IPR015285
- InterPro:   IPR000687
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1; PF09202 Rio2_N [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33960; Mature: 33960

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDDMKIPKRIQPLVDDGLVDEVTSQLMSGKEASVYIVRCGDTIRCAKVYKEISQRSFK
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
KATAYREGRKVRNSRRARAMEKGSGFGREQQEKVWQSAEVDALYKLAEAGVRVPVPYGCF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DGVLLMELVTDDDGYVAPRLNDVVMSAEQAIEDHAVMMTYVVKMLCVGLIHGDLSEFNVL
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VDEYGPVIIDLPQAVDASANNNAEWMLARDINNIREYYAQFAPELAKTEYAKEMWALYEK
HHCCCCEEEECCCHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLKPDSKLTGEFTETDDLADIEAIMQEIDAARIEEQHRRERAKEEKEGVDDSKFNWAE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MYKDDMKIPKRIQPLVDDGLVDEVTSQLMSGKEASVYIVRCGDTIRCAKVYKEISQRSFK
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
KATAYREGRKVRNSRRARAMEKGSGFGREQQEKVWQSAEVDALYKLAEAGVRVPVPYGCF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DGVLLMELVTDDDGYVAPRLNDVVMSAEQAIEDHAVMMTYVVKMLCVGLIHGDLSEFNVL
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VDEYGPVIIDLPQAVDASANNNAEWMLARDINNIREYYAQFAPELAKTEYAKEMWALYEK
HHCCCCEEEECCCHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLKPDSKLTGEFTETDDLADIEAIMQEIDAARIEEQHRRERAKEEKEGVDDSKFNWAE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]