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The map label for this gene is potC [H]

Identifier: 218709467

GI number: 218709467

Start: 1607743

End: 1608513

Strand: Direct

Name: potC [H]

Synonym: VS_1476

Alternate gene names: 218709467

Gene position: 1607743-1608513 (Clockwise)

Preceding gene: 218709466

Following gene: 218709468

Centisome position: 48.73

GC content: 44.62

Gene sequence:

>771_bases
ATGGGTCGCACAGTTAAGTTCAGCTTTATGGCGTTGGTATACGCTTTTCTATACCTACCTATTATCGTATTGATTGCAAA
CTCATTTAATGCCAATAAATTCGGCATGAAATGGGGTGGCTTTACCACCAAGTGGTATGACGCGCTGATTAACAACGACA
GCCTAATGCAGGCTGCGTGGCATTCGATCAACGTAGCGGTGTTCTCAGCGACTGCCGCAACGATTGTCGGAAGCCTGACT
GCCGTTGCCCTATTCCGTTACCAATTTAAAGGTAAAGGCATCGTCAATGGCATGTTGTTCATCGTGATGATGTCACCAGA
TATCGTAATGGCGATTTCGCTTCTTGCGCTATTCTTGGTTATGGGTGTACAACTTGGGTTCTTTACCCTACTTGCAGCGC
ACATTACTTTCTGTTTACCGTTCGTTGTTGTCACGGTCTACAGCCGCTTAAATGGCTTTGATGTGAAGATGCTAGAAGCA
GCAAAAGACTTAGGTGCAAGTGAATGGACGATTCTAAAGCAGATCATTCTACCTCTTGCTAAGCCAGCGGTTGCTGCGGG
TTGGTTATTGAGCTTCACTCTGTCTTTGGACGATGTGATCATCAGCTCTTTCGTAACCGGCCCAACGTATGAAATCTTAC
CACTGAAGATTTACTCAATGGTTAAAGTGGGTATCTCTCCTGAGGTAAACGCCCTAGCAACAGTGATGTTAGTGGTGTCG
TTAATACTGGTGATCATTTCTCAGTTATTAGCGAGAGAAAAAATCAAGTAA

Upstream 100 bases:

>100_bases
GCGCTGCGACGAGTATTGCACTGACCGTGGCAATGGCTGTGATGCTTTATGCCTACTACCGTGCAGGTAAGTTATTGAAT
AAGAAAGTGGAGCTAGACTA

Downstream 100 bases:

>100_bases
GTCTCCTACTCTATATTAGAGACAGGCTTGATTAAGAAGTTAAGAGACTTCAAGTTCAAAAAAGTGTTAATCATAAACAG
AATGGTAAATTGCCATTCTG

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGRTVKFSFMALVYAFLYLPIIVLIANSFNANKFGMKWGGFTTKWYDALINNDSLMQAAWHSINVAVFSATAATIVGSLT
AVALFRYQFKGKGIVNGMLFIVMMSPDIVMAISLLALFLVMGVQLGFFTLLAAHITFCLPFVVVTVYSRLNGFDVKMLEA
AKDLGASEWTILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
LILVIISQLLAREKIK

Sequences:

>Translated_256_residues
MGRTVKFSFMALVYAFLYLPIIVLIANSFNANKFGMKWGGFTTKWYDALINNDSLMQAAWHSINVAVFSATAATIVGSLT
AVALFRYQFKGKGIVNGMLFIVMMSPDIVMAISLLALFLVMGVQLGFFTLLAAHITFCLPFVVVTVYSRLNGFDVKMLEA
AKDLGASEWTILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
LILVIISQLLAREKIK
>Mature_255_residues
GRTVKFSFMALVYAFLYLPIIVLIANSFNANKFGMKWGGFTTKWYDALINNDSLMQAAWHSINVAVFSATAATIVGSLTA
VALFRYQFKGKGIVNGMLFIVMMSPDIVMAISLLALFLVMGVQLGFFTLLAAHITFCLPFVVVTVYSRLNGFDVKMLEAA
KDLGASEWTILKQIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVSL
ILVIISQLLAREKIK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=256, Percent_Identity=73.828125, Blast_Score=382, Evalue=1e-108,
Organism=Escherichia coli, GI1787081, Length=254, Percent_Identity=40.5511811023622, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1787714, Length=241, Percent_Identity=30.2904564315353, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788764, Length=210, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28005; Mature: 27874

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRTVKFSFMALVYAFLYLPIIVLIANSFNANKFGMKWGGFTTKWYDALINNDSLMQAAW
CCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
HSINVAVFSATAATIVGSLTAVALFRYQFKGKGIVNGMLFIVMMSPDIVMAISLLALFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCHHHHHHHHHHHHHH
MGVQLGFFTLLAAHITFCLPFVVVTVYSRLNGFDVKMLEAAKDLGASEWTILKQIILPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
KPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LILVIISQLLAREKIK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRTVKFSFMALVYAFLYLPIIVLIANSFNANKFGMKWGGFTTKWYDALINNDSLMQAAW
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
HSINVAVFSATAATIVGSLTAVALFRYQFKGKGIVNGMLFIVMMSPDIVMAISLLALFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEECCHHHHHHHHHHHHHH
MGVQLGFFTLLAAHITFCLPFVVVTVYSRLNGFDVKMLEAAKDLGASEWTILKQIILPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
KPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LILVIISQLLAREKIK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]