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The map label for this gene is uspE [H]

Identifier: 218709459

GI number: 218709459

Start: 1600588

End: 1601538

Strand: Direct

Name: uspE [H]

Synonym: VS_1468

Alternate gene names: 218709459

Gene position: 1600588-1601538 (Clockwise)

Preceding gene: 218709458

Following gene: 218709465

Centisome position: 48.51

GC content: 44.27

Gene sequence:

>951_bases
ATGAGTATCTATAACAAAATTTTAGTTGTCGCAGACATTAATCACGATGAGCAACCTGCTCTAGTTCGTGCTATCCAACT
TGCCAAGAAAAGCACATCAACAAGCCACATCACTTTCTTTTTATCGATCTACGATTTCTCGTATGACATGACATCTATGC
TCTCTGTCGATGAAAGAGACGCAATGCGTAAAGGCGTAATTCATCAACGTGAAATTTGGATGAATAAAGTGGCGGCTCCT
TACCTTGATGATTCTATTGAATTTAACGTGCAAGTGGTTTGGCATAACCGCCCGTATGAAGCGATCATTGCAGAGGTTTA
CAGTGGCGAGCATGACATTCTAATCAAAGGTACGCGTAAGCACGATACCTTAGAATCTGTCATCTTTACTCCTACCGACT
GGCACTTATTGAGAAAATGCCCTAGCCCAGTGCTATTGGTTAAAAATGATTTCTGGCCAGAACACGCGAAGATTTACGCT
TCAGTTCATGTAGGCTCTGAAACCGAAGCTCACTTAGAGCTCAATGATGCGATGGTCGACAGGTTGCTTGAAATCACAGG
TCGTTTAGATGCTGAGCCGCTATTGGTAAACGCCTACCCGGTGACACCTGCTAATATCACAATCGAGCTGCCAGAGTTTG
ACCCAACCTCTTATACTGACGCGGTTCGTGGTCATCACTTAACAGCGATGAAAGCGTTGCGCCAGAAACACGGTATGAGT
GAAGAGCAAACTGTTGTTGAGCAAGGCTTGCCAGAAGATGTTATTCCTCGTGTCGCGTCTGAAAACAACGCTGCTATGGT
GATTCTTGGTACAACCGGCCGTACTGGATTGTCTGCTGTGTTTATTGGTAATACTGCGGAACATGTAATCGACAAGATTA
ACTGTGACGTACTTGCTCTTAAACCGTCGGGTTACGTCAGTCCACTTGATCCCAATTTGTCTATAGGTTAA

Upstream 100 bases:

>100_bases
CTACATCATGTTTCTCTCTTAAAACCTCTTATATTTCTCTTATTCTCTCCATAACTACGCTACATTATTTATATGTTCGG
TCTGAAAAGTAGGCTTAGTT

Downstream 100 bases:

>100_bases
TACCTTATAGCTGATTTAAAATCATAAAAAAACGCCTCAAGCACTGCTTGAGGCGTTTTTATTTATCTAGAGCTTCCGCC
ATTCCAAATACAGAATCGCG

Product: universal stress protein UspE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSIYNKILVVADINHDEQPALVRAIQLAKKSTSTSHITFFLSIYDFSYDMTSMLSVDERDAMRKGVIHQREIWMNKVAAP
YLDDSIEFNVQVVWHNRPYEAIIAEVYSGEHDILIKGTRKHDTLESVIFTPTDWHLLRKCPSPVLLVKNDFWPEHAKIYA
SVHVGSETEAHLELNDAMVDRLLEITGRLDAEPLLVNAYPVTPANITIELPEFDPTSYTDAVRGHHLTAMKALRQKHGMS
EEQTVVEQGLPEDVIPRVASENNAAMVILGTTGRTGLSAVFIGNTAEHVIDKINCDVLALKPSGYVSPLDPNLSIG

Sequences:

>Translated_316_residues
MSIYNKILVVADINHDEQPALVRAIQLAKKSTSTSHITFFLSIYDFSYDMTSMLSVDERDAMRKGVIHQREIWMNKVAAP
YLDDSIEFNVQVVWHNRPYEAIIAEVYSGEHDILIKGTRKHDTLESVIFTPTDWHLLRKCPSPVLLVKNDFWPEHAKIYA
SVHVGSETEAHLELNDAMVDRLLEITGRLDAEPLLVNAYPVTPANITIELPEFDPTSYTDAVRGHHLTAMKALRQKHGMS
EEQTVVEQGLPEDVIPRVASENNAAMVILGTTGRTGLSAVFIGNTAEHVIDKINCDVLALKPSGYVSPLDPNLSIG
>Mature_315_residues
SIYNKILVVADINHDEQPALVRAIQLAKKSTSTSHITFFLSIYDFSYDMTSMLSVDERDAMRKGVIHQREIWMNKVAAPY
LDDSIEFNVQVVWHNRPYEAIIAEVYSGEHDILIKGTRKHDTLESVIFTPTDWHLLRKCPSPVLLVKNDFWPEHAKIYAS
VHVGSETEAHLELNDAMVDRLLEITGRLDAEPLLVNAYPVTPANITIELPEFDPTSYTDAVRGHHLTAMKALRQKHGMSE
EQTVVEQGLPEDVIPRVASENNAAMVILGTTGRTGLSAVFIGNTAEHVIDKINCDVLALKPSGYVSPLDPNLSIG

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1787594, Length=311, Percent_Identity=54.983922829582, Blast_Score=352, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 35307; Mature: 35175

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYNKILVVADINHDEQPALVRAIQLAKKSTSTSHITFFLSIYDFSYDMTSMLSVDERD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHCCCHHH
AMRKGVIHQREIWMNKVAAPYLDDSIEFNVQVVWHNRPYEAIIAEVYSGEHDILIKGTRK
HHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCC
HDTLESVIFTPTDWHLLRKCPSPVLLVKNDFWPEHAKIYASVHVGSETEAHLELNDAMVD
CCCHHHEEECCCCHHHHHHCCCCEEEEECCCCCCCEEEEEEEEECCCCCEEEEEHHHHHH
RLLEITGRLDAEPLLVNAYPVTPANITIELPEFDPTSYTDAVRGHHLTAMKALRQKHGMS
HHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHCCC
EEQTVVEQGLPEDVIPRVASENNAAMVILGTTGRTGLSAVFIGNTAEHVIDKINCDVLAL
HHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHCCCCEEEE
KPSGYVSPLDPNLSIG
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIYNKILVVADINHDEQPALVRAIQLAKKSTSTSHITFFLSIYDFSYDMTSMLSVDERD
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHCCCHHH
AMRKGVIHQREIWMNKVAAPYLDDSIEFNVQVVWHNRPYEAIIAEVYSGEHDILIKGTRK
HHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCC
HDTLESVIFTPTDWHLLRKCPSPVLLVKNDFWPEHAKIYASVHVGSETEAHLELNDAMVD
CCCHHHEEECCCCHHHHHHCCCCEEEEECCCCCCCEEEEEEEEECCCCCEEEEEHHHHHH
RLLEITGRLDAEPLLVNAYPVTPANITIELPEFDPTSYTDAVRGHHLTAMKALRQKHGMS
HHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHCCC
EEQTVVEQGLPEDVIPRVASENNAAMVILGTTGRTGLSAVFIGNTAEHVIDKINCDVLAL
HHHHHHHCCCCHHHHHHHCCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHCCCCEEEE
KPSGYVSPLDPNLSIG
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]