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The map label for this gene is aroH [H]

Identifier: 218709397

GI number: 218709397

Start: 1536620

End: 1537678

Strand: Reverse

Name: aroH [H]

Synonym: VS_1406

Alternate gene names: 218709397

Gene position: 1537678-1536620 (Counterclockwise)

Preceding gene: 218709400

Following gene: 218709396

Centisome position: 46.61

GC content: 44.76

Gene sequence:

>1059_bases
ATGCCATTAAAAACTGATGAGTTGAGAACCCAAGCTCTGGGTCCTATGCCAACTCCTGCCGAACTAGGCAATGCACACCC
TATTACTGACGACGTTGCTGAGCGCATTAAGAATTCTCGCCGCCAAATCGAAGATATCCTAACGGGTCGTGATAATCGCC
TATTAGTTATCGTTGGTCCTTGCTCTGTTCACGATACAGATGCGGCACTTGATTACGCTGAACGTCTAAGCCAGATTCAA
GATCAATACAAAGATGAACTATTCGTTGTCATGAGAACCTACTTCGAGAAACCTCGTACGGTTGTAGGTTGGAAAGGTTT
AATTACCGATCCGAATCTCGATGGTTCATACGCACTTGAAACAGGCTTGAATAAAGCACGTAAGCTATTGCTAGATATCA
ACAAGCTTGGCCTAGCTACCGCGACTGAATTCCTTGATATGATCACCGGTCAGTACATTGCAGACCTTATCACTTGGGGC
GCAATTGGCGCTCGCACTACTGAATCTCAGATTCACCGTGAAATGGCTTCTGCACTGTCTTGCCCAGTTGGCTTCAAAAA
CGCAACTAACGGCAACATCAAAATTGCCATTGATGCGATTCGTGCTGCGCATGCTTCACACTACTTCTACTCTCCAGATA
AGAACGGTCGCATGACGGTTTACCGTACTTCTGGTAACCCATACGGTCACGTAATTCTACGTGGTGGCGATAAAGGCCCT
AACTTCGATGCTGAATCTGTGGATAACGCATGTAAGCAGTTGGCTGAATTCGATCTGCCTCAACGTTTAGTTGTAGACTT
TAGCCACGCTAACTGTCAAAAACAGCACCGTAAGCAGCTAGAAGTAGCGCAAGACATTTGTGAACAAATCAAATCTAACA
AGAATCAAATTGCAGGCATCATGGCGGAAAGCTTCATTGTTGAAGGTAACCAGCCAATGACAGATATCAACAACCTAGAA
TACGGCAAGTCTATTACTGATCCATGCCTAAGCTGGGAAGATACTGCGACAATGCTCGATATGCTTGCAACAGCAATTAA
AGATAGAAACTTAGCTTAA

Upstream 100 bases:

>100_bases
ATATTAGCAATAACAGAGATAACTTTGACTTAAGAGAGTTTATTCCTCTGTTCAATTCCGTTATCTTAACCACTTCGCAA
TAGAATAAAAAAGCTATCAC

Downstream 100 bases:

>100_bases
GGAAACAACACAATGCCATCATTTGACATTATCTCTGAAGTAGAAGCAGTAGAACTGCGTAACGCGGTAGACAACGCAAA
CCGTGAACTATCGACTCGTT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MPLKTDELRTQALGPMPTPAELGNAHPITDDVAERIKNSRRQIEDILTGRDNRLLVIVGPCSVHDTDAALDYAERLSQIQ
DQYKDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALETGLNKARKLLLDINKLGLATATEFLDMITGQYIADLITWG
AIGARTTESQIHREMASALSCPVGFKNATNGNIKIAIDAIRAAHASHYFYSPDKNGRMTVYRTSGNPYGHVILRGGDKGP
NFDAESVDNACKQLAEFDLPQRLVVDFSHANCQKQHRKQLEVAQDICEQIKSNKNQIAGIMAESFIVEGNQPMTDINNLE
YGKSITDPCLSWEDTATMLDMLATAIKDRNLA

Sequences:

>Translated_352_residues
MPLKTDELRTQALGPMPTPAELGNAHPITDDVAERIKNSRRQIEDILTGRDNRLLVIVGPCSVHDTDAALDYAERLSQIQ
DQYKDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALETGLNKARKLLLDINKLGLATATEFLDMITGQYIADLITWG
AIGARTTESQIHREMASALSCPVGFKNATNGNIKIAIDAIRAAHASHYFYSPDKNGRMTVYRTSGNPYGHVILRGGDKGP
NFDAESVDNACKQLAEFDLPQRLVVDFSHANCQKQHRKQLEVAQDICEQIKSNKNQIAGIMAESFIVEGNQPMTDINNLE
YGKSITDPCLSWEDTATMLDMLATAIKDRNLA
>Mature_351_residues
PLKTDELRTQALGPMPTPAELGNAHPITDDVAERIKNSRRQIEDILTGRDNRLLVIVGPCSVHDTDAALDYAERLSQIQD
QYKDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALETGLNKARKLLLDINKLGLATATEFLDMITGQYIADLITWGA
IGARTTESQIHREMASALSCPVGFKNATNGNIKIAIDAIRAAHASHYFYSPDKNGRMTVYRTSGNPYGHVILRGGDKGPN
FDAESVDNACKQLAEFDLPQRLVVDFSHANCQKQHRKQLEVAQDICEQIKSNKNQIAGIMAESFIVEGNQPMTDINNLEY
GKSITDPCLSWEDTATMLDMLATAIKDRNLA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=65.3179190751445, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1786969, Length=349, Percent_Identity=53.5816618911175, Blast_Score=383, Evalue=1e-108,
Organism=Escherichia coli, GI1788953, Length=323, Percent_Identity=50.1547987616099, Blast_Score=327, Evalue=5e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=346, Percent_Identity=47.6878612716763, Blast_Score=332, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6320240, Length=356, Percent_Identity=42.9775280898876, Blast_Score=306, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39056; Mature: 38925

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKTDELRTQALGPMPTPAELGNAHPITDDVAERIKNSRRQIEDILTGRDNRLLVIVGP
CCCCHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
CSVHDTDAALDYAERLSQIQDQYKDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCCCCCHHHH
TGLNKARKLLLDINKLGLATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
CPVGFKNATNGNIKIAIDAIRAAHASHYFYSPDKNGRMTVYRTSGNPYGHVILRGGDKGP
CCCCCCCCCCCCEEEEEHHHHHHHHHCCEECCCCCCCEEEEEECCCCEEEEEEECCCCCC
NFDAESVDNACKQLAEFDLPQRLVVDFSHANCQKQHRKQLEVAQDICEQIKSNKNQIAGI
CCCHHHHHHHHHHHHHCCCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
MAESFIVEGNQPMTDINNLEYGKSITDPCLSWEDTATMLDMLATAIKDRNLA
HHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLKTDELRTQALGPMPTPAELGNAHPITDDVAERIKNSRRQIEDILTGRDNRLLVIVGP
CCCHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
CSVHDTDAALDYAERLSQIQDQYKDELFVVMRTYFEKPRTVVGWKGLITDPNLDGSYALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCCCCCHHHH
TGLNKARKLLLDINKLGLATATEFLDMITGQYIADLITWGAIGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
CPVGFKNATNGNIKIAIDAIRAAHASHYFYSPDKNGRMTVYRTSGNPYGHVILRGGDKGP
CCCCCCCCCCCCEEEEEHHHHHHHHHCCEECCCCCCCEEEEEECCCCEEEEEEECCCCCC
NFDAESVDNACKQLAEFDLPQRLVVDFSHANCQKQHRKQLEVAQDICEQIKSNKNQIAGI
CCCHHHHHHHHHHHHHCCCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
MAESFIVEGNQPMTDINNLEYGKSITDPCLSWEDTATMLDMLATAIKDRNLA
HHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]