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The map label for this gene is queC [H]

Identifier: 218709346

GI number: 218709346

Start: 1466693

End: 1467349

Strand: Reverse

Name: queC [H]

Synonym: VS_1355

Alternate gene names: 218709346

Gene position: 1467349-1466693 (Counterclockwise)

Preceding gene: 218709347

Following gene: 218709343

Centisome position: 44.47

GC content: 38.51

Gene sequence:

>657_bases
ATGCAACAGTCAAAAGCGCTTGTAGTGTTTTCAGGTGGGCAAGATTCTACCACCTGCCTAATCGATGCATTAAATACATA
TGATGAAGTTCATGCGATAACATTCGATTATGGACAACGTCATTCAAATGAAATTGATGTTGCCGTCAGTATAGGTAAGG
AACTTAATGTAAAAAGCCATAAAGTTCTCGATGTAACTGCAATCAACGAGTTAGCGATAAGCTCTCTCACTAGAGATAAT
ATTCCAGTGTCAAATGAGCTGAGCAACAATGATCTACCAAACACATTCGTACCTGGGAGAAATATTGTCTTTCTTACTTA
TGCTTGTATCCACGCTTATCAACTTGGTATTAAAGATATAGTAACTGGTGTTTGTGAAACTGACTTCTCTGGCTACCCAG
ACTGCCGTGATACTTTTATTCGTGCACTTAACTTATCTTGTAATTTGGGAATGGATAATGCGTTTAATATAAAGACGCCT
TTAATGTGGCTAAATAAGGCTGAGACTTGGGAGTTAGCTGATAAGCACAATAAGTTAGAGTACGTAGAAAAAAACACATT
AACTTGCTACAACGGGATTTTAGGCAAGGGTTGCGGCGAATGCCCTGCTTGTCTATTAAGACAGAATGGCCTGAAAGAGT
ACTTAGCTAGTAAGTGA

Upstream 100 bases:

>100_bases
TTATGAAGTTGAACCTAATTAATCTAAATGGCCTTAAGCTCACTGCCGCCCACAATTTTAGACATTAATTCAGTAACTTA
ATTTTTAACAAGGATATATC

Downstream 100 bases:

>100_bases
TATTTTCAAAGTTTGGGAAGAGGGTATTGAAATAAAAATTTGTCAAAATTTGTTTTTCCAAATTTCAGTGTCAACAAGGC
GTTAAATTGATTGTCAACGA

Product: queuosine biosynthesis protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MQQSKALVVFSGGQDSTTCLIDALNTYDEVHAITFDYGQRHSNEIDVAVSIGKELNVKSHKVLDVTAINELAISSLTRDN
IPVSNELSNNDLPNTFVPGRNIVFLTYACIHAYQLGIKDIVTGVCETDFSGYPDCRDTFIRALNLSCNLGMDNAFNIKTP
LMWLNKAETWELADKHNKLEYVEKNTLTCYNGILGKGCGECPACLLRQNGLKEYLASK

Sequences:

>Translated_218_residues
MQQSKALVVFSGGQDSTTCLIDALNTYDEVHAITFDYGQRHSNEIDVAVSIGKELNVKSHKVLDVTAINELAISSLTRDN
IPVSNELSNNDLPNTFVPGRNIVFLTYACIHAYQLGIKDIVTGVCETDFSGYPDCRDTFIRALNLSCNLGMDNAFNIKTP
LMWLNKAETWELADKHNKLEYVEKNTLTCYNGILGKGCGECPACLLRQNGLKEYLASK
>Mature_218_residues
MQQSKALVVFSGGQDSTTCLIDALNTYDEVHAITFDYGQRHSNEIDVAVSIGKELNVKSHKVLDVTAINELAISSLTRDN
IPVSNELSNNDLPNTFVPGRNIVFLTYACIHAYQLGIKDIVTGVCETDFSGYPDCRDTFIRALNLSCNLGMDNAFNIKTP
LMWLNKAETWELADKHNKLEYVEKNTLTCYNGILGKGCGECPACLLRQNGLKEYLASK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=215, Percent_Identity=63.2558139534884, Blast_Score=293, Evalue=8e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24148; Mature: 24148

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSKALVVFSGGQDSTTCLIDALNTYDEVHAITFDYGQRHSNEIDVAVSIGKELNVKSH
CCCCCEEEEEECCCCCCEEEEEHHHCHHHHEEEEECCCCCCCCCEEEEEEECCCCCCCCC
KVLDVTAINELAISSLTRDNIPVSNELSNNDLPNTFVPGRNIVFLTYACIHAYQLGIKDI
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHH
VTGVCETDFSGYPDCRDTFIRALNLSCNLGMDNAFNIKTPLMWLNKAETWELADKHNKLE
HHHHHCCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCEEECCCCCCCHHHHHCCCEE
YVEKNTLTCYNGILGKGCGECPACLLRQNGLKEYLASK
EHHCCCEEEHHCCCCCCCCHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MQQSKALVVFSGGQDSTTCLIDALNTYDEVHAITFDYGQRHSNEIDVAVSIGKELNVKSH
CCCCCEEEEEECCCCCCEEEEEHHHCHHHHEEEEECCCCCCCCCEEEEEEECCCCCCCCC
KVLDVTAINELAISSLTRDNIPVSNELSNNDLPNTFVPGRNIVFLTYACIHAYQLGIKDI
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHH
VTGVCETDFSGYPDCRDTFIRALNLSCNLGMDNAFNIKTPLMWLNKAETWELADKHNKLE
HHHHHCCCCCCCCCHHHHHHHHHCCEEECCCCCCCCCCCCEEECCCCCCCHHHHHCCCEE
YVEKNTLTCYNGILGKGCGECPACLLRQNGLKEYLASK
EHHCCCEEEHHCCCCCCCCHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA