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The map label for this gene is clpV1 [H]

Identifier: 218709317

GI number: 218709317

Start: 1431277

End: 1433889

Strand: Reverse

Name: clpV1 [H]

Synonym: VS_1326

Alternate gene names: 218709317

Gene position: 1433889-1431277 (Counterclockwise)

Preceding gene: 218709318

Following gene: 218709316

Centisome position: 43.46

GC content: 45.39

Gene sequence:

>2613_bases
ATGACACAAGTAACGCTCACTAACTTAGTAGGCAAGCTAGCACCTGCCCTAAAGCAGGCGCTCGAAGCATCTGCTGGTTC
AGCAATGAACCAAGGTGTTGGAGCTATAGAGGTTGAACACTGGATTCTTCAACTTATCTCCCAGAAAGACCCAATGCTCA
TGACATTGTGTGAATCTCAGAAACTTTCAATAGATGCCTTAGTCAGTGAATTGACAAAGAAAATCTCTATGCTCCCAAAA
GGTAATGAAGGTCAACCGACGTTAAGCCACGGCTTAACGGAATTAATCAAAGACGCTTGGATGATTGCTTCAGTTAACTA
CGGGCATGGAGAGATCGTCAGCCTACACCTTATTCAAGCTCTAATGCAGCAAAATGTATTAGGTGTGACGACCTTACAAC
TTGAATCATTAAGCAATGTTTCACTTGAGTCTCTGCAAGGTCTTATCAAGAAAACTCCTATTGCACGTAACTCTTCAGCA
CCTTCAGCTAATGGCGCTGTCGATAGTACCCCCGCGGGTAACGACGCTCTAAGCAAATACACGGTAAACCTTACTCAGCA
GGCTATTGATGGCAACATCGACCCAATTTCAGGCCGTAATGCAGAAGTAAGAAAAGCGATTGACATCTTGTGTCGTAAGC
GCCAAAACAACCCGATTATGGTCGGTGAACCAGGCGTAGGTAAAACTGCTGTTGTTGAAGGATTAGCGTTAAGAATTGCA
GCCGATGAAGTCCCTAGTGCTCTACAAGGCGTACAGATCCACTCTTTAGACCTTGGCTTGCTGCAAGCCGGCGCGAGCGT
TAAAGGTGAGTTTGAAAACCGCTTAAAAGACGTCATCAATGAAGTAAAAAGCTCAGAAGTACCCATCATTGTATTTATCG
ATGAAGCTCACACCCTTATTGGTGCAGGCGGCGCTGCTGGACAAAACGACGCGGCAAACCTTCTAAAACCAGCCCTGGCG
CGTGGTGAGTTCAAAACCATCGCTGCGACAACATGGGCGGAATACAAAAAGTACTTCGAAAAAGATCCGGCTCTAACACG
CCGATTCCAAGTTGTGACCATTGAAGAGCCTAACGCAGAAGATGCGATGCAAATGCTTCGTGGTGTGGCTGCTTCATTGC
AAGCTCACCATGGCGCTTTTATTGCTGAATCCGCGATTGAAGCAGCGGTCAACTTATCGATCCGTTACCTTCCAAGTCGC
CAACTGCCAGACAAAGCCATTAGCCTACTTGATACTGCCAGTGCACGAATCGCACTGACACAAGGCGCGAAGCCAGAAGT
ATTGGAAACACTAGAGCAGACGATTCGTTATCAAGAAAACGAAAAATCAGCATTAGAAAAAGAAGAGGCACTGTTCTCCA
ACAGCGCTGAGTTGATTAAAGAGCTCACACTATCGATAGAAGAGAACCAACAAACGTTGGCTGCGTATTACACGCGTTGG
GAAAAAGAGATTGAATTAGTAGACCAAATTAAAGTGATTCAGCAAGAGATAACTGAAGCACAAGAGCTAAATGCGGTTGA
CTCCAACAAGCAGCAACAACTCGACGGCCTACGTATCGAGTTAGCAAACGTACAAGGTGAGGAGCCCCTCGTCTATGCCA
TGGTCGACGATAACACTATTGCTCAGGTGATTGCGAATTGGACTGGTATCCCGGTTGGTAACATGATGAGCGATGAAATC
GCTAAGCTGCTGACCTTGGAAGATGAACTTAATACTCGAGTAATAGGACAAGATGTCGCAAAGAACGAACTAGCAAAAGC
AATTCGTATTTCCCGAGCGGGTTTAACGGATAATCGAAAACCGATTGGTGTGTTCCTAATGTGTGGTCCAAGTGGTGTCG
GTAAAACTGAAACTGCCATGGCACTTGCGGAGCAACTGTACGGAGGAAGCAACGATCTTACTGTTATTAACATGACCGAG
TTTAAAGAGGAGCATAAAATTTCCATGCTACTCGGCTCACCAGCAGGTTACGTGGGCTTTGGCGAAGGTGGTGTATTGAC
GGAAGCGATTCGACGCAACCCTTATTCTGTATTGCTATTGGATGAGATGGAGAAGGCTCACCCTGGCGTACATGATCTGT
TCTATCAAATCTTCGATAAAGGTCATATCAAAGACAGCGAAGGTCGAACCGTCGATTTCAAGAACACCATCATTATTATG
ACGTCGAACGCTGCCGACCAAGCTATCTGTGACGTGTGTGCTCAGACTACCGATCGCATCGATAATGACAAGCTACTCGA
ATCAATACGTCCGGATCTGCAACAATACTTTAAACCTGCATTTTTAGGCCGAACTACCATTGTTCCCTACTACCCACTTA
ACGATGAAGAATTAGCGAAAATCACAGAAATATCGCTAAATCGAATCAAAAAGAAACTTGCAGAGCAATATAAGGCATCA
TTCACTTGGGATACGAATTTCATTCAGTTCGTGGTCGACCGTAATACCGATCCAACCACTGGCGGTCGCGCTGTAGAACA
AATTATTAACCGTTCACTGATGCCAAGATTAGCCGAAGAATGTATCGGGCGATTAAGCCGCAGCGAACCCATTACTCAAG
TAACAGTTAGTGCAACGAACAACAGTGCTGACTTCGATTTATCTATTAAGTAG

Upstream 100 bases:

>100_bases
TATCTTGCCCCTCAGCATAGTCCTGATAAAAGTGTAAACATTTTGCTTTTATAGTTCGCAATATGGTTCGTGTAGATTAT
AGAAATATAAGGAATAAACA

Downstream 100 bases:

>100_bases
GCCTTAACCAATGAACAGCAAGACCAGCCAAACCTCCACCAATCCGACATCATTTAGCCTGTCACTTAGGGTCAAATTGA
TGTTTGCCATCATGGCGGTT

Product: putative protein disaggregation chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 869

Protein sequence:

>870_residues
MTQVTLTNLVGKLAPALKQALEASAGSAMNQGVGAIEVEHWILQLISQKDPMLMTLCESQKLSIDALVSELTKKISMLPK
GNEGQPTLSHGLTELIKDAWMIASVNYGHGEIVSLHLIQALMQQNVLGVTTLQLESLSNVSLESLQGLIKKTPIARNSSA
PSANGAVDSTPAGNDALSKYTVNLTQQAIDGNIDPISGRNAEVRKAIDILCRKRQNNPIMVGEPGVGKTAVVEGLALRIA
ADEVPSALQGVQIHSLDLGLLQAGASVKGEFENRLKDVINEVKSSEVPIIVFIDEAHTLIGAGGAAGQNDAANLLKPALA
RGEFKTIAATTWAEYKKYFEKDPALTRRFQVVTIEEPNAEDAMQMLRGVAASLQAHHGAFIAESAIEAAVNLSIRYLPSR
QLPDKAISLLDTASARIALTQGAKPEVLETLEQTIRYQENEKSALEKEEALFSNSAELIKELTLSIEENQQTLAAYYTRW
EKEIELVDQIKVIQQEITEAQELNAVDSNKQQQLDGLRIELANVQGEEPLVYAMVDDNTIAQVIANWTGIPVGNMMSDEI
AKLLTLEDELNTRVIGQDVAKNELAKAIRISRAGLTDNRKPIGVFLMCGPSGVGKTETAMALAEQLYGGSNDLTVINMTE
FKEEHKISMLLGSPAGYVGFGEGGVLTEAIRRNPYSVLLLDEMEKAHPGVHDLFYQIFDKGHIKDSEGRTVDFKNTIIIM
TSNAADQAICDVCAQTTDRIDNDKLLESIRPDLQQYFKPAFLGRTTIVPYYPLNDEELAKITEISLNRIKKKLAEQYKAS
FTWDTNFIQFVVDRNTDPTTGGRAVEQIINRSLMPRLAEECIGRLSRSEPITQVTVSATNNSADFDLSIK

Sequences:

>Translated_870_residues
MTQVTLTNLVGKLAPALKQALEASAGSAMNQGVGAIEVEHWILQLISQKDPMLMTLCESQKLSIDALVSELTKKISMLPK
GNEGQPTLSHGLTELIKDAWMIASVNYGHGEIVSLHLIQALMQQNVLGVTTLQLESLSNVSLESLQGLIKKTPIARNSSA
PSANGAVDSTPAGNDALSKYTVNLTQQAIDGNIDPISGRNAEVRKAIDILCRKRQNNPIMVGEPGVGKTAVVEGLALRIA
ADEVPSALQGVQIHSLDLGLLQAGASVKGEFENRLKDVINEVKSSEVPIIVFIDEAHTLIGAGGAAGQNDAANLLKPALA
RGEFKTIAATTWAEYKKYFEKDPALTRRFQVVTIEEPNAEDAMQMLRGVAASLQAHHGAFIAESAIEAAVNLSIRYLPSR
QLPDKAISLLDTASARIALTQGAKPEVLETLEQTIRYQENEKSALEKEEALFSNSAELIKELTLSIEENQQTLAAYYTRW
EKEIELVDQIKVIQQEITEAQELNAVDSNKQQQLDGLRIELANVQGEEPLVYAMVDDNTIAQVIANWTGIPVGNMMSDEI
AKLLTLEDELNTRVIGQDVAKNELAKAIRISRAGLTDNRKPIGVFLMCGPSGVGKTETAMALAEQLYGGSNDLTVINMTE
FKEEHKISMLLGSPAGYVGFGEGGVLTEAIRRNPYSVLLLDEMEKAHPGVHDLFYQIFDKGHIKDSEGRTVDFKNTIIIM
TSNAADQAICDVCAQTTDRIDNDKLLESIRPDLQQYFKPAFLGRTTIVPYYPLNDEELAKITEISLNRIKKKLAEQYKAS
FTWDTNFIQFVVDRNTDPTTGGRAVEQIINRSLMPRLAEECIGRLSRSEPITQVTVSATNNSADFDLSIK
>Mature_869_residues
TQVTLTNLVGKLAPALKQALEASAGSAMNQGVGAIEVEHWILQLISQKDPMLMTLCESQKLSIDALVSELTKKISMLPKG
NEGQPTLSHGLTELIKDAWMIASVNYGHGEIVSLHLIQALMQQNVLGVTTLQLESLSNVSLESLQGLIKKTPIARNSSAP
SANGAVDSTPAGNDALSKYTVNLTQQAIDGNIDPISGRNAEVRKAIDILCRKRQNNPIMVGEPGVGKTAVVEGLALRIAA
DEVPSALQGVQIHSLDLGLLQAGASVKGEFENRLKDVINEVKSSEVPIIVFIDEAHTLIGAGGAAGQNDAANLLKPALAR
GEFKTIAATTWAEYKKYFEKDPALTRRFQVVTIEEPNAEDAMQMLRGVAASLQAHHGAFIAESAIEAAVNLSIRYLPSRQ
LPDKAISLLDTASARIALTQGAKPEVLETLEQTIRYQENEKSALEKEEALFSNSAELIKELTLSIEENQQTLAAYYTRWE
KEIELVDQIKVIQQEITEAQELNAVDSNKQQQLDGLRIELANVQGEEPLVYAMVDDNTIAQVIANWTGIPVGNMMSDEIA
KLLTLEDELNTRVIGQDVAKNELAKAIRISRAGLTDNRKPIGVFLMCGPSGVGKTETAMALAEQLYGGSNDLTVINMTEF
KEEHKISMLLGSPAGYVGFGEGGVLTEAIRRNPYSVLLLDEMEKAHPGVHDLFYQIFDKGHIKDSEGRTVDFKNTIIIMT
SNAADQAICDVCAQTTDRIDNDKLLESIRPDLQQYFKPAFLGRTTIVPYYPLNDEELAKITEISLNRIKKKLAEQYKASF
TWDTNFIQFVVDRNTDPTTGGRAVEQIINRSLMPRLAEECIGRLSRSEPITQVTVSATNNSADFDLSIK

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=32.890365448505, Blast_Score=160, Evalue=4e-39,
Organism=Escherichia coli, GI1788943, Length=683, Percent_Identity=41.8740849194729, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1787109, Length=393, Percent_Identity=38.4223918575064, Blast_Score=250, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6320464, Length=684, Percent_Identity=38.7426900584795, Blast_Score=451, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6323002, Length=822, Percent_Identity=33.4549878345499, Blast_Score=447, Evalue=1e-126,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 94993; Mature: 94862

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVTLTNLVGKLAPALKQALEASAGSAMNQGVGAIEVEHWILQLISQKDPMLMTLCESQ
CCEEEHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEHHHHHHHHHHCCCCCEEEEECCCC
KLSIDALVSELTKKISMLPKGNEGQPTLSHGLTELIKDAWMIASVNYGHGEIVSLHLIQA
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHH
LMQQNVLGVTTLQLESLSNVSLESLQGLIKKTPIARNSSAPSANGAVDSTPAGNDALSKY
HHHCCCCCEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TVNLTQQAIDGNIDPISGRNAEVRKAIDILCRKRQNNPIMVGEPGVGKTAVVEGLALRIA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHEEEE
ADEVPSALQGVQIHSLDLGLLQAGASVKGEFENRLKDVINEVKSSEVPIIVFIDEAHTLI
HHHHHHHHCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
GAGGAAGQNDAANLLKPALARGEFKTIAATTWAEYKKYFEKDPALTRRFQVVTIEEPNAE
ECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCCCHH
DAMQMLRGVAASLQAHHGAFIAESAIEAAVNLSIRYLPSRQLPDKAISLLDTASARIALT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCEEEEE
QGAKPEVLETLEQTIRYQENEKSALEKEEALFSNSAELIKELTLSIEENQQTLAAYYTRW
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHH
EKEIELVDQIKVIQQEITEAQELNAVDSNKQQQLDGLRIELANVQGEEPLVYAMVDDNTI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCCCCCCEEEEEECCCHH
AQVIANWTGIPVGNMMSDEIAKLLTLEDELNTRVIGQDVAKNELAKAIRISRAGLTDNRK
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIGVFLMCGPSGVGKTETAMALAEQLYGGSNDLTVINMTEFKEEHKISMLLGSPAGYVGF
CEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCEEEEECCCCCEEEE
GEGGVLTEAIRRNPYSVLLLDEMEKAHPGVHDLFYQIFDKGHIKDSEGRTVDFKNTIIIM
CCCCHHHHHHHCCCCEEEEEECHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEECCEEEEE
TSNAADQAICDVCAQTTDRIDNDKLLESIRPDLQQYFKPAFLGRTTIVPYYPLNDEELAK
ECCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHCHHHCCCCEEEEEECCCHHHHHH
ITEISLNRIKKKLAEQYKASFTWDTNFIQFVVDRNTDPTTGGRAVEQIINRSLMPRLAEE
HHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
CIGRLSRSEPITQVTVSATNNSADFDLSIK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEC
>Mature Secondary Structure 
TQVTLTNLVGKLAPALKQALEASAGSAMNQGVGAIEVEHWILQLISQKDPMLMTLCESQ
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEHHHHHHHHHHCCCCCEEEEECCCC
KLSIDALVSELTKKISMLPKGNEGQPTLSHGLTELIKDAWMIASVNYGHGEIVSLHLIQA
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHH
LMQQNVLGVTTLQLESLSNVSLESLQGLIKKTPIARNSSAPSANGAVDSTPAGNDALSKY
HHHCCCCCEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TVNLTQQAIDGNIDPISGRNAEVRKAIDILCRKRQNNPIMVGEPGVGKTAVVEGLALRIA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHEEEE
ADEVPSALQGVQIHSLDLGLLQAGASVKGEFENRLKDVINEVKSSEVPIIVFIDEAHTLI
HHHHHHHHCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
GAGGAAGQNDAANLLKPALARGEFKTIAATTWAEYKKYFEKDPALTRRFQVVTIEEPNAE
ECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCCCHH
DAMQMLRGVAASLQAHHGAFIAESAIEAAVNLSIRYLPSRQLPDKAISLLDTASARIALT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCEEEEE
QGAKPEVLETLEQTIRYQENEKSALEKEEALFSNSAELIKELTLSIEENQQTLAAYYTRW
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHH
EKEIELVDQIKVIQQEITEAQELNAVDSNKQQQLDGLRIELANVQGEEPLVYAMVDDNTI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCCCCCCEEEEEECCCHH
AQVIANWTGIPVGNMMSDEIAKLLTLEDELNTRVIGQDVAKNELAKAIRISRAGLTDNRK
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIGVFLMCGPSGVGKTETAMALAEQLYGGSNDLTVINMTEFKEEHKISMLLGSPAGYVGF
CEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCEEEEECCCCCEEEE
GEGGVLTEAIRRNPYSVLLLDEMEKAHPGVHDLFYQIFDKGHIKDSEGRTVDFKNTIIIM
CCCCHHHHHHHCCCCEEEEEECHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEECCEEEEE
TSNAADQAICDVCAQTTDRIDNDKLLESIRPDLQQYFKPAFLGRTTIVPYYPLNDEELAK
ECCCHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHCHHHCCCCEEEEEECCCHHHHHH
ITEISLNRIKKKLAEQYKASFTWDTNFIQFVVDRNTDPTTGGRAVEQIINRSLMPRLAEE
HHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
CIGRLSRSEPITQVTVSATNNSADFDLSIK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]