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The map label for this gene is sglT [H]

Identifier: 218709234

GI number: 218709234

Start: 1333196

End: 1334965

Strand: Reverse

Name: sglT [H]

Synonym: VS_1241

Alternate gene names: 218709234

Gene position: 1334965-1333196 (Counterclockwise)

Preceding gene: 218709235

Following gene: 218709230

Centisome position: 40.46

GC content: 45.59

Gene sequence:

>1770_bases
ATGACTATTGATACTTTTGTTGTTCTCGCCTACTTCTTCTTTTTAATCGCGATTGGTTGGATGTTCCGTAAGTTCACCAC
CTCTACAAGTGATTACTTCAGAGGGGGCGGCAAAATGTTGTGGTGGATGGTTGGTGCAACCGCCTTCATGACACAGTTTT
CAGCATGGACGTTTACAGGTGCCGCAGGACGCGCGTTCAATGACGGTTTCGTTATTGTAATCCTATTCCTAGCCAATGCT
TTTGGCTACTTCATGAACTATATGTACTTCGCTCCAAAGTTCCGCCAACTTCGTGTAGTAACGGCGATCGAAGCCATTCG
TCAACGCTTTGGTAAAACGTCTGAACAGTTCTTCACATGGGCAGGTATGCCTGACAGTCTTATCTCTGCAGGTATCTGGC
TAAACGGTCTCGCTATCTTCGTAGCTGCTGTATTCAACATCCCAATGGAAGCAACCATTGTGGTAACGGGTATGGTTCTA
GTATTGATGGCAGTAACAGGCGGCTCTTGGGCGGTTGTTGCTTCTGACTTCATGCAAATGCTTGTAATCATGGCCGTGAC
AATCACTTGTGCGGTTGCGGCTTACTTCCACGGTGGTGGCTTAACTAACATCGTTGCTAACTTCGACGGCGACTTCATGT
TAGGTAACAACCTAAACTACATGAGCATCTTCATCCTTTGGGTTGTGTTCATCTTCGTGAAGCAATTCGGTGTAATGAAC
AACAGCATCAACGCTTACCGTTACCTATGTGCAAAAGACAGTGAAAACGCACGTAAAGCGGCAGGCCTAGCATGTATCCT
TATGGTTGTTGGTCCACTAATTTGGTTCCTACCACCATGGTACGTAAGTGCATTCATGCCTGAGTTCGCATTAGAGTACG
CTTCAATGGGTGATAAAGCGGGTGATGCTGCTTACCTAGCATTCGTACAGAACGTAATGCCAGCAGGTATGGTTGGTCTT
CTTATGTCAGCAATGTTCGCTGCAACGATGTCTTCTATGGATTCAGGTTTGAACCGTAACGCTGGCATCTTTGTAATGAA
CTTCTACAGCCCGATTCTTCGTCAAAATGCGACTCAGAAAGAGCTGGTTATTGTAAGTAAGCTAACGACTATTATGATGG
GTGTTATCATCATCGCGATTGGCTTGTTCATTAACTCTCTACGTCACTTGAGCTTGTTCGATATCGTAATGAACGTAGGT
GCGTTAATTGGCTTCCCAATGCTTATCCCTGTACTACTTGGTATGTGGATTCGTAAGACGCCTGACTGGGCTGGTTGGTC
TACTCTCGTGGTTGGTGGTTTCGTTTCTTACATCTTCGGTATCTCGCTTCAAGCAGAAGACATCGAGCACCTATTCGGTA
TGGAAACAGCGCTTACTGGCCGTGAATGGAGCGACTTGAAAGTAGGTCTTAGCTTAGCTGCTCACGTAGTGTTTACTGGT
GGTTACTTCATGCTAACTTCTCGCTTCTACAAAGGCCTATCGCCTGAACGTGAGAAAGAAGTTGACCAACTATTCACTAA
CTGGAACACACCATTAGTAGCGGAAGGTGAAGAGCAACAAAACCTAGATACTAAACAGCGTTCAATGCTCGGTAAGCTTA
TCAGCACAGCAGGTTTCGGTATCCTAGCAATGGCTCTGATTCCAAACGAACCAACAGGACGCTTGTTGTTCCTACTATGT
GGTTCGATGGTACTAACCGTTGGTATCCTACTGGTTAATGCGGCCAAAAACCCTGCAAAAAAGCTAAATGATGGAGCGAT
TCTCAAATAG

Upstream 100 bases:

>100_bases
TGCGCCCCAGATCACGATAAAGACATATTGTAGTACAAATAAACATGCAGAAGGAGTAATCTAGGTGTCAGTTAATTATG
AAACTTAAAAGGCTGAAAAG

Downstream 100 bases:

>100_bases
TATAGAGAAAGAACACTATTCGCTTAGCTGATATAACACATAAAATAATGCCCATGCTTCCCCCCGACAGCATGGGCTTT
TTGTTGTTTTATCGAGGCTA

Product: putative sodium/substrate symport

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MTIDTFVVLAYFFFLIAIGWMFRKFTTSTSDYFRGGGKMLWWMVGATAFMTQFSAWTFTGAAGRAFNDGFVIVILFLANA
FGYFMNYMYFAPKFRQLRVVTAIEAIRQRFGKTSEQFFTWAGMPDSLISAGIWLNGLAIFVAAVFNIPMEATIVVTGMVL
VLMAVTGGSWAVVASDFMQMLVIMAVTITCAVAAYFHGGGLTNIVANFDGDFMLGNNLNYMSIFILWVVFIFVKQFGVMN
NSINAYRYLCAKDSENARKAAGLACILMVVGPLIWFLPPWYVSAFMPEFALEYASMGDKAGDAAYLAFVQNVMPAGMVGL
LMSAMFAATMSSMDSGLNRNAGIFVMNFYSPILRQNATQKELVIVSKLTTIMMGVIIIAIGLFINSLRHLSLFDIVMNVG
ALIGFPMLIPVLLGMWIRKTPDWAGWSTLVVGGFVSYIFGISLQAEDIEHLFGMETALTGREWSDLKVGLSLAAHVVFTG
GYFMLTSRFYKGLSPEREKEVDQLFTNWNTPLVAEGEEQQNLDTKQRSMLGKLISTAGFGILAMALIPNEPTGRLLFLLC
GSMVLTVGILLVNAAKNPAKKLNDGAILK

Sequences:

>Translated_589_residues
MTIDTFVVLAYFFFLIAIGWMFRKFTTSTSDYFRGGGKMLWWMVGATAFMTQFSAWTFTGAAGRAFNDGFVIVILFLANA
FGYFMNYMYFAPKFRQLRVVTAIEAIRQRFGKTSEQFFTWAGMPDSLISAGIWLNGLAIFVAAVFNIPMEATIVVTGMVL
VLMAVTGGSWAVVASDFMQMLVIMAVTITCAVAAYFHGGGLTNIVANFDGDFMLGNNLNYMSIFILWVVFIFVKQFGVMN
NSINAYRYLCAKDSENARKAAGLACILMVVGPLIWFLPPWYVSAFMPEFALEYASMGDKAGDAAYLAFVQNVMPAGMVGL
LMSAMFAATMSSMDSGLNRNAGIFVMNFYSPILRQNATQKELVIVSKLTTIMMGVIIIAIGLFINSLRHLSLFDIVMNVG
ALIGFPMLIPVLLGMWIRKTPDWAGWSTLVVGGFVSYIFGISLQAEDIEHLFGMETALTGREWSDLKVGLSLAAHVVFTG
GYFMLTSRFYKGLSPEREKEVDQLFTNWNTPLVAEGEEQQNLDTKQRSMLGKLISTAGFGILAMALIPNEPTGRLLFLLC
GSMVLTVGILLVNAAKNPAKKLNDGAILK
>Mature_588_residues
TIDTFVVLAYFFFLIAIGWMFRKFTTSTSDYFRGGGKMLWWMVGATAFMTQFSAWTFTGAAGRAFNDGFVIVILFLANAF
GYFMNYMYFAPKFRQLRVVTAIEAIRQRFGKTSEQFFTWAGMPDSLISAGIWLNGLAIFVAAVFNIPMEATIVVTGMVLV
LMAVTGGSWAVVASDFMQMLVIMAVTITCAVAAYFHGGGLTNIVANFDGDFMLGNNLNYMSIFILWVVFIFVKQFGVMNN
SINAYRYLCAKDSENARKAAGLACILMVVGPLIWFLPPWYVSAFMPEFALEYASMGDKAGDAAYLAFVQNVMPAGMVGLL
MSAMFAATMSSMDSGLNRNAGIFVMNFYSPILRQNATQKELVIVSKLTTIMMGVIIIAIGLFINSLRHLSLFDIVMNVGA
LIGFPMLIPVLLGMWIRKTPDWAGWSTLVVGGFVSYIFGISLQAEDIEHLFGMETALTGREWSDLKVGLSLAAHVVFTGG
YFMLTSRFYKGLSPEREKEVDQLFTNWNTPLVAEGEEQQNLDTKQRSMLGKLISTAGFGILAMALIPNEPTGRLLFLLCG
SMVLTVGILLVNAAKNPAKKLNDGAILK

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI17941285, Length=468, Percent_Identity=24.5726495726496, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4507031, Length=465, Percent_Identity=24.7311827956989, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI14140236, Length=472, Percent_Identity=22.8813559322034, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4507033, Length=469, Percent_Identity=23.454157782516, Blast_Score=90, Evalue=6e-18,
Organism=Escherichia coli, GI1790113, Length=444, Percent_Identity=22.7477477477477, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539284, Length=428, Percent_Identity=23.8317757009346, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221459586, Length=433, Percent_Identity=22.8637413394919, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221459584, Length=365, Percent_Identity=23.2876712328767, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24651739, Length=447, Percent_Identity=21.923937360179, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221459588, Length=405, Percent_Identity=22.962962962963, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 64884; Mature: 64752

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
TIDTFVVLAYFFFLIAIGWMFRKFTTSTSDYFRGGGKMLWWMVGATAFMTQFSAWTFTG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHEEEC
AAGRAFNDGFVIVILFLANAFGYFMNYMYFAPKFRQLRVVTAIEAIRQRFGKTSEQFFTW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHEEE
AGMPDSLISAGIWLNGLAIFVAAVFNIPMEATIVVTGMVLVLMAVTGGSWAVVASDFMQM
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LVIMAVTITCAVAAYFHGGGLTNIVANFDGDFMLGNNLNYMSIFILWVVFIFVKQFGVMN
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCC
NSINAYRYLCAKDSENARKAAGLACILMVVGPLIWFLPPWYVSAFMPEFALEYASMGDKA
CCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
GDAAYLAFVQNVMPAGMVGLLMSAMFAATMSSMDSGLNRNAGIFVMNFYSPILRQNATQK
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCCCHH
ELVIVSKLTTIMMGVIIIAIGLFINSLRHLSLFDIVMNVGALIGFPMLIPVLLGMWIRKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDWAGWSTLVVGGFVSYIFGISLQAEDIEHLFGMETALTGREWSDLKVGLSLAAHVVFTG
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHCC
GYFMLTSRFYKGLSPEREKEVDQLFTNWNTPLVAEGEEQQNLDTKQRSMLGKLISTAGFG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHCCHH
ILAMALIPNEPTGRLLFLLCGSMVLTVGILLVNAAKNPAKKLNDGAILK
HHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]