Click here to switch to the map view.

The map label for this gene is citT [C]

Identifier: 218709192

GI number: 218709192

Start: 1271538

End: 1272908

Strand: Reverse

Name: citT [C]

Synonym: VS_1199

Alternate gene names: 218709192

Gene position: 1272908-1271538 (Counterclockwise)

Preceding gene: 218709194

Following gene: 218709189

Centisome position: 38.58

GC content: 45.51

Gene sequence:

>1371_bases
ATGACGGCACTTGTTACTACACTGAAACACTGGTTGTTTACCCGCAACAGCATGATATTAATTGGTAATTTCACGCTATT
TGCAGTTTTGCTCAATTCCCTGCCATTCGAAGCGCAAGTGAATACGGGTTTAAGTATTCTCGTGTTCGTTGCTATTCTAT
GGTTAACAGAAGCTATCCACGTCAGCATCACCGCTTTGCTCGTTCCCCTATTGGCTGTCTTGTTTGGTGTATTCAACACG
CCCGCAGCACTGGCTAACTTTTCGAATCCCATCATCTTCTTATTCATGGGCGGATTCGCGTTGGCAGCCGCACTGAACAA
GCAAGAGCTGGATAAAGCGATAGCTGACAAAGTATTGCTGATAGCAAAAGGCAGAATGTCGGTCGCCGTGTTCATGTTGT
TCGGTGTGAGTGCGGGTTTATCCATGTGGATCTCAAACACCGCCACCACAGCAATGATGCTCCCTCTAGTTCTTGGTATC
ATGAACAAAGTCGACCAAAGTGAAGACCGAAACACCTACGTGTTCGTGCTATTGGGTATCGCTTACTGTGCTTCAATCGG
TGGTATCGCAACTTTAGTTGGTAGCCCACCAAACGCCATTGCTGCGGCAGAAGTTGGCTTGAGCTTCACAGAGTGGATGG
CGCTTGGACTACCTATCTCGATGATCTTATTGCCAATCACGATGATTATTTTGTACGTGATGACTAAGCCAAAACTTGAC
CACAAATTCGAGCTAGACCATGCACCTGTCGAGTGGACAAACAGCAAGAAAATCACACTGTCTATCTTCCTTTTAACGGT
AACGCTTTGGATATTCGGCAAACCAATCAACGCAATGATTGGCGGATTCTCTAAGTTTGATAGTTTGGTAGCAATTGGTG
CAATTGTACTGCTTGGCGCTTCTAGAGCCGTGGAATGGAAAGACGTTGAGAAGACAACGGATTGGGGTGTACTTATCCTG
TTCGGTGGTGGTATCTGTTTAAGTAACATTCTAAAAGCGACAGGAACAAGCGTATTCTTAGCACACTCACTAAGCGGATT
TTTAGAAACAGCAGGCGTACTTCTTACAATTCTAGCTGTGGTAGCCTTCGTGGTATTCCTAACGGAATTTGCAAGTAACA
CAGCGAGTGCGGCATTGCTTGTCCCTGTATTTGCAACCATTGCTGAAGCGCTGGGTATGTCACCTGTTATCTTATCTGCA
CTGATTGCGATTGCCGCATCTTGTGCCTTCATGCTACCAGTCGCGACACCACCTAATGCGATTGTATTTGGCTCTGGTCA
TATCAAACAAAAAGAAATGATGCGAGTCGGTATGGTGTTGAACCTAGTTTGTATCCTAGTTCTGACTCTGTTCGCTTGGA
TTTTCTGGTAA

Upstream 100 bases:

>100_bases
AAGTCTGACCCTACATCAAGTCTATATACCTCGAAAATAATAAGCACCGCTCAACGAAGTCGTGCACCAATAAAACGAGG
ATAAACAAAAGGAGCGTCTT

Downstream 100 bases:

>100_bases
ACACTAACGCTTATAGAGAAAGCTTTACAGGCAAGTGCTTAGAAACACATATTTATAGGTAAATACTTATAGATAAATGT
TTACAGGAATGCCCCCTCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTALVTTLKHWLFTRNSMILIGNFTLFAVLLNSLPFEAQVNTGLSILVFVAILWLTEAIHVSITALLVPLLAVLFGVFNT
PAALANFSNPIIFLFMGGFALAAALNKQELDKAIADKVLLIAKGRMSVAVFMLFGVSAGLSMWISNTATTAMMLPLVLGI
MNKVDQSEDRNTYVFVLLGIAYCASIGGIATLVGSPPNAIAAAEVGLSFTEWMALGLPISMILLPITMIILYVMTKPKLD
HKFELDHAPVEWTNSKKITLSIFLLTVTLWIFGKPINAMIGGFSKFDSLVAIGAIVLLGASRAVEWKDVEKTTDWGVLIL
FGGGICLSNILKATGTSVFLAHSLSGFLETAGVLLTILAVVAFVVFLTEFASNTASAALLVPVFATIAEALGMSPVILSA
LIAIAASCAFMLPVATPPNAIVFGSGHIKQKEMMRVGMVLNLVCILVLTLFAWIFW

Sequences:

>Translated_456_residues
MTALVTTLKHWLFTRNSMILIGNFTLFAVLLNSLPFEAQVNTGLSILVFVAILWLTEAIHVSITALLVPLLAVLFGVFNT
PAALANFSNPIIFLFMGGFALAAALNKQELDKAIADKVLLIAKGRMSVAVFMLFGVSAGLSMWISNTATTAMMLPLVLGI
MNKVDQSEDRNTYVFVLLGIAYCASIGGIATLVGSPPNAIAAAEVGLSFTEWMALGLPISMILLPITMIILYVMTKPKLD
HKFELDHAPVEWTNSKKITLSIFLLTVTLWIFGKPINAMIGGFSKFDSLVAIGAIVLLGASRAVEWKDVEKTTDWGVLIL
FGGGICLSNILKATGTSVFLAHSLSGFLETAGVLLTILAVVAFVVFLTEFASNTASAALLVPVFATIAEALGMSPVILSA
LIAIAASCAFMLPVATPPNAIVFGSGHIKQKEMMRVGMVLNLVCILVLTLFAWIFW
>Mature_455_residues
TALVTTLKHWLFTRNSMILIGNFTLFAVLLNSLPFEAQVNTGLSILVFVAILWLTEAIHVSITALLVPLLAVLFGVFNTP
AALANFSNPIIFLFMGGFALAAALNKQELDKAIADKVLLIAKGRMSVAVFMLFGVSAGLSMWISNTATTAMMLPLVLGIM
NKVDQSEDRNTYVFVLLGIAYCASIGGIATLVGSPPNAIAAAEVGLSFTEWMALGLPISMILLPITMIILYVMTKPKLDH
KFELDHAPVEWTNSKKITLSIFLLTVTLWIFGKPINAMIGGFSKFDSLVAIGAIVLLGASRAVEWKDVEKTTDWGVLILF
GGGICLSNILKATGTSVFLAHSLSGFLETAGVLLTILAVVAFVVFLTEFASNTASAALLVPVFATIAEALGMSPVILSAL
IAIAASCAFMLPVATPPNAIVFGSGHIKQKEMMRVGMVLNLVCILVLTLFAWIFW

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=503, Percent_Identity=27.4353876739563, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI31795546, Length=354, Percent_Identity=25.1412429378531, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI31377715, Length=145, Percent_Identity=39.3103448275862, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI58761541, Length=145, Percent_Identity=39.3103448275862, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI301069353, Length=145, Percent_Identity=39.3103448275862, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI301069349, Length=145, Percent_Identity=39.3103448275862, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI301069346, Length=145, Percent_Identity=39.3103448275862, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI19923838, Length=348, Percent_Identity=28.1609195402299, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI219802232, Length=442, Percent_Identity=25.3393665158371, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4506979, Length=147, Percent_Identity=34.6938775510204, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI225637552, Length=147, Percent_Identity=34.6938775510204, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI225637549, Length=147, Percent_Identity=34.6938775510204, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786829, Length=409, Percent_Identity=26.4058679706601, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786986, Length=407, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789444, Length=415, Percent_Identity=26.7469879518072, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71988385, Length=491, Percent_Identity=27.9022403258656, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71989118, Length=544, Percent_Identity=26.1029411764706, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32565804, Length=452, Percent_Identity=28.5398230088496, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17551790, Length=561, Percent_Identity=24.777183600713, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32564681, Length=497, Percent_Identity=22.9376257545272, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6322263, Length=408, Percent_Identity=27.4509803921569, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324340, Length=396, Percent_Identity=25.7575757575758, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319885, Length=435, Percent_Identity=27.1264367816092, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281362116, Length=529, Percent_Identity=26.6540642722117, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281362114, Length=529, Percent_Identity=26.4650283553875, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281362112, Length=529, Percent_Identity=26.4650283553875, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281366409, Length=480, Percent_Identity=25.2083333333333, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17737623, Length=480, Percent_Identity=25.2083333333333, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24666468, Length=480, Percent_Identity=25.2083333333333, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45551633, Length=480, Percent_Identity=25.2083333333333, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI78706796, Length=483, Percent_Identity=24.6376811594203, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706798, Length=483, Percent_Identity=24.6376811594203, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 48746; Mature: 48615

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALVTTLKHWLFTRNSMILIGNFTLFAVLLNSLPFEAQVNTGLSILVFVAILWLTEAIH
CHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
VSITALLVPLLAVLFGVFNTPAALANFSNPIIFLFMGGFALAAALNKQELDKAIADKVLL
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHEEE
IAKGRMSVAVFMLFGVSAGLSMWISNTATTAMMLPLVLGIMNKVDQSEDRNTYVFVLLGI
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHH
AYCASIGGIATLVGSPPNAIAAAEVGLSFTEWMALGLPISMILLPITMIILYVMTKPKLD
HHHHHHCCHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
HKFELDHAPVEWTNSKKITLSIFLLTVTLWIFGKPINAMIGGFSKFDSLVAIGAIVLLGA
CEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCC
SRAVEWKDVEKTTDWGVLILFGGGICLSNILKATGTSVFLAHSLSGFLETAGVLLTILAV
CCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAFVVFLTEFASNTASAALLVPVFATIAEALGMSPVILSALIAIAASCAFMLPVATPPNA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCE
IVFGSGHIKQKEMMRVGMVLNLVCILVLTLFAWIFW
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TALVTTLKHWLFTRNSMILIGNFTLFAVLLNSLPFEAQVNTGLSILVFVAILWLTEAIH
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHH
VSITALLVPLLAVLFGVFNTPAALANFSNPIIFLFMGGFALAAALNKQELDKAIADKVLL
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHEEE
IAKGRMSVAVFMLFGVSAGLSMWISNTATTAMMLPLVLGIMNKVDQSEDRNTYVFVLLGI
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHH
AYCASIGGIATLVGSPPNAIAAAEVGLSFTEWMALGLPISMILLPITMIILYVMTKPKLD
HHHHHHCCHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
HKFELDHAPVEWTNSKKITLSIFLLTVTLWIFGKPINAMIGGFSKFDSLVAIGAIVLLGA
CEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCC
SRAVEWKDVEKTTDWGVLILFGGGICLSNILKATGTSVFLAHSLSGFLETAGVLLTILAV
CCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAFVVFLTEFASNTASAALLVPVFATIAEALGMSPVILSALIAIAASCAFMLPVATPPNA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCE
IVFGSGHIKQKEMMRVGMVLNLVCILVLTLFAWIFW
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]