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The map label for this gene is trxB [H]

Identifier: 218709179

GI number: 218709179

Start: 1255559

End: 1256518

Strand: Reverse

Name: trxB [H]

Synonym: VS_1186

Alternate gene names: 218709179

Gene position: 1256518-1255559 (Counterclockwise)

Preceding gene: 218709183

Following gene: 218709178

Centisome position: 38.08

GC content: 47.08

Gene sequence:

>960_bases
ATGAGCGACGTAAAGCACTGTAATTTATTGATTCTTGGTTCTGGCCCTGCTGGCTATACAGCTGCAGTTTACGCTGCTCG
TGCAAACCTAAACCCTGTACTTGTTACGGGTATGCAGCAAGGTGGTCAGCTTACAACCACAACAGAAGTAGAAAACTGGC
CGGGTGATCCTGAAGGTTTAACGGGTCCAGCTCTAATGGATCGCATGAAAGAGCACGCAGAGCGCTTTGAAACAGAGATC
TTGTTCGACCACATTAACGAAGTCGATCTATCAAACCGACCTTTCCGTCTTAAAGGCGATTCTGGCGAGTACACGTGTGA
TGCATTGATCATCTCAACGGGTGCATCAGCTAAGTACTTAGGTTTAGATTCTGAAGAAGCATTCAAAGGCCGCGGCGTTT
CTGCTTGTGCTACATGTGATGGTTTCTTCTACCGCAACCAGAAAGTAGCGGTTGTGGGTGGTGGTAACACCGCTGTTGAA
GAAGCACTTTACCTATCTAATATCGCGTCTGAAGTTCACCTAGTTCACCGTCGTGACACGTTCCGTGCTGAAAAGATTCT
AGTGAAACGTTTAATGGACAAAGTAGAGAACGGCAACATTGTTCTTCACACTGATCGCACGCTAGACGAAGTTCTAGGCG
ACGACATGGGCGTAACGGGCGTTCGTATTAAAGATACTCAGTCTGATAAGACAGAAGACATCGAAGTAATGGGCGCATTC
ATTGCTATCGGTCACCAACCAAACACTGAAATCTTCAAAGGCCAAGTCGACATGAAAGATGACTACATAATCGTTCAGTC
TGGTCTTGAAGGTAACGCAACGCAAACCAGCATCCCAGGCGTGTTCGCTGCTGGTGATGTAATGGACCACAACTACCGCC
AAGCAATCACTTCTGCTGGTACAGGTTGTATGGCTGCACTGGATGCTGAACGCTTCCTAGATGGCCTTAACGATAAGTAA

Upstream 100 bases:

>100_bases
TAATTACACTTCTGCCCTTGTTTACACTTTTATTGCCTCCATATTTTCCATACAATCCTAAGCGATTATAAATAAAAACA
ATTTCAATTTCGGAGTCCTC

Downstream 100 bases:

>100_bases
ATCTGAGATTGCAGATTTAAATATCGAAGCCCTCACCTCAGTAGATGCAGGGCGTCATCACATTTTGTTGTAAATCCCTA
GAGCCCAGTGGTATATCCAC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSDVKHCNLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTTEVENWPGDPEGLTGPALMDRMKEHAERFETEI
LFDHINEVDLSNRPFRLKGDSGEYTCDALIISTGASAKYLGLDSEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIASEVHLVHRRDTFRAEKILVKRLMDKVENGNIVLHTDRTLDEVLGDDMGVTGVRIKDTQSDKTEDIEVMGAF
IAIGHQPNTEIFKGQVDMKDDYIIVQSGLEGNATQTSIPGVFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDGLNDK

Sequences:

>Translated_319_residues
MSDVKHCNLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTTEVENWPGDPEGLTGPALMDRMKEHAERFETEI
LFDHINEVDLSNRPFRLKGDSGEYTCDALIISTGASAKYLGLDSEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIASEVHLVHRRDTFRAEKILVKRLMDKVENGNIVLHTDRTLDEVLGDDMGVTGVRIKDTQSDKTEDIEVMGAF
IAIGHQPNTEIFKGQVDMKDDYIIVQSGLEGNATQTSIPGVFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDGLNDK
>Mature_318_residues
SDVKHCNLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTTEVENWPGDPEGLTGPALMDRMKEHAERFETEIL
FDHINEVDLSNRPFRLKGDSGEYTCDALIISTGASAKYLGLDSEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLSNIASEVHLVHRRDTFRAEKILVKRLMDKVENGNIVLHTDRTLDEVLGDDMGVTGVRIKDTQSDKTEDIEVMGAFI
AIGHQPNTEIFKGQVDMKDDYIIVQSGLEGNATQTSIPGVFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDGLNDK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=81.5047021943574, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=31.7307692307692, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321898, Length=327, Percent_Identity=47.0948012232416, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=48.297213622291, Blast_Score=288, Evalue=1e-78,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34527; Mature: 34396

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVKHCNLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTTEVENWPGDPEGL
CCCCCEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMDRMKEHAERFETEILFDHINEVDLSNRPFRLKGDSGEYTCDALIISTGASAKYL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLDSEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLVHRRDT
CCCCHHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCH
FRAEKILVKRLMDKVENGNIVLHTDRTLDEVLGDDMGVTGVRIKDTQSDKTEDIEVMGAF
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCCHHHEEEEE
IAIGHQPNTEIFKGQVDMKDDYIIVQSGLEGNATQTSIPGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCEEECEECCCCCEEEEECCCCCCCCCCCCCCEEEECCHHCCHHHHHHHHCC
TGCMAALDAERFLDGLNDK
CCHHHHHCHHHHHHCCCCC
>Mature Secondary Structure 
SDVKHCNLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTTEVENWPGDPEGL
CCCCEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMDRMKEHAERFETEILFDHINEVDLSNRPFRLKGDSGEYTCDALIISTGASAKYL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLDSEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLVHRRDT
CCCCHHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCH
FRAEKILVKRLMDKVENGNIVLHTDRTLDEVLGDDMGVTGVRIKDTQSDKTEDIEVMGAF
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCCHHHEEEEE
IAIGHQPNTEIFKGQVDMKDDYIIVQSGLEGNATQTSIPGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCEEECEECCCCCEEEEECCCCCCCCCCCCCCEEEECCHHCCHHHHHHHHCC
TGCMAALDAERFLDGLNDK
CCHHHHHCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]