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The map label for this gene is hlyB [H]

Identifier: 218709091

GI number: 218709091

Start: 1158216

End: 1160108

Strand: Reverse

Name: hlyB [H]

Synonym: VS_1097

Alternate gene names: 218709091

Gene position: 1160108-1158216 (Counterclockwise)

Preceding gene: 218709092

Following gene: 218709086

Centisome position: 35.16

GC content: 41.84

Gene sequence:

>1893_bases
ATGACCGTCAAAAATAAGATTATGCTAACAATTAGCGGCCTAATCTGTTTAACGATTTTAGTTATATCTACGATAGGATA
TTTCGAATTTAAGTCTGCCACCACGGATGACTACCGTCATAACTTGTCTACGAAATCGTTTCTTGTAGCCAAAGCTGTCG
AAGGGAAAATGGAAGCGTATTTCGGCGCTTTGGAAAGCATTTCAACCAGTATCCATACTGATAGATCCGGTAACATCATG
ATCAACCCGATGCTGTTGAAAATGATGACGAACAGTAAAGAATCTCTTGGTGTTCTTAATATTTACATCGGTCTTCCTGA
TGGCAAAACTTACGACGTTAAAAATCAAGGTATCATTCCCAACTTTAATGCTAAACAAAAACAGCGTGAGTGGTTCAATC
TCGGATTTTCTGGCGCAAAGCGCTCAGTAACCAACCCTTACCTAGCAACAACAGGGCATTTAACCATGTCGGTTGTTATC
CCTTTCAAAGCCAGAGGTGAAACGAAAGCTGTTATTGGCCTTAGTCTTAAAATGAGTGACATCACAGACTACATAAACGA
GTTATCTGATGTTCCAAATTTATTTGTCTCTCGCCAAGATGGTTTCCTTGTTGCCGCTAGCTATGAAGACTTTATTGGTA
AAAATATCTACGATCTTCGACCATCATATCGTGAACACGGTAGTAAGATGACCAGTGAGCACTCTTACAATGTTCCAGAT
AAAGGCGACTTTTATGTCGTTTCGTCTCAAATTGAGTCATTAGGTTGGAATATTTGGGCTTGGGCAAGTTGGGACGACAT
TGAAGCGCCTTCAAATGCGATGGTGAAAATAAATACTGTAGTTGGTCTAATTTTCGCGATTATGGCAACCGGAATAACAT
TCTTATTAGTCACCCGATTAATGTATCGTCCTATTGGCGGAGAGCCGCAATACATCGAAGCTCTTGTTAGTCGAATTTCG
GCAGGAGACCTGACCAACATCCCTAAATTAAATGGTGATGAAACGGGGATCTACCGTTCAACTCTTGAAATGGCAGGTAA
CCTCCAAGGTATTATTGGCAATATTGAGCAGTCTTCAAACTCTCTCTCATCACAATCTTCATCTCTTGAGACCTCGTCAA
ATCAGTTAAGTACCTCATCAGAAGAGCAAATGATGCAGCTAGAGCAAGTTGCAACCGCGATGAATCAGATGACCGCGACT
GTTGCGGAAGTGGCTCAAAATGCGATGCAGGCATCATCATCATCCAATGAGGCAAGCCTTTCATCTCAGTCAGGTCTTGA
GACTGTGGGTGACATGAACCAGCAAATCAGCTTACTTGTAACGAATATTGAGCAGGTTCAAGATTCGATTCTTGGTGTTG
AAAAAGAAACTCAAAATGTAGGTAGCATACTTGATGTTATCCGAGGTATTGCTGAGCAAACAAACTTGCTGGCATTAAAC
GCAGCAATTGAAGCAGCTCGAGCGGGTGAGCAAGGTCGCGGCTTCGCCGTCGTGGCTGACGAGGTGCGTAACCTCGCTAA
CAAGACACAAGAAAGCACGAACGAAATACAAACCATGATTTCATCACTTCAAACTCAAGCAAAACAATCTGTTGAGCTTA
TGGTTGAAAATGCGGAAACAGCTAAAGTAACTCGTGAAAAGTCAGATCAAGCGAGTCAAATGCTGAATACTATTCAGCAT
GAGATTGGGACAATTCAAGACATGAACAACCAGATTGCAGCGGCAGCGGAAGAACAATCGCAAGTAGCCGTTGAAATCAA
CGAAAATGTAGTGAATGTAAATGATTTGGCGCGAGCGACTGTCGATGACGTCCAGCAAAATGTTCAAACAGCGCAAAATG
TTAATAATGTTTCGGACGAACTGCATCAAACGATAAAGATGTTTAAGATCTAA

Upstream 100 bases:

>100_bases
TTTCCCTTACAAAACGACCAACAAATAAATTGTAACCCTATGTTAGCATACGGATAATTTAGTCAATAAAATAAGCAACA
ACTGTTAAGGAAATGCTCTG

Downstream 100 bases:

>100_bases
TCTTAGATAAGCTAAACGTACCGACAACCTATACGTTAAAGCCTAAGTATCAAAATCTTCGGCTTAAAAAAAGATAACGT
AATTAAAACCGCCTTCTCTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MTVKNKIMLTISGLICLTILVISTIGYFEFKSATTDDYRHNLSTKSFLVAKAVEGKMEAYFGALESISTSIHTDRSGNIM
INPMLLKMMTNSKESLGVLNIYIGLPDGKTYDVKNQGIIPNFNAKQKQREWFNLGFSGAKRSVTNPYLATTGHLTMSVVI
PFKARGETKAVIGLSLKMSDITDYINELSDVPNLFVSRQDGFLVAASYEDFIGKNIYDLRPSYREHGSKMTSEHSYNVPD
KGDFYVVSSQIESLGWNIWAWASWDDIEAPSNAMVKINTVVGLIFAIMATGITFLLVTRLMYRPIGGEPQYIEALVSRIS
AGDLTNIPKLNGDETGIYRSTLEMAGNLQGIIGNIEQSSNSLSSQSSSLETSSNQLSTSSEEQMMQLEQVATAMNQMTAT
VAEVAQNAMQASSSSNEASLSSQSGLETVGDMNQQISLLVTNIEQVQDSILGVEKETQNVGSILDVIRGIAEQTNLLALN
AAIEAARAGEQGRGFAVVADEVRNLANKTQESTNEIQTMISSLQTQAKQSVELMVENAETAKVTREKSDQASQMLNTIQH
EIGTIQDMNNQIAAAAEEQSQVAVEINENVVNVNDLARATVDDVQQNVQTAQNVNNVSDELHQTIKMFKI

Sequences:

>Translated_630_residues
MTVKNKIMLTISGLICLTILVISTIGYFEFKSATTDDYRHNLSTKSFLVAKAVEGKMEAYFGALESISTSIHTDRSGNIM
INPMLLKMMTNSKESLGVLNIYIGLPDGKTYDVKNQGIIPNFNAKQKQREWFNLGFSGAKRSVTNPYLATTGHLTMSVVI
PFKARGETKAVIGLSLKMSDITDYINELSDVPNLFVSRQDGFLVAASYEDFIGKNIYDLRPSYREHGSKMTSEHSYNVPD
KGDFYVVSSQIESLGWNIWAWASWDDIEAPSNAMVKINTVVGLIFAIMATGITFLLVTRLMYRPIGGEPQYIEALVSRIS
AGDLTNIPKLNGDETGIYRSTLEMAGNLQGIIGNIEQSSNSLSSQSSSLETSSNQLSTSSEEQMMQLEQVATAMNQMTAT
VAEVAQNAMQASSSSNEASLSSQSGLETVGDMNQQISLLVTNIEQVQDSILGVEKETQNVGSILDVIRGIAEQTNLLALN
AAIEAARAGEQGRGFAVVADEVRNLANKTQESTNEIQTMISSLQTQAKQSVELMVENAETAKVTREKSDQASQMLNTIQH
EIGTIQDMNNQIAAAAEEQSQVAVEINENVVNVNDLARATVDDVQQNVQTAQNVNNVSDELHQTIKMFKI
>Mature_629_residues
TVKNKIMLTISGLICLTILVISTIGYFEFKSATTDDYRHNLSTKSFLVAKAVEGKMEAYFGALESISTSIHTDRSGNIMI
NPMLLKMMTNSKESLGVLNIYIGLPDGKTYDVKNQGIIPNFNAKQKQREWFNLGFSGAKRSVTNPYLATTGHLTMSVVIP
FKARGETKAVIGLSLKMSDITDYINELSDVPNLFVSRQDGFLVAASYEDFIGKNIYDLRPSYREHGSKMTSEHSYNVPDK
GDFYVVSSQIESLGWNIWAWASWDDIEAPSNAMVKINTVVGLIFAIMATGITFLLVTRLMYRPIGGEPQYIEALVSRISA
GDLTNIPKLNGDETGIYRSTLEMAGNLQGIIGNIEQSSNSLSSQSSSLETSSNQLSTSSEEQMMQLEQVATAMNQMTATV
AEVAQNAMQASSSSNEASLSSQSGLETVGDMNQQISLLVTNIEQVQDSILGVEKETQNVGSILDVIRGIAEQTNLLALNA
AIEAARAGEQGRGFAVVADEVRNLANKTQESTNEIQTMISSLQTQAKQSVELMVENAETAKVTREKSDQASQMLNTIQHE
IGTIQDMNNQIAAAAEEQSQVAVEINENVVNVNDLARATVDDVQQNVQTAQNVNNVSDELHQTIKMFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=30.4843304843305, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI2367378, Length=268, Percent_Identity=35.0746268656716, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788195, Length=298, Percent_Identity=33.8926174496644, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788194, Length=314, Percent_Identity=31.8471337579618, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789453, Length=259, Percent_Identity=29.7297297297297, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68884; Mature: 68752

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKNKIMLTISGLICLTILVISTIGYFEFKSATTDDYRHNLSTKSFLVAKAVEGKMEAY
CCCCCEEEEEHHHHHHHHHHHHHHHCCCEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
FGALESISTSIHTDRSGNIMINPMLLKMMTNSKESLGVLNIYIGLPDGKTYDVKNQGIIP
HHHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCC
NFNAKQKQREWFNLGFSGAKRSVTNPYLATTGHLTMSVVIPFKARGETKAVIGLSLKMSD
CCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEEEEEECCCCCEEEEEEEEEHHH
ITDYINELSDVPNLFVSRQDGFLVAASYEDFIGKNIYDLRPSYREHGSKMTSEHSYNVPD
HHHHHHHHHHCCHHHEECCCCEEEEECCHHHHCCCHHHCCCCHHHHCCCCCCCCCCCCCC
KGDFYVVSSQIESLGWNIWAWASWDDIEAPSNAMVKINTVVGLIFAIMATGITFLLVTRL
CCCEEEEECHHHHCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MYRPIGGEPQYIEALVSRISAGDLTNIPKLNGDETGIYRSTLEMAGNLQGIIGNIEQSSN
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCHHHCCC
SLSSQSSSLETSSNQLSTSSEEQMMQLEQVATAMNQMTATVAEVAQNAMQASSSSNEASL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SSQSGLETVGDMNQQISLLVTNIEQVQDSILGVEKETQNVGSILDVIRGIAEQTNLLALN
CHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEHH
AAIEAARAGEQGRGFAVVADEVRNLANKTQESTNEIQTMISSLQTQAKQSVELMVENAET
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AKVTREKSDQASQMLNTIQHEIGTIQDMNNQIAAAAEEQSQVAVEINENVVNVNDLARAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCEECHHHHHHHH
VDDVQQNVQTAQNVNNVSDELHQTIKMFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVKNKIMLTISGLICLTILVISTIGYFEFKSATTDDYRHNLSTKSFLVAKAVEGKMEAY
CCCCEEEEEHHHHHHHHHHHHHHHCCCEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
FGALESISTSIHTDRSGNIMINPMLLKMMTNSKESLGVLNIYIGLPDGKTYDVKNQGIIP
HHHHHHHHHHHCCCCCCCEEECHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCC
NFNAKQKQREWFNLGFSGAKRSVTNPYLATTGHLTMSVVIPFKARGETKAVIGLSLKMSD
CCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEEEEEECCCCCEEEEEEEEEHHH
ITDYINELSDVPNLFVSRQDGFLVAASYEDFIGKNIYDLRPSYREHGSKMTSEHSYNVPD
HHHHHHHHHHCCHHHEECCCCEEEEECCHHHHCCCHHHCCCCHHHHCCCCCCCCCCCCCC
KGDFYVVSSQIESLGWNIWAWASWDDIEAPSNAMVKINTVVGLIFAIMATGITFLLVTRL
CCCEEEEECHHHHCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MYRPIGGEPQYIEALVSRISAGDLTNIPKLNGDETGIYRSTLEMAGNLQGIIGNIEQSSN
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCHHHCCC
SLSSQSSSLETSSNQLSTSSEEQMMQLEQVATAMNQMTATVAEVAQNAMQASSSSNEASL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SSQSGLETVGDMNQQISLLVTNIEQVQDSILGVEKETQNVGSILDVIRGIAEQTNLLALN
CHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEHH
AAIEAARAGEQGRGFAVVADEVRNLANKTQESTNEIQTMISSLQTQAKQSVELMVENAET
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AKVTREKSDQASQMLNTIQHEIGTIQDMNNQIAAAAEEQSQVAVEINENVVNVNDLARAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCEECHHHHHHHH
VDDVQQNVQTAQNVNNVSDELHQTIKMFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]