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The map label for this gene is moaE [H]

Identifier: 218708983

GI number: 218708983

Start: 1020928

End: 1021401

Strand: Direct

Name: moaE [H]

Synonym: VS_0989

Alternate gene names: 218708983

Gene position: 1020928-1021401 (Clockwise)

Preceding gene: 218708982

Following gene: 218708984

Centisome position: 30.94

GC content: 48.31

Gene sequence:

>474_bases
ATGAACGACTCTCGAGTTATTGATCCAAGAGTACTAGTTATGGCAGAAGATTTTTCTGTGGGTGACGAATACGATTATCT
AGCTCAAGGCACAGCTGCAGGAGCGGTAGTGACGTTTGTTGGTAAAGTTCGCGACATGAACCTTGGCGACAACGTGATTG
GTTTGTCTCTAGAGCACTATCCGGGTATGACAGAGAAGTCGCTGAGCGAGATCTGTGATCAAGCTGAAGCGCGCTGGCCT
ATTCAGAAGATGCGAGTGATTCACCGTGTTGGTGACCTAGATATCGGTGACCAGATTGTTTACGTTGGTGTATCCAGTGC
GCACCGAGGGGCTGCCTTCGAAGCGTGCGAGTTTGTTATGGACTTCCTCAAAACCAAAGCGCCGTTTTGGAAAAAAGAAC
GTACCACTGAAACAACTCGCTGGGTTGATTCTCGCGATTCTGATACCAAAGCTGCAGAGCGCTGGAAAAAGTAA

Upstream 100 bases:

>100_bases
AACTTCTGGCTGCGCTTAACCAATCAATCGTACCTTTGACAACTGAAGTGAAAGACGGCGATGAAGTGGCTTTCTTCCCA
CCTGTTACTGGAGGTTAGCC

Downstream 100 bases:

>100_bases
ATTATCCCACATAATGTTTCGTCCTTAACGTGATAACGCATTTCAGGTTAGGACTTAGGTAATAAAGCCGACGTTGAACG
TCGGTTTTTTTGTGCGTGCA

Product: molybdenum cofactor biosynthesis protein E

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNDSRVIDPRVLVMAEDFSVGDEYDYLAQGTAAGAVVTFVGKVRDMNLGDNVIGLSLEHYPGMTEKSLSEICDQAEARWP
IQKMRVIHRVGDLDIGDQIVYVGVSSAHRGAAFEACEFVMDFLKTKAPFWKKERTTETTRWVDSRDSDTKAAERWKK

Sequences:

>Translated_157_residues
MNDSRVIDPRVLVMAEDFSVGDEYDYLAQGTAAGAVVTFVGKVRDMNLGDNVIGLSLEHYPGMTEKSLSEICDQAEARWP
IQKMRVIHRVGDLDIGDQIVYVGVSSAHRGAAFEACEFVMDFLKTKAPFWKKERTTETTRWVDSRDSDTKAAERWKK
>Mature_157_residues
MNDSRVIDPRVLVMAEDFSVGDEYDYLAQGTAAGAVVTFVGKVRDMNLGDNVIGLSLEHYPGMTEKSLSEICDQAEARWP
IQKMRVIHRVGDLDIGDQIVYVGVSSAHRGAAFEACEFVMDFLKTKAPFWKKERTTETTRWVDSRDSDTKAAERWKK

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=132, Percent_Identity=37.1212121212121, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1787003, Length=146, Percent_Identity=60.2739726027397, Blast_Score=196, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17509279, Length=110, Percent_Identity=38.1818181818182, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356259, Length=102, Percent_Identity=36.2745098039216, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17693; Mature: 17693

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSRVIDPRVLVMAEDFSVGDEYDYLAQGTAAGAVVTFVGKVRDMNLGDNVIGLSLEHY
CCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHC
PGMTEKSLSEICDQAEARWPIQKMRVIHRVGDLDIGDQIVYVGVSSAHRGAAFEACEFVM
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
DFLKTKAPFWKKERTTETTRWVDSRDSDTKAAERWKK
HHHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNDSRVIDPRVLVMAEDFSVGDEYDYLAQGTAAGAVVTFVGKVRDMNLGDNVIGLSLEHY
CCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHC
PGMTEKSLSEICDQAEARWPIQKMRVIHRVGDLDIGDQIVYVGVSSAHRGAAFEACEFVM
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
DFLKTKAPFWKKERTTETTRWVDSRDSDTKAAERWKK
HHHHHCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]