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The map label for this gene is csgA [H]

Identifier: 218708940

GI number: 218708940

Start: 971150

End: 971836

Strand: Reverse

Name: csgA [H]

Synonym: VS_0942

Alternate gene names: 218708940

Gene position: 971836-971150 (Counterclockwise)

Preceding gene: 218708945

Following gene: 218708939

Centisome position: 29.46

GC content: 44.25

Gene sequence:

>687_bases
ATGAGCGTTATTTTTATTACTGGAGCGAACCGCGGCATAGGCTTAAGTCTGACTCAACAATACTTGAAAGATAATCACAA
GGTGTACGCAACTTACCGTGACGCCTCTTCAGCAACAGAACTGCTCTCACTCGCAGAGCACAGTAGCAACCTGACCTGCA
TTCAATTAGAAATAACCGATTATCAAGCAGTAGAACAACTCCCCTCGCAAATAGAGTCGATTGATATCTTGATCAACAAC
GCTGGCTACTATGGCCCTAAAGGTTACGGTCTGGGTGATACCGATGTCGAAGAGTGGCGTCGTGTATTTGAAATCAACAC
AATTGCCCCATTGAAGCTTGTCGAGACTCTATTACCTCTTATAGAAAGTAGTGACGTCAAAAAGATCGCCTGTCTTTCGT
CTAGAGTGGGTAGCATGTCTGAAAACACATCAGGCGGAGGCTACATCTATCGTTCATCTAAAGCGGCTCTTAACTCAGTT
GTGAAGAGTTTAAGCAACGACTTGACCGATAATGGCTTTACAGTGTTAGCGTTACATCCTGGGTGGGTACAGACCGAAAT
GGGCGGACCTAATGCTCTTATTGATACAGAGACTTCAGCTAAAGGCCTTGTGACTGTAATAGAGTCATCGAATACTGAAG
TGAGTGGTCACTTCTTTAATTTCGATGGTAGCGAAATAGACTGGTAG

Upstream 100 bases:

>100_bases
GTAATGATTTTTGTAGGAATGCTAATGGCCAGTTGGTGGACCGTTGATTTTCTCGTGTTAAGCCATCAAACTTAACTAAT
TGAACTGAAAAGGAATCACC

Downstream 100 bases:

>100_bases
CGATCACATGGATCGTCGCGTTATCTCAAGCTTGCTCGTACGTTCAACACTTTTGTGTCTAACAATGGTGCTAGCTGGAT
GTTTCGATGACAGCCCACAG

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSVIFITGANRGIGLSLTQQYLKDNHKVYATYRDASSATELLSLAEHSSNLTCIQLEITDYQAVEQLPSQIESIDILINN
AGYYGPKGYGLGDTDVEEWRRVFEINTIAPLKLVETLLPLIESSDVKKIACLSSRVGSMSENTSGGGYIYRSSKAALNSV
VKSLSNDLTDNGFTVLALHPGWVQTEMGGPNALIDTETSAKGLVTVIESSNTEVSGHFFNFDGSEIDW

Sequences:

>Translated_228_residues
MSVIFITGANRGIGLSLTQQYLKDNHKVYATYRDASSATELLSLAEHSSNLTCIQLEITDYQAVEQLPSQIESIDILINN
AGYYGPKGYGLGDTDVEEWRRVFEINTIAPLKLVETLLPLIESSDVKKIACLSSRVGSMSENTSGGGYIYRSSKAALNSV
VKSLSNDLTDNGFTVLALHPGWVQTEMGGPNALIDTETSAKGLVTVIESSNTEVSGHFFNFDGSEIDW
>Mature_227_residues
SVIFITGANRGIGLSLTQQYLKDNHKVYATYRDASSATELLSLAEHSSNLTCIQLEITDYQAVEQLPSQIESIDILINNA
GYYGPKGYGLGDTDVEEWRRVFEINTIAPLKLVETLLPLIESSDVKKIACLSSRVGSMSENTSGGGYIYRSSKAALNSVV
KSLSNDLTDNGFTVLALHPGWVQTEMGGPNALIDTETSAKGLVTVIESSNTEVSGHFFNFDGSEIDW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=30.4123711340206, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=184, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558990, Length=245, Percent_Identity=32.6530612244898, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193207563, Length=242, Percent_Identity=32.6446280991736, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=31.8181818181818, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17559962, Length=245, Percent_Identity=34.2857142857143, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17559964, Length=242, Percent_Identity=33.8842975206612, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17558992, Length=243, Percent_Identity=34.156378600823, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17558996, Length=253, Percent_Identity=31.2252964426877, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI72001658, Length=240, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17542178, Length=239, Percent_Identity=31.3807531380753, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541382, Length=250, Percent_Identity=30.8, Blast_Score=93, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17532177, Length=239, Percent_Identity=29.7071129707113, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17558006, Length=216, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322779, Length=246, Percent_Identity=30.8943089430894, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640547, Length=248, Percent_Identity=34.2741935483871, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=30.1587301587302, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24766; Mature: 24635

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIFITGANRGIGLSLTQQYLKDNHKVYATYRDASSATELLSLAEHSSNLTCIQLEITD
CEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECC
YQAVEQLPSQIESIDILINNAGYYGPKGYGLGDTDVEEWRRVFEINTIAPLKLVETLLPL
HHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
IESSDVKKIACLSSRVGSMSENTSGGGYIYRSSKAALNSVVKSLSNDLTDNGFTVLALHP
HCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECC
GWVQTEMGGPNALIDTETSAKGLVTVIESSNTEVSGHFFNFDGSEIDW
CEEEECCCCCCEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SVIFITGANRGIGLSLTQQYLKDNHKVYATYRDASSATELLSLAEHSSNLTCIQLEITD
EEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECC
YQAVEQLPSQIESIDILINNAGYYGPKGYGLGDTDVEEWRRVFEINTIAPLKLVETLLPL
HHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
IESSDVKKIACLSSRVGSMSENTSGGGYIYRSSKAALNSVVKSLSNDLTDNGFTVLALHP
HCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEECC
GWVQTEMGGPNALIDTETSAKGLVTVIESSNTEVSGHFFNFDGSEIDW
CEEEECCCCCCEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]