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The map label for this gene is gapA [H]

Identifier: 218708930

GI number: 218708930

Start: 958678

End: 959781

Strand: Reverse

Name: gapA [H]

Synonym: VS_0932

Alternate gene names: 218708930

Gene position: 959781-958678 (Counterclockwise)

Preceding gene: 218708932

Following gene: 218708929

Centisome position: 29.09

GC content: 42.75

Gene sequence:

>1104_bases
TTGACATTAAACAAGTTAAGTCGGATTATCTATTGCAGATGTATACTGGATTCTGTAATTTTACTACCAGTTATCTTTAA
TCAGAAATTAAGTTGTGGAGCAACTACAATGACTATCAAAGTAGGTATTAACGGTTTTGGCCGTATCGGCCGTTTCGTAT
TCCGCGCAGCTCAAGAGCGTGCAGACATCGAAGTAGTAGGTATTAACGATCTAATCGACGTAGAGTACATGGCATACATG
CTTAAGTACGACTCAACTCACGGCCGTTTCAACGGTACTGTTGAAGTTGAAGGCGGTAACCTAATCGTTAACGGTAAAAC
TGTACGTGTTACAGCTGAGCGTAACCCAGAAGACCTTAAGTGGGATGCTATCGAAGTAGACGTAGTTGCTGAAGCAACTG
GTCTTTTCCTAACTGACGAGACTGCACGTAAGCACATCACTGCTGGCGCTAAGAAAGTAGTTCTTACTGGTCCTTCTAAA
GATGCAACTCCAATGTTCGTAATGGGCGTTAACCAAGCATCTTACGCTGGTCAAGACATCGTTTCTAACGCTTCTTGTAC
TACTAACTGTCTTGCACCTATCGCTAAAGTACTTAACGATAAGTGGGGCATTGAGTCTGGTCTTATGACTACAGTTCACG
CTACTACAGCAACTCAAAAAACTGTAGATGGCCCTTCTGCTAAAGACTGGCGCGGTGGCCGTGGTGCTTCTCAAAACATC
ATCCCATCTTCAACTGGTGCTGCTAAAGCTGTAGGCGTTGTTCTTCCAGAACTAAACGGCCTTCTAACTGGTATGGCTTT
CCGTGTACCAACTGCTAACGTATCTGTAGTTGACCTAACTGTTAACCTAAAAGAAGCTGCATCTTACGAAGAAATTTGTG
CTGCAATGAAAGAAGCTTCTGAAGGCGAAATGGCTGGCGTTCTTGGTTACACTGAAGACCAAGTAGTATCACAAGATTTC
ATCGGTGAAGTTCAAACTTCAGTATTCGATGCTAAAGCTGGTGTTGCTCTAACTGACAAATTCGTTAAAGTTGTATCTTG
GTACGACAACGAAATCGGTTACTCAAACAAAGTTCTAGACCTAATCGCTCACATCTCTAAGTAA

Upstream 100 bases:

>100_bases
ATTTAGAGGTATTTTACCCAACTGGAAGGGTACAGAGCCACTCGCAATGGTCAATTTTCAACCACTTACACCCAATTGTT
AAGAAAAGCGTCGCTTTTTT

Downstream 100 bases:

>100_bases
TTTCTTTTTAGAAATAGCTTTAGATAAGCATTAGCGAAGACTGTTTTGAGCAGACTTTGAAAAAGGCGACCTTAGTGTCG
CCTTTTTAATACCTGCTATC

Product: glyceraldehyde-3-phosphate dehydrogenase A

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTLNKLSRIIYCRCILDSVILLPVIFNQKLSCGATTMTIKVGINGFGRIGRFVFRAAQERADIEVVGINDLIDVEYMAYM
LKYDSTHGRFNGTVEVEGGNLIVNGKTVRVTAERNPEDLKWDAIEVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSK
DATPMFVMGVNQASYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNI
IPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSVVDLTVNLKEAASYEEICAAMKEASEGEMAGVLGYTEDQVVSQDF
IGEVQTSVFDAKAGVALTDKFVKVVSWYDNEIGYSNKVLDLIAHISK

Sequences:

>Translated_367_residues
MTLNKLSRIIYCRCILDSVILLPVIFNQKLSCGATTMTIKVGINGFGRIGRFVFRAAQERADIEVVGINDLIDVEYMAYM
LKYDSTHGRFNGTVEVEGGNLIVNGKTVRVTAERNPEDLKWDAIEVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSK
DATPMFVMGVNQASYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNI
IPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSVVDLTVNLKEAASYEEICAAMKEASEGEMAGVLGYTEDQVVSQDF
IGEVQTSVFDAKAGVALTDKFVKVVSWYDNEIGYSNKVLDLIAHISK
>Mature_366_residues
TLNKLSRIIYCRCILDSVILLPVIFNQKLSCGATTMTIKVGINGFGRIGRFVFRAAQERADIEVVGINDLIDVEYMAYML
KYDSTHGRFNGTVEVEGGNLIVNGKTVRVTAERNPEDLKWDAIEVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSKD
ATPMFVMGVNQASYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNII
PSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSVVDLTVNLKEAASYEEICAAMKEASEGEMAGVLGYTEDQVVSQDFI
GEVQTSVFDAKAGVALTDKFVKVVSWYDNEIGYSNKVLDLIAHISK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=61.5151515151515, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=59.3939393939394, Blast_Score=409, Evalue=1e-114,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=83.0815709969789, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=42.2492401215805, Blast_Score=257, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=60.4790419161677, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=60.4790419161677, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=59.5808383233533, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=58.9820359281437, Blast_Score=400, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=63.1419939577039, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=62.8398791540785, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=62.2356495468278, Blast_Score=426, Evalue=1e-120,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=62.1951219512195, Blast_Score=420, Evalue=1e-118,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=62.1951219512195, Blast_Score=420, Evalue=1e-118,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=62.1951219512195, Blast_Score=420, Evalue=1e-118,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=62.1951219512195, Blast_Score=420, Evalue=1e-118,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=57.6687116564417, Blast_Score=381, Evalue=1e-106,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 39328; Mature: 39197

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNKLSRIIYCRCILDSVILLPVIFNQKLSCGATTMTIKVGINGFGRIGRFVFRAAQER
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
ADIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVEGGNLIVNGKTVRVTAERNPEDLK
CCEEEEECCCHHHHHHHHHHHHCCCCCCEECCEEEEECCEEEECCEEEEEEECCCCCCCE
WDAIEVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSKDATPMFVMGVNQASYAGQDI
ECEEEEEEEEECCCEEEECHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCHHHCCHHH
VSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNI
HCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
IPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSVVDLTVNLKEAASYEEICAAMKEAS
CCCCCCCHHHHEEHHHHHHHHHHHHEEECCCCCEEEEEEEEEHHHHCCHHHHHHHHHHCC
EGEMAGVLGYTEDQVVSQDFIGEVQTSVFDAKAGVALTDKFVKVVSWYDNEIGYSNKVLD
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
LIAHISK
HHHHHCC
>Mature Secondary Structure 
TLNKLSRIIYCRCILDSVILLPVIFNQKLSCGATTMTIKVGINGFGRIGRFVFRAAQER
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
ADIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVEGGNLIVNGKTVRVTAERNPEDLK
CCEEEEECCCHHHHHHHHHHHHCCCCCCEECCEEEEECCEEEECCEEEEEEECCCCCCCE
WDAIEVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSKDATPMFVMGVNQASYAGQDI
ECEEEEEEEEECCCEEEECHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCHHHCCHHH
VSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNI
HCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
IPSSTGAAKAVGVVLPELNGLLTGMAFRVPTANVSVVDLTVNLKEAASYEEICAAMKEAS
CCCCCCCHHHHEEHHHHHHHHHHHHEEECCCCCEEEEEEEEEHHHHCCHHHHHHHHHHCC
EGEMAGVLGYTEDQVVSQDFIGEVQTSVFDAKAGVALTDKFVKVVSWYDNEIGYSNKVLD
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
LIAHISK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]