Click here to switch to the map view.

The map label for this gene is aqpZ [H]

Identifier: 218708917

GI number: 218708917

Start: 945036

End: 945725

Strand: Reverse

Name: aqpZ [H]

Synonym: VS_0919

Alternate gene names: 218708917

Gene position: 945725-945036 (Counterclockwise)

Preceding gene: 218708922

Following gene: 218708911

Centisome position: 28.66

GC content: 48.12

Gene sequence:

>690_bases
ATGAATAGGTATATTGCAGAAATGTTTGGTACATTTTGGTTGGTGTTAGGCGGTTGTGGTAGTGCCGTCTTAGCCGCGGC
TTTCCCTGATGTGGGAATTGGTCTACTCGGAGTTTCCCTCGCTTTTGGTTTAACCGTTCTCACCATGGCTTTTGCTATTG
GCCATATATCCGGCTGTCATCTCAACCCTGCTGTTACTATTGGACTTTGGAGCGGTGGTCGCTTTGATGCCAAAGATGTC
GCACCTTATATTATTGCCCAAGTGATTGGCGGTATTATCGCAGGTGGCGTGTTATTTGTGATTGCTTCAGGCCAAGCTGG
CTTTGATGCAGCTGCCTCTGGCTTTGCTTCCAATGGTTATGGTGAACACTCACCGGGCGGTTACTCACTTACCGCTGCAC
TCGTTTGTGAAGTGGTCATGACCATGGTGTTCCTATTCGTGATCATGGGCGCGACTGATTCGAAAGCACCTGCTGGATTT
GCTCCTATCGCAATTGGTCTCTGTTTAACCCTAATTCACCTTATCAGCATTCCTGTAACCAACACCTCAGTGAACCCCGC
TCGAAGCACTGGCGTGGCTATGTTTGTTGGTGATTGGGCTGTTTCTCAGTTATGGCTATTCTGGATTGCACCGATTATTG
GTGCCGTGATTGGCGCAATGATATACAAAGCGGTGAGAGGTTCAGATTAA

Upstream 100 bases:

>100_bases
CCAAAACACTCCCTTTCTGTCGCTTATATGCCCAAGATTTCACAAACTTGCGAAATCTAAACTATCTTGTTGATACTGGT
ACAGATTAATAAGGATCGTT

Downstream 100 bases:

>100_bases
GCTCAGAGAAGTGTTTTGGAATAAAAACCTTTGAGAAGCATAAAAGAAAAAGCCGCTTGGTGATGGTTCACCAAGCGGCT
TTTTTTAGATTTTATGACGA

Product: aquaporin Z

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNRYIAEMFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVTIGLWSGGRFDAKDV
APYIIAQVIGGIIAGGVLFVIASGQAGFDAAASGFASNGYGEHSPGGYSLTAALVCEVVMTMVFLFVIMGATDSKAPAGF
APIAIGLCLTLIHLISIPVTNTSVNPARSTGVAMFVGDWAVSQLWLFWIAPIIGAVIGAMIYKAVRGSD

Sequences:

>Translated_229_residues
MNRYIAEMFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVTIGLWSGGRFDAKDV
APYIIAQVIGGIIAGGVLFVIASGQAGFDAAASGFASNGYGEHSPGGYSLTAALVCEVVMTMVFLFVIMGATDSKAPAGF
APIAIGLCLTLIHLISIPVTNTSVNPARSTGVAMFVGDWAVSQLWLFWIAPIIGAVIGAMIYKAVRGSD
>Mature_229_residues
MNRYIAEMFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVTIGLWSGGRFDAKDV
APYIIAQVIGGIIAGGVLFVIASGQAGFDAAASGFASNGYGEHSPGGYSLTAALVCEVVMTMVFLFVIMGATDSKAPAGF
APIAIGLCLTLIHLISIPVTNTSVNPARSTGVAMFVGDWAVSQLWLFWIAPIIGAVIGAMIYKAVRGSD

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI37694062, Length=198, Percent_Identity=37.8787878787879, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI4502183, Length=219, Percent_Identity=34.703196347032, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI4502179, Length=222, Percent_Identity=31.981981981982, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI4755125, Length=203, Percent_Identity=33.9901477832512, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI4502181, Length=203, Percent_Identity=33.9901477832512, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI6912506, Length=221, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI86792455, Length=225, Percent_Identity=28.8888888888889, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI157266307, Length=245, Percent_Identity=29.3877551020408, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI45446752, Length=205, Percent_Identity=28.2926829268293, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4826645, Length=246, Percent_Identity=26.0162601626016, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787101, Length=208, Percent_Identity=75, Blast_Score=312, Evalue=1e-86,
Organism=Escherichia coli, GI1790362, Length=250, Percent_Identity=28.4, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71993722, Length=236, Percent_Identity=27.1186440677966, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558372, Length=207, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71992966, Length=234, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24652747, Length=230, Percent_Identity=34.3478260869565, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45551084, Length=230, Percent_Identity=34.3478260869565, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24652751, Length=191, Percent_Identity=35.0785340314136, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19922038, Length=191, Percent_Identity=35.0785340314136, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136672, Length=231, Percent_Identity=28.1385281385281, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550503, Length=230, Percent_Identity=27.8260869565217, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24762342, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24762346, Length=224, Percent_Identity=29.0178571428571, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24762348, Length=224, Percent_Identity=29.0178571428571, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130305, Length=224, Percent_Identity=29.0178571428571, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24762344, Length=224, Percent_Identity=29.0178571428571, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 23391; Mature: 23391

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYIAEMFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCH
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LNPAVTIGLWSGGRFDAKDVAPYIIAQVIGGIIAGGVLFVIASGQAGFDAAASGFASNGY
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCC
GEHSPGGYSLTAALVCEVVMTMVFLFVIMGATDSKAPAGFAPIAIGLCLTLIHLISIPVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
NTSVNPARSTGVAMFVGDWAVSQLWLFWIAPIIGAVIGAMIYKAVRGSD
CCCCCCCHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRYIAEMFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCH
CCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LNPAVTIGLWSGGRFDAKDVAPYIIAQVIGGIIAGGVLFVIASGQAGFDAAASGFASNGY
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCC
GEHSPGGYSLTAALVCEVVMTMVFLFVIMGATDSKAPAGFAPIAIGLCLTLIHLISIPVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
NTSVNPARSTGVAMFVGDWAVSQLWLFWIAPIIGAVIGAMIYKAVRGSD
CCCCCCCHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA