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The map label for this gene is minD [H]

Identifier: 218708882

GI number: 218708882

Start: 906711

End: 907523

Strand: Reverse

Name: minD [H]

Synonym: VS_0882

Alternate gene names: 218708882

Gene position: 907523-906711 (Counterclockwise)

Preceding gene: 218708883

Following gene: 218708881

Centisome position: 27.51

GC content: 45.26

Gene sequence:

>813_bases
ATGGCACGCATTATCGTTGTAACGTCAGGTAAAGGCGGGGTAGGTAAAACGACCTCCAGTGCAGCTATTGCCTCAGGCTT
AGCTTTAAAAGGGAAGAAAACCGCAGTTATCGACTTTGATATCGGTCTGCGTAACCTAGATTTAATCATGGGTTGTGAGC
GTCGTGTTGTGTACGACTTCGTTAACGTTATCAATGGCGAAGCGACACTGAACCAAGCGATGATCAAAGACAAGCGCACA
GAGAATCTATTCATTCTTCCGGCTTCTCAAACTCGTGATAAAGATGCACTAACAAAAGATGGTGTTCGTCGTGTATTTGA
TGAACTAGATGAAATGGGCTTTGATTTCATCATCTGTGATTCTCCTGCAGGTATCGAGCAAGGCGCTCTGATGGCGCTTT
ACTTTGCTGATGAAGCGATTGTTACAACTAACCCAGAAGTTTCTTCTGTACGCGATTCAGACCGTATTCTCGGTATTCTC
GATTCTAAGTCTCGTCGTTCAGAAGATGGCTTAGAACCAGTGAAAACGCACCTTTTACTGACTCGCTACAACCCAGCACG
TGTAACTCAAGGTGAGATGCTAAGTGTTGAAGACGTTGAAGAGATTCTTCACATCTCTCTACTGGGTGTCATCCCAGAGA
GTCAAGCAGTACTGAACGCGTCGAACAAGGGTGTTCCAGTTATTTTTGACGAAGCAACCGACGCAGGTATGGCTTACAAT
GATACTGTAGAACGACTACTGGGTAGCCAAGTGGACTTCCGTTTCTTAACGGAACAGAAGAAAGGCATCTTCAAAAGACT
GTTCGGGGGCTAA

Upstream 100 bases:

>100_bases
GAAAGCGAGTACTGGCAGAAGAAAACCATGTTCAGTATGGCAAACGATGTATTACACGTTGATGTCCTCGCAATATAAGA
GAAATAAAAAGGAAAACTAA

Downstream 100 bases:

>100_bases
TTCGCAATGTCATTACTAGAGTTTTTTAGACCACAAAAAAAGACAACCGCAAACCTAGCTAAAGAGCGTTTGCAGATCAT
TGTTGCCGAGCGACGCAGCC

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MARIIVVTSGKGGVGKTTSSAAIASGLALKGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEATLNQAMIKDKRT
ENLFILPASQTRDKDALTKDGVRRVFDELDEMGFDFIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGIL
DSKSRRSEDGLEPVKTHLLLTRYNPARVTQGEMLSVEDVEEILHISLLGVIPESQAVLNASNKGVPVIFDEATDAGMAYN
DTVERLLGSQVDFRFLTEQKKGIFKRLFGG

Sequences:

>Translated_270_residues
MARIIVVTSGKGGVGKTTSSAAIASGLALKGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEATLNQAMIKDKRT
ENLFILPASQTRDKDALTKDGVRRVFDELDEMGFDFIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGIL
DSKSRRSEDGLEPVKTHLLLTRYNPARVTQGEMLSVEDVEEILHISLLGVIPESQAVLNASNKGVPVIFDEATDAGMAYN
DTVERLLGSQVDFRFLTEQKKGIFKRLFGG
>Mature_269_residues
ARIIVVTSGKGGVGKTTSSAAIASGLALKGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEATLNQAMIKDKRTE
NLFILPASQTRDKDALTKDGVRRVFDELDEMGFDFIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGILD
SKSRRSEDGLEPVKTHLLLTRYNPARVTQGEMLSVEDVEEILHISLLGVIPESQAVLNASNKGVPVIFDEATDAGMAYND
TVERLLGSQVDFRFLTEQKKGIFKRLFGG

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=79.6296296296296, Blast_Score=437, Evalue=1e-124,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29489; Mature: 29358

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIIVVTSGKGGVGKTTSSAAIASGLALKGKKTAVIDFDIGLRNLDLIMGCERRVVYDF
CEEEEEEECCCCCCCCCCCHHHHHHCEEECCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVINGEATLNQAMIKDKRTENLFILPASQTRDKDALTKDGVRRVFDELDEMGFDFIICD
HHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
SPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGILDSKSRRSEDGLEPVKTHLLL
CCCCCCCCCEEEEEEECCEEEECCCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHEEEE
TRYNPARVTQGEMLSVEDVEEILHISLLGVIPESQAVLNASNKGVPVIFDEATDAGMAYN
EECCCCCCCCCCEECHHHHHHHHHHHHEECCCCCHHEEECCCCCCEEEEECCCCCCCCHH
DTVERLLGSQVDFRFLTEQKKGIFKRLFGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARIIVVTSGKGGVGKTTSSAAIASGLALKGKKTAVIDFDIGLRNLDLIMGCERRVVYDF
EEEEEEECCCCCCCCCCCHHHHHHCEEECCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVINGEATLNQAMIKDKRTENLFILPASQTRDKDALTKDGVRRVFDELDEMGFDFIICD
HHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
SPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGILDSKSRRSEDGLEPVKTHLLL
CCCCCCCCCEEEEEEECCEEEECCCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHEEEE
TRYNPARVTQGEMLSVEDVEEILHISLLGVIPESQAVLNASNKGVPVIFDEATDAGMAYN
EECCCCCCCCCCEECHHHHHHHHHHHHEECCCCCHHEEECCCCCCEEEEECCCCCCCCHH
DTVERLLGSQVDFRFLTEQKKGIFKRLFGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]