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The map label for this gene is ompR [H]

Identifier: 218708873

GI number: 218708873

Start: 896788

End: 897516

Strand: Direct

Name: ompR [H]

Synonym: VS_0873

Alternate gene names: 218708873

Gene position: 896788-897516 (Clockwise)

Preceding gene: 218708872

Following gene: 218708874

Centisome position: 27.18

GC content: 47.6

Gene sequence:

>729_bases
ATGCCAACAAATACTCGAATTCTCGTGGTGGATGATGATCAAGAAATCTGCGAGCTGCTGGAAGAGTACCTCACAAAATC
AGGTTTCGATGTCTCTTCTGTGGGAGACGGTGTTGAATTAGAAAACCACCTGCAAAACCAAGGTTATCCCGACCTGATTC
TGCTCGATGTGATGCTCCCCGGTGACGACGGTTTTACCTTGTGTCAGCGAGTACGAAAGCAATCCAATGTGCCTATCATT
ATGCTGACAGCGGTATCGGATGAAACCGATCAGATTATCGGCTTAGAAATTGGTGCAGATGATTACATCGCGAAGCCGTT
TAGTCCTCGTCAGTTAATGGCTCGAATCAAAGCGCTATTACGCCGTGTACAAGTGGTGGACGACAAGCCAAGTGATGCAT
TGCCAAAGCAGATTATTTTTGGTGATTGGACGCTCGATACGCTCGCGCACCGAATCTATCACAATGAAAGCTCAGAAGAG
ATGGACTTGTCGGGCAGTGACTTTTCTTTGTTGATGTTGTTCTTAACTCGTCCTAACGAAGTTCTCGACCGTGACACCAT
CTCTTTCGCTACCAGAGGCCGTGAAGCGCTGCCTTTTGAACGTGGCATTGACGTACAGCTTAGCCGCCTGAGAAGCCGAT
TGGGCGACAGTGGTAAATATCCTCACTACATCAAAACCATGCGCGGTAATGGCTACATTCTTGCTGTGCCGGTTCAGTAT
GAACATTGA

Upstream 100 bases:

>100_bases
TATCTGTTTGTTCGTCTAACTTTACAAACATGTCAATAATCAAATAATCGGCCAGCCTATACACTATGTGAATAAGTTGT
AAATTTAATAGGTTTGGGCG

Downstream 100 bases:

>100_bases
TAATCAAGTGCTGTTAATGAACACCTTGCCAATGAAGTATTTCCTATGAACTGGTTGAGTCGATTAAAACCAAACTCTTT
GGTCGCAAGAACCTTATTGT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPTNTRILVVDDDQEICELLEEYLTKSGFDVSSVGDGVELENHLQNQGYPDLILLDVMLPGDDGFTLCQRVRKQSNVPII
MLTAVSDETDQIIGLEIGADDYIAKPFSPRQLMARIKALLRRVQVVDDKPSDALPKQIIFGDWTLDTLAHRIYHNESSEE
MDLSGSDFSLLMLFLTRPNEVLDRDTISFATRGREALPFERGIDVQLSRLRSRLGDSGKYPHYIKTMRGNGYILAVPVQY
EH

Sequences:

>Translated_242_residues
MPTNTRILVVDDDQEICELLEEYLTKSGFDVSSVGDGVELENHLQNQGYPDLILLDVMLPGDDGFTLCQRVRKQSNVPII
MLTAVSDETDQIIGLEIGADDYIAKPFSPRQLMARIKALLRRVQVVDDKPSDALPKQIIFGDWTLDTLAHRIYHNESSEE
MDLSGSDFSLLMLFLTRPNEVLDRDTISFATRGREALPFERGIDVQLSRLRSRLGDSGKYPHYIKTMRGNGYILAVPVQY
EH
>Mature_241_residues
PTNTRILVVDDDQEICELLEEYLTKSGFDVSSVGDGVELENHLQNQGYPDLILLDVMLPGDDGFTLCQRVRKQSNVPIIM
LTAVSDETDQIIGLEIGADDYIAKPFSPRQLMARIKALLRRVQVVDDKPSDALPKQIIFGDWTLDTLAHRIYHNESSEEM
DLSGSDFSLLMLFLTRPNEVLDRDTISFATRGREALPFERGIDVQLSRLRSRLGDSGKYPHYIKTMRGNGYILAVPVQYE
H

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=44.4915254237288, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.8260869565217, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=35.6828193832599, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=36.0515021459227, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=33.9130434782609, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=33.9055793991416, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=34.8360655737705, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=34.3347639484979, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=34.9344978165939, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.0175438596491, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=34.1991341991342, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=29.3103448275862, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=31.1688311688312, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790299, Length=102, Percent_Identity=34.3137254901961, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=30.5555555555556, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27386; Mature: 27254

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNTRILVVDDDQEICELLEEYLTKSGFDVSSVGDGVELENHLQNQGYPDLILLDVMLP
CCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHCCCCCCEEEEEEEEC
GDDGFTLCQRVRKQSNVPIIMLTAVSDETDQIIGLEIGADDYIAKPFSPRQLMARIKALL
CCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRVQVVDDKPSDALPKQIIFGDWTLDTLAHRIYHNESSEEMDLSGSDFSLLMLFLTRPNE
HHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHEEHEECCCCHH
VLDRDTISFATRGREALPFERGIDVQLSRLRSRLGDSGKYPHYIKTMRGNGYILAVPVQY
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEEE
EH
CC
>Mature Secondary Structure 
PTNTRILVVDDDQEICELLEEYLTKSGFDVSSVGDGVELENHLQNQGYPDLILLDVMLP
CCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHCCCCCCEEEEEEEEC
GDDGFTLCQRVRKQSNVPIIMLTAVSDETDQIIGLEIGADDYIAKPFSPRQLMARIKALL
CCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRVQVVDDKPSDALPKQIIFGDWTLDTLAHRIYHNESSEEMDLSGSDFSLLMLFLTRPNE
HHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHEEHEECCCCHH
VLDRDTISFATRGREALPFERGIDVQLSRLRSRLGDSGKYPHYIKTMRGNGYILAVPVQY
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEEEE
EH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]