Click here to switch to the map view.

The map label for this gene is hscB

Identifier: 218708632

GI number: 218708632

Start: 632691

End: 633206

Strand: Direct

Name: hscB

Synonym: VS_0610

Alternate gene names: 218708632

Gene position: 632691-633206 (Clockwise)

Preceding gene: 218708631

Following gene: 218708633

Centisome position: 19.18

GC content: 41.86

Gene sequence:

>516_bases
ATGAATCATTTCGAATTATTTGGGCTACCACTTCAGTTTCAACTGGATGGTAGCCTTCTTTCTTCTCAGTTTAGAGATCT
GCAACGCCAATTCCATCCTGATAAATTTGCGATAGCTTCTGAGCGTGACCGCTTATTAGCCGTGCAAAAAGCGGCACAAA
TCAACGATGCGTACCAGGTATTGAAGAATCCAATCAGCCGAGCAGAATACCTGTTGGTTCAACACGGAGAAGACATTCGT
GGTGAACAACAAACCATGCAAGATCCTATGTTCCTGATGGAGCAAATGGAACTGCGTGAAGAGCTGGAAGATATCGCAGA
CAGTTCTGATCCTGAAGATGCGCTATTTGCATTTGAAGGCAAGGTTAGCAAAATGTATAAACAACAATTAAGTGCTATCC
AACAAGAACTCGAAAGCGAAGCTTGGCTAGAAGCTGCAGACCGAGTAAGAAAGCTTAAGTTTATTGCAAAATTAAAGAAT
GAAATCGAATTAGTTGAAGATCGTTTGATCGGCTAG

Upstream 100 bases:

>100_bases
GTGAGAGCTTCAATGTTTAAACGCTTGAATCGTTAAGCGTTGTAAGCGAAGAATAAAATTAGGCTCTGAACAAAGAGCCT
AAACTTAGGACCACCTTTAC

Downstream 100 bases:

>100_bases
TTTGTATAACAAGGACACATCCATGGCACTACTTCAGATTGCAGAACCAGGGCAAAGCGCCGCTCCTCACCAGCAAAAGC
TTGCAGTGGGTATTGACTTA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNHFELFGLPLQFQLDGSLLSSQFRDLQRQFHPDKFAIASERDRLLAVQKAAQINDAYQVLKNPISRAEYLLVQHGEDIR
GEQQTMQDPMFLMEQMELREELEDIADSSDPEDALFAFEGKVSKMYKQQLSAIQQELESEAWLEAADRVRKLKFIAKLKN
EIELVEDRLIG

Sequences:

>Translated_171_residues
MNHFELFGLPLQFQLDGSLLSSQFRDLQRQFHPDKFAIASERDRLLAVQKAAQINDAYQVLKNPISRAEYLLVQHGEDIR
GEQQTMQDPMFLMEQMELREELEDIADSSDPEDALFAFEGKVSKMYKQQLSAIQQELESEAWLEAADRVRKLKFIAKLKN
EIELVEDRLIG
>Mature_171_residues
MNHFELFGLPLQFQLDGSLLSSQFRDLQRQFHPDKFAIASERDRLLAVQKAAQINDAYQVLKNPISRAEYLLVQHGEDIR
GEQQTMQDPMFLMEQMELREELEDIADSSDPEDALFAFEGKVSKMYKQQLSAIQQELESEAWLEAADRVRKLKFIAKLKN
EIELVEDRLIG

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=163, Percent_Identity=28.2208588957055, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788876, Length=170, Percent_Identity=49.4117647058824, Blast_Score=164, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17541320, Length=140, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI161084223, Length=171, Percent_Identity=29.2397660818713, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_VIBSL (B7VJS9)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416253.1
- ProteinModelPortal:   B7VJS9
- SMR:   B7VJS9
- GeneID:   7160230
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0610
- HOGENOM:   HBG751004
- OMA:   LNDAYQT
- ProtClustDB:   PRK05014
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19874; Mature: 19874

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHFELFGLPLQFQLDGSLLSSQFRDLQRQFHPDKFAIASERDRLLAVQKAAQINDAYQV
CCCCEEECCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNPISRAEYLLVQHGEDIRGEQQTMQDPMFLMEQMELREELEDIADSSDPEDALFAFEG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KVSKMYKQQLSAIQQELESEAWLEAADRVRKLKFIAKLKNEIELVEDRLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHFELFGLPLQFQLDGSLLSSQFRDLQRQFHPDKFAIASERDRLLAVQKAAQINDAYQV
CCCCEEECCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNPISRAEYLLVQHGEDIRGEQQTMQDPMFLMEQMELREELEDIADSSDPEDALFAFEG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KVSKMYKQQLSAIQQELESEAWLEAADRVRKLKFIAKLKNEIELVEDRLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA