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The map label for this gene is iscR

Identifier: 218708628

GI number: 218708628

Start: 630011

End: 630532

Strand: Direct

Name: iscR

Synonym: VS_0606

Alternate gene names: 218708628

Gene position: 630011-630532 (Clockwise)

Preceding gene: 218708627

Following gene: 218708629

Centisome position: 19.1

GC content: 44.06

Gene sequence:

>522_bases
ATGAAACTTACATCTAAAGGAAGATATGCGGTAACAGCTATGCTAGATGTAGCACTGCATTCGCAAAAAAGCCCAGTTCC
TCTGGCTGATATTTCAGAGCGACAAGGCATCTCGTTATCTTACTTAGAACAACTTTTTTCTAAGTTACGTAAAGCTGGCT
TGGTTGCTAGTGTTCGTGGTCCTGGCGGTGGTTACCGTTTAGGTGCTGAAGCGAGCGACATCGCTGTCGGAACTGTAATT
GCTGCAGTTGACGAATCAGTCGATGCAACTAAGTGTCACGGTCGAGCAGATTGCCAAGGTGGTACTCGTTGTTTAACTCA
CACTTTATGGCGTGATTTAAGCTCCCGAATCAGCAGCTTCTTAAACGACATTACGCTCGGTGAGCTAATGAAAGATAACG
AAGTTTTAGAGATTTCTGATCGTCAAGATATCGATCTTGCGGTTAATAATGGTTTTGCACATAAAAATACGAGCACTACA
ACGATTAGTGCAGCACCTCACGGTGTTAATGCCCGCTCTTAG

Upstream 100 bases:

>100_bases
AAGGGTGAATACCTGACTAAAATAGTCAACTAAATACTTGACCAATTTAGTCGGGTATGGGAAAATTCCAACCACATAAA
CAATGTGGATACGGTGTGAT

Downstream 100 bases:

>100_bases
CGGTCAGTTTTTACATTGGAGTAGAAAATGAAACTGCCTATTTACTTTGACTATTCAGCTACATGCCCAGTCGATCCACG
TGTTGCTGAAAAAATGGTTC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKLTSKGRYAVTAMLDVALHSQKSPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGAEASDIAVGTVI
AAVDESVDATKCHGRADCQGGTRCLTHTLWRDLSSRISSFLNDITLGELMKDNEVLEISDRQDIDLAVNNGFAHKNTSTT
TISAAPHGVNARS

Sequences:

>Translated_173_residues
MKLTSKGRYAVTAMLDVALHSQKSPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGAEASDIAVGTVI
AAVDESVDATKCHGRADCQGGTRCLTHTLWRDLSSRISSFLNDITLGELMKDNEVLEISDRQDIDLAVNNGFAHKNTSTT
TISAAPHGVNARS
>Mature_173_residues
MKLTSKGRYAVTAMLDVALHSQKSPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGAEASDIAVGTVI
AAVDESVDATKCHGRADCQGGTRCLTHTLWRDLSSRISSFLNDITLGELMKDNEVLEISDRQDIDLAVNNGFAHKNTSTT
TISAAPHGVNARS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788880, Length=142, Percent_Identity=76.056338028169, Blast_Score=207, Evalue=4e-55,
Organism=Escherichia coli, GI1790621, Length=143, Percent_Identity=27.972027972028, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): ISCR_VIBSL (B7VJS5)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416249.1
- ProteinModelPortal:   B7VJS5
- GeneID:   7160226
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0606
- HOGENOM:   HBG725923
- OMA:   QHISLSY
- HAMAP:   MF_01176
- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR02010
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 18427; Mature: 18427

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTSKGRYAVTAMLDVALHSQKSPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRG
CCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
PGGGYRLGAEASDIAVGTVIAAVDESVDATKCHGRADCQGGTRCLTHTLWRDLSSRISSF
CCCCEEECCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LNDITLGELMKDNEVLEISDRQDIDLAVNNGFAHKNTSTTTISAAPHGVNARS
HHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MKLTSKGRYAVTAMLDVALHSQKSPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRG
CCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECC
PGGGYRLGAEASDIAVGTVIAAVDESVDATKCHGRADCQGGTRCLTHTLWRDLSSRISSF
CCCCEEECCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LNDITLGELMKDNEVLEISDRQDIDLAVNNGFAHKNTSTTTISAAPHGVNARS
HHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA