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The map label for this gene is xerD [H]

Identifier: 218708546

GI number: 218708546

Start: 530772

End: 531734

Strand: Direct

Name: xerD [H]

Synonym: VS_0512

Alternate gene names: 218708546

Gene position: 530772-531734 (Clockwise)

Preceding gene: 218708544

Following gene: 218708547

Centisome position: 16.09

GC content: 47.25

Gene sequence:

>963_bases
TTGCTCTGGCATACTCTCAAAACAGTTTCCAATATTGTGAGTAACACTATGCAGTCGCCTCAAGGGCAGAGCGCAGACCA
CGGTCTAGTAGAACAGTTTTTAGATGCTATGTGGATGGAGCGAGGATTATCGGAGAATACGCTTGTCTCGTACCGTACCG
ACCTGTCTAAGCTTCTAACGTGGATGGAAAAGAACAATTACCGCCTCGATTTTATTAGTCTTTCAGGACTACAGGATTAT
CAAGGTTGGTTAGCCGATGCTGACTTTAAGCAGACTTCCCGCGCTCGTATGTTGTCGGCTATTCGTCGCTTGTTTCAATA
TCTACACCGCGAGAAAGTAAGAGCCGATGACCCTAGTGCATTGTTGATCAGTCCAAAACTGCCGAAGCGCTTGCCAAAAG
ATTTGAGTGAAGAGCAAGTGGATTCGCTGCTTGAAGCGCCAGATCCAAACGATCCAATCGAGCTTCGCGATAAGGCGATG
CTTGAGTTACTCTATGCAACTGGTCTGCGTGTTACGGAACTCGTCAGTTTGACGATGGAAAACATCAGCCTAAGACAGGG
CGTGGTGCGTGTTATTGGTAAGGGCGGTAAAGAACGCTTGGTGCCAATGGGCGAAAACGCCGTCGATTGGATAGAAACTT
TTATTGAACAAGGTCGCCCACAACTGCTCGGTGATAACAGCTCAGATGTGGTTTTTCCGAGTAAACGCGCGAAGCAAATG
ACTCGTCAAACGTTCTGGTATCGCATTAAGCATTATTCGGTGATAGCGGGTATCGACACGGAATTATTGTCTCCACACGT
ATTGAGACATGCTTTTGCCACTCATTTACTGAACTATGGCGCCGATCTCAGGGTCGTACAGATGTTGCTTGGACATAGTG
ACTTATCGACCACCCAAATTTATACTCACGTGGCGACTGAAAGGCTGAAGCAAATTCACGCTCAGCATCACCCACGTGCT
TAA

Upstream 100 bases:

>100_bases
CAAACGTTCAATTTTAATTTCAGATGGCGAATTCTAACCATAAATCGACTTCGATTGCAGCGATTATCCGCTCAAGTCGT
AATTTTTATGGCATTCATAT

Downstream 100 bases:

>100_bases
ATCCATTTATTTTTAAGGTGAACCTAATGAGCGTATTACGCCGTCTTCCTCTACTAGCGCTTCCTCTCATGATTACTGCA
TGTAATGCATCAGAAGCGAA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLWHTLKTVSNIVSNTMQSPQGQSADHGLVEQFLDAMWMERGLSENTLVSYRTDLSKLLTWMEKNNYRLDFISLSGLQDY
QGWLADADFKQTSRARMLSAIRRLFQYLHREKVRADDPSALLISPKLPKRLPKDLSEEQVDSLLEAPDPNDPIELRDKAM
LELLYATGLRVTELVSLTMENISLRQGVVRVIGKGGKERLVPMGENAVDWIETFIEQGRPQLLGDNSSDVVFPSKRAKQM
TRQTFWYRIKHYSVIAGIDTELLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHAQHHPRA

Sequences:

>Translated_320_residues
MLWHTLKTVSNIVSNTMQSPQGQSADHGLVEQFLDAMWMERGLSENTLVSYRTDLSKLLTWMEKNNYRLDFISLSGLQDY
QGWLADADFKQTSRARMLSAIRRLFQYLHREKVRADDPSALLISPKLPKRLPKDLSEEQVDSLLEAPDPNDPIELRDKAM
LELLYATGLRVTELVSLTMENISLRQGVVRVIGKGGKERLVPMGENAVDWIETFIEQGRPQLLGDNSSDVVFPSKRAKQM
TRQTFWYRIKHYSVIAGIDTELLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHAQHHPRA
>Mature_320_residues
MLWHTLKTVSNIVSNTMQSPQGQSADHGLVEQFLDAMWMERGLSENTLVSYRTDLSKLLTWMEKNNYRLDFISLSGLQDY
QGWLADADFKQTSRARMLSAIRRLFQYLHREKVRADDPSALLISPKLPKRLPKDLSEEQVDSLLEAPDPNDPIELRDKAM
LELLYATGLRVTELVSLTMENISLRQGVVRVIGKGGKERLVPMGENAVDWIETFIEQGRPQLLGDNSSDVVFPSKRAKQM
TRQTFWYRIKHYSVIAGIDTELLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHAQHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=69.4915254237288, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1790244, Length=305, Percent_Identity=37.7049180327869, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=28.4023668639053, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790767, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36613; Mature: 36613

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWHTLKTVSNIVSNTMQSPQGQSADHGLVEQFLDAMWMERGLSENTLVSYRTDLSKLLT
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WMEKNNYRLDFISLSGLQDYQGWLADADFKQTSRARMLSAIRRLFQYLHREKVRADDPSA
HHHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LLISPKLPKRLPKDLSEEQVDSLLEAPDPNDPIELRDKAMLELLYATGLRVTELVSLTME
EEECCCCCHHCHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
NISLRQGVVRVIGKGGKERLVPMGENAVDWIETFIEQGRPQLLGDNSSDVVFPSKRAKQM
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCEECCCHHHHHH
TRQTFWYRIKHYSVIAGIDTELLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQI
HHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
YTHVATERLKQIHAQHHPRA
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLWHTLKTVSNIVSNTMQSPQGQSADHGLVEQFLDAMWMERGLSENTLVSYRTDLSKLLT
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WMEKNNYRLDFISLSGLQDYQGWLADADFKQTSRARMLSAIRRLFQYLHREKVRADDPSA
HHHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LLISPKLPKRLPKDLSEEQVDSLLEAPDPNDPIELRDKAMLELLYATGLRVTELVSLTME
EEECCCCCHHCHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
NISLRQGVVRVIGKGGKERLVPMGENAVDWIETFIEQGRPQLLGDNSSDVVFPSKRAKQM
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCEECCCHHHHHH
TRQTFWYRIKHYSVIAGIDTELLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQI
HHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
YTHVATERLKQIHAQHHPRA
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA