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The map label for this gene is dapB

Identifier: 218708496

GI number: 218708496

Start: 473401

End: 474210

Strand: Direct

Name: dapB

Synonym: VS_0460

Alternate gene names: 218708496

Gene position: 473401-474210 (Clockwise)

Preceding gene: 218708495

Following gene: 218708497

Centisome position: 14.35

GC content: 47.65

Gene sequence:

>810_bases
GTGGTAAGAATTGCAATTGCAGGAGCAGCTGGCCGTATGGGTCGTAACTTGGTGAAAGCCGCTCACCATAATTCAGAAGC
AAGCGTTGGTGCTGGTTCAGAACGTCCAGAATCATCTTTGGTCGGTGTTGACGTTGGCGAGTTATGCGGTGAAGGTCGTT
TTGATGTGGCTCTAGTCGATGACCTTTCGAAAGCGGTTGAAGAGTTTGACGTGATCGTCGACTTTACCGCACCTGTAAGC
ACATTAGCGAATATTGAACTTTGTAAGCGTCACGGTAAAAAACTGATCATCGGCACTACGGGTTTCTCTGAAGAAGAAAA
GCTGGTTATCGATGCGGCTTCAAAAGAGATGGCTATCGTAATGGCACCTAACTACAGCGTTGGTGTAAACCTGGTCTTTA
AGCTGCTAGAGAAGGCCGCTAAAGTGATGGGCGACTATTGTGATGTCGAGATCGTTGAGGCTCATCACCGTCATAAAGTC
GATGCACCGTCAGGTACTGCGATTGGTATGGGCGAAGCTATTGCGGGTGCGATGGGCAACGAGCTGAACGATGTAGCTGT
ATGGTCACGCGAAGGTATTACTGGTGAGCGTACTAAAGATGAGATTGGTTTCGCGACGATTCGTGCCGGTGACATTATTG
GTGAACACACCGCTATGTTTGCTGATATCGGTGAACGAGTGGAAATTACCCATAAAGCCACTGATAGAATGACCTTTGCT
AATGGCGCAATCAAGGCCGCGGTTTGGTTAAATGATAAACCAGCAGGCTTTTATACCATGACGGATGTGCTTGGTTTGAA
TGACCTGTAA

Upstream 100 bases:

>100_bases
CCTGAGTTTGAGATTGTTGTTAGTTTAAAGAGATTAATCGATTGAACGTTGCTGCAAGAGATAAGTGGCAACGGTAACCA
AAACAATGGAGATATTCGCA

Downstream 100 bases:

>100_bases
ATAGATATTTATGCGCTGGCAATTGCCGGCGCTTTCTTTATTTGGTACCTTTTCCTTAGTAATCTCCCTTCTACGATCTT
CCTTCTACTTTCTTCTTATC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MVRIAIAGAAGRMGRNLVKAAHHNSEASVGAGSERPESSLVGVDVGELCGEGRFDVALVDDLSKAVEEFDVIVDFTAPVS
TLANIELCKRHGKKLIIGTTGFSEEEKLVIDAASKEMAIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDVEIVEAHHRHKV
DAPSGTAIGMGEAIAGAMGNELNDVAVWSREGITGERTKDEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
NGAIKAAVWLNDKPAGFYTMTDVLGLNDL

Sequences:

>Translated_269_residues
MVRIAIAGAAGRMGRNLVKAAHHNSEASVGAGSERPESSLVGVDVGELCGEGRFDVALVDDLSKAVEEFDVIVDFTAPVS
TLANIELCKRHGKKLIIGTTGFSEEEKLVIDAASKEMAIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDVEIVEAHHRHKV
DAPSGTAIGMGEAIAGAMGNELNDVAVWSREGITGERTKDEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
NGAIKAAVWLNDKPAGFYTMTDVLGLNDL
>Mature_269_residues
MVRIAIAGAAGRMGRNLVKAAHHNSEASVGAGSERPESSLVGVDVGELCGEGRFDVALVDDLSKAVEEFDVIVDFTAPVS
TLANIELCKRHGKKLIIGTTGFSEEEKLVIDAASKEMAIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDVEIVEAHHRHKV
DAPSGTAIGMGEAIAGAMGNELNDVAVWSREGITGERTKDEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
NGAIKAAVWLNDKPAGFYTMTDVLGLNDL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=268, Percent_Identity=60.4477611940298, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_VIBSL (B7VJ13)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416117.1
- GeneID:   7160095
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0460
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28585; Mature: 28585

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIAIAGAAGRMGRNLVKAAHHNSEASVGAGSERPESSLVGVDVGELCGEGRFDVALVD
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHCCCCCEEEEHHH
DLSKAVEEFDVIVDFTAPVSTLANIELCKRHGKKLIIGTTGFSEEEKLVIDAASKEMAIV
HHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCEEEE
MAPNYSVGVNLVFKLLEKAAKVMGDYCDVEIVEAHHRHKVDAPSGTAIGMGEAIAGAMGN
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCEECCHHHHHHHHCC
ELNDVAVWSREGITGERTKDEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
CCCCEEEEECCCCCCCCCCHHCCEEEEEECCHHCHHHHHHHHCCCEEEEEECCCCCEEEE
NGAIKAAVWLNDKPAGFYTMTDVLGLNDL
CCCEEEEEEECCCCCCEEEHHHHHCCCCC
>Mature Secondary Structure
MVRIAIAGAAGRMGRNLVKAAHHNSEASVGAGSERPESSLVGVDVGELCGEGRFDVALVD
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCHHHHCCCCCEEEEHHH
DLSKAVEEFDVIVDFTAPVSTLANIELCKRHGKKLIIGTTGFSEEEKLVIDAASKEMAIV
HHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCEEEE
MAPNYSVGVNLVFKLLEKAAKVMGDYCDVEIVEAHHRHKVDAPSGTAIGMGEAIAGAMGN
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCEECCHHHHHHHHCC
ELNDVAVWSREGITGERTKDEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
CCCCEEEEECCCCCCCCCCHHCCEEEEEECCHHCHHHHHHHHCCCEEEEEECCCCCEEEE
NGAIKAAVWLNDKPAGFYTMTDVLGLNDL
CCCEEEEEEECCCCCCEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA