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The map label for this gene is srlR [H]

Identifier: 218708431

GI number: 218708431

Start: 398270

End: 399040

Strand: Direct

Name: srlR [H]

Synonym: VS_0393

Alternate gene names: 218708431

Gene position: 398270-399040 (Clockwise)

Preceding gene: 218708427

Following gene: 218708432

Centisome position: 12.07

GC content: 45.4

Gene sequence:

>771_bases
ATGTCGAAACGAAACACCCAGCTCAGAAGACATGCAATTTCTAACCTAGTGAATGAAAAAGGGGAGGTTAGTGTTGATGA
ATTATCCGCTAAGTTCGAAACCTCAGAGGTCACGATTAGAAAGGACTTGGCGTCTTTAGAGAAAAACGGTCAGCTTTTGC
GCCGTTATGGTGGTGCGATTTCATTACCGAAAGAGGTTGTGAACGAAGAGCTGGGTCCACAAGTTTCGACTCGAAAGATT
TCATTAGCGAAAGCCGCGGCAGATTTAATTCGCGACCATAATCGCATTGTGATCGATAGCGGTAGCACGACAGGGGCGCT
AATTCAGCAGCTCAATAGCAAGCGTGGTTTGGTTGTGATGACCAACTCATTGCACGTTGCTAATGCACTTAATGAGTTGG
AAAGCGAACCAACACTGCTAATGACCGGCGGCACTTGGGATACCCATTCGGATTCTTTCCAAGGCAAAGTCGCAGAGTCA
GTACTTCGTGCTTACGATTTTGATCAACTATTTATTGGGGCTGATGGTATCGACCTTGATAGAGGAACAACCACGTTCAA
TGAATTGGTTGGTCTAAGTAAAGTAATGGCTGAAGTGTCACGAGAAGTGATCGTGATGGTTGAGTCGGAAAAGGTGGGAC
GAAAGATCCCGAACTTAGAGCTGGCATGGGAGCACATTGACATCTTAATTACCGATACAGACTTAGGCGAAGAATCCAAA
GCAAGTATCGAATCACATGATGTTCGTGTGATCTTGACTGATCCAGCGTAA

Upstream 100 bases:

>100_bases
TTATCGCTATTTATTAATTTTTTGGATCAAAATAAATGGACTAAATAGTTTCGTTGTAACTATAATATGTTTCACATCGA
AACTTAATGGCCTTTTTTAA

Downstream 100 bases:

>100_bases
AAACAAATTTAAGTATTATGCATTTACCTTCCTATAATTGATCTTGATAAAGATCTGGCCTTTGCTTGCTGCCAATAGGA
ATAAAACGAAATTGATGGAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSKRNTQLRRHAISNLVNEKGEVSVDELSAKFETSEVTIRKDLASLEKNGQLLRRYGGAISLPKEVVNEELGPQVSTRKI
SLAKAAADLIRDHNRIVIDSGSTTGALIQQLNSKRGLVVMTNSLHVANALNELESEPTLLMTGGTWDTHSDSFQGKVAES
VLRAYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMVESEKVGRKIPNLELAWEHIDILITDTDLGEESK
ASIESHDVRVILTDPA

Sequences:

>Translated_256_residues
MSKRNTQLRRHAISNLVNEKGEVSVDELSAKFETSEVTIRKDLASLEKNGQLLRRYGGAISLPKEVVNEELGPQVSTRKI
SLAKAAADLIRDHNRIVIDSGSTTGALIQQLNSKRGLVVMTNSLHVANALNELESEPTLLMTGGTWDTHSDSFQGKVAES
VLRAYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMVESEKVGRKIPNLELAWEHIDILITDTDLGEESK
ASIESHDVRVILTDPA
>Mature_255_residues
SKRNTQLRRHAISNLVNEKGEVSVDELSAKFETSEVTIRKDLASLEKNGQLLRRYGGAISLPKEVVNEELGPQVSTRKIS
LAKAAADLIRDHNRIVIDSGSTTGALIQQLNSKRGLVVMTNSLHVANALNELESEPTLLMTGGTWDTHSDSFQGKVAESV
LRAYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMVESEKVGRKIPNLELAWEHIDILITDTDLGEESKA
SIESHDVRVILTDPA

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=42.741935483871, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1789519, Length=255, Percent_Identity=39.2156862745098, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=31.7269076305221, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788069, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787540, Length=207, Percent_Identity=31.4009661835749, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789829, Length=213, Percent_Identity=30.9859154929577, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082344, Length=201, Percent_Identity=28.8557213930348, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28104; Mature: 27973

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRNTQLRRHAISNLVNEKGEVSVDELSAKFETSEVTIRKDLASLEKNGQLLRRYGGAI
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCC
SLPKEVVNEELGPQVSTRKISLAKAAADLIRDHNRIVIDSGSTTGALIQQLNSKRGLVVM
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEE
TNSLHVANALNELESEPTLLMTGGTWDTHSDSFQGKVAESVLRAYDFDQLFIGADGIDLD
ECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
RGTTTFNELVGLSKVMAEVSREVIVMVESEKVGRKIPNLELAWEHIDILITDTDLGEESK
CCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCEEEEEEEEEEEEECCCCCHHH
ASIESHDVRVILTDPA
CCCCCCCEEEEEECCC
>Mature Secondary Structure 
SKRNTQLRRHAISNLVNEKGEVSVDELSAKFETSEVTIRKDLASLEKNGQLLRRYGGAI
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCC
SLPKEVVNEELGPQVSTRKISLAKAAADLIRDHNRIVIDSGSTTGALIQQLNSKRGLVVM
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEE
TNSLHVANALNELESEPTLLMTGGTWDTHSDSFQGKVAESVLRAYDFDQLFIGADGIDLD
ECCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
RGTTTFNELVGLSKVMAEVSREVIVMVESEKVGRKIPNLELAWEHIDILITDTDLGEESK
CCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCEEEEEEEEEEEEECCCCCHHH
ASIESHDVRVILTDPA
CCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]