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The map label for this gene is orn [H]

Identifier: 218708317

GI number: 218708317

Start: 253740

End: 254285

Strand: Direct

Name: orn [H]

Synonym: VS_0255

Alternate gene names: 218708317

Gene position: 253740-254285 (Clockwise)

Preceding gene: 218708311

Following gene: 218708319

Centisome position: 7.69

GC content: 43.22

Gene sequence:

>546_bases
ATGTCCTTTAGCGATCAGAACCTTATTTGGGTTGATCTCGAGATGACAGGACTTGATCCTGAAACTCATAAAATCATTGA
AATTGCTACTATCGTTACTGATAGTGAGCTTAATATCCTGGCTGAAGGACCTGTTTTGGCTATTCACCAACCTCAGAGTG
AATTGGACAAGATGGACGAGTGGTGCACAACGACTCACACCGGCAGTGGCCTAGTGAAACGAATTCAAGACAGTACAGTT
TCAGAGCAAGATGCCATTCAACAAACGATTGAGTTTCTGGAAAAATGGGTACCAAAAGGTAAGTCACCAATTTGTGGCAA
CAGCATTGGTCAAGATCGCCGATTCTTATACAAGCATATGCCAGAGCTGGAAGAGTACTTCCACTACCGCTATGTTGATG
TTAGCACCCTGAAAGAGCTGACTCGCCGTTGGAAGCCTGAAGTGTTAGATGGTTTTTCTAAGTCGGGAAGCCACCTTGCA
TTAGACGATATTCGAGAGTCTATTGCTGAGCTGCAGTACTATCGAAAAACGATTATTAACATCTAA

Upstream 100 bases:

>100_bases
GTTGCTACTGCCATATGATTTCGATGGCTCTAAAGCTAGTTTGAGTATAGTTATTTGGGTATAGTACCTCTTTTATACAT
AAACAAATAGGCGACGCCTT

Downstream 100 bases:

>100_bases
TCAGATCAAATGTTCACGTTTATCTAACTTTTCAGGGACATAAGAGCTATTTTTTTTGCAAATATGTGTGCTTTTACAGC
AGTTGAGTAAAAACTTGCTG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSFSDQNLIWVDLEMTGLDPETHKIIEIATIVTDSELNILAEGPVLAIHQPQSELDKMDEWCTTTHTGSGLVKRIQDSTV
SEQDAIQQTIEFLEKWVPKGKSPICGNSIGQDRRFLYKHMPELEEYFHYRYVDVSTLKELTRRWKPEVLDGFSKSGSHLA
LDDIRESIAELQYYRKTIINI

Sequences:

>Translated_181_residues
MSFSDQNLIWVDLEMTGLDPETHKIIEIATIVTDSELNILAEGPVLAIHQPQSELDKMDEWCTTTHTGSGLVKRIQDSTV
SEQDAIQQTIEFLEKWVPKGKSPICGNSIGQDRRFLYKHMPELEEYFHYRYVDVSTLKELTRRWKPEVLDGFSKSGSHLA
LDDIRESIAELQYYRKTIINI
>Mature_180_residues
SFSDQNLIWVDLEMTGLDPETHKIIEIATIVTDSELNILAEGPVLAIHQPQSELDKMDEWCTTTHTGSGLVKRIQDSTVS
EQDAIQQTIEFLEKWVPKGKSPICGNSIGQDRRFLYKHMPELEEYFHYRYVDVSTLKELTRRWKPEVLDGFSKSGSHLAL
DDIRESIAELQYYRKTIINI

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=175, Percent_Identity=51.4285714285714, Blast_Score=188, Evalue=2e-48,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=67.4033149171271, Blast_Score=273, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI17557752, Length=175, Percent_Identity=50.2857142857143, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323088, Length=181, Percent_Identity=35.3591160220994, Blast_Score=115, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=49.4318181818182, Blast_Score=188, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20885; Mature: 20754

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSDQNLIWVDLEMTGLDPETHKIIEIATIVTDSELNILAEGPVLAIHQPQSELDKMDE
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHEEECCCCEEEECCCEEEEECCHHHHHHHHH
WCTTTHTGSGLVKRIQDSTVSEQDAIQQTIEFLEKWVPKGKSPICGNSIGQDRRFLYKHM
HHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
PELEEYFHYRYVDVSTLKELTRRWKPEVLDGFSKSGSHLALDDIRESIAELQYYRKTIIN
HHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure 
SFSDQNLIWVDLEMTGLDPETHKIIEIATIVTDSELNILAEGPVLAIHQPQSELDKMDE
CCCCCCEEEEEEEEECCCCCHHHHHHHHHEEECCCCEEEECCCEEEEECCHHHHHHHHH
WCTTTHTGSGLVKRIQDSTVSEQDAIQQTIEFLEKWVPKGKSPICGNSIGQDRRFLYKHM
HHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
PELEEYFHYRYVDVSTLKELTRRWKPEVLDGFSKSGSHLALDDIRESIAELQYYRKTIIN
HHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA