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The map label for this gene is yeeO [C]

Identifier: 218708298

GI number: 218708298

Start: 231686

End: 233116

Strand: Reverse

Name: yeeO [C]

Synonym: VS_0236

Alternate gene names: 218708298

Gene position: 233116-231686 (Counterclockwise)

Preceding gene: 218708304

Following gene: 218708286

Centisome position: 7.07

GC content: 47.38

Gene sequence:

>1431_bases
GTGAATTGTAAACTTTATGAAAGCGATCTTCAGACTATTCACAATTCACTGTACTCTACTCATATTCTAGTTCAATCGGC
GTTTTACATGCAAGATAAGCACGGGCTATTAGCCGCCCCTATTGAGAGTACATTGCGTACCATGACCATACCGACCATAT
TCGGTATGGTGGCGATCTTGATGTTTAACCTCGTCGATACTTTCTTTATCTCGTTGCTTGGTACTCAAGCCTTAGCAGCG
GTGAGCTTTACCTTTCCAGTCACCTTTGCCATTAACTGTATCACTATGGGGATTGGCATTGGCTTATCGACATGTATCGG
TCGGTTGCTTGGCCAAGGCAGCGCAAAAAATGCAGCTCGCTTTACCTGTCATGGTTTATTGCTGGCTTTGCTTCTGGTCG
GCTGCGCCTCTACGCTAGGTATTATCACCTTAGAACCACTGTTTACCCTGTTAGGGGCAAAGCAAGAGTTGTTACCACTG
ATATCGGAGTACATGTCGGTGTGGTATCTCGCGATCCCATTGTTGGTCATCCCCATGGCAGGCAACAGCGCGATTCGAGC
AACCGGTGATACAAAAACGCCCGCCAAAATCATGCTACTGGCTGGGCTTATCAATGGCGTGTTAGATCCGCTACTCATCT
TCGGATATGGGCCCTTCCCTGAACTGGGAATTCAAGGCGCAGCAATTGCCAGTGGTTTCAGTTGGTTTGGTGCTTTGTGT
GGCTCACTGTATGTGTTAACCATACGAGAAAAACTGCTTGCTCCTCCTAAGCTGCAAAACATCATCAATGACTGGCGACA
AATCCTAAAAATAGGAACACCAGCAGCTCTCTCCAATGCACTAAATCCACTTGCTGGCGCTATCATCATGATGATGTTAG
CCAAGCAAGGTACTGAAGCGGTAGCGGCGTATGGCGCTGCCCAGCGTATTGAATCCATTCTTATCATTGTGTTGATGTCT
CTGACTTCTGCTCTTACGCCTTTCATGGCGCAGAACTTTGGCGCAAACAACCCTCAACGCAGCTTCAAGGCTCTGTTTCT
CAGTATGCGCTTTGCTGTGATGTTCCAAGGGTTGGTCTTCTTGATGATGGTGCCACTGAGCATTCCTTTGGCAGCCCTAT
TCTCGCAAGAAGAATCAGTGCGAGGTGTGTTGTGGCACTACTTATTAGTCGTCCCGTTTAGCTATGGATTCCAAGGTATT
GTAATGATGCTGATCAGCGCCATGAATGCGATGCACCAACCACTCAAAGCCTTTCAATGGAGCTTCATGCGTTTGTTTGT
CTTTACCTTGCCTTTTGCGTGGATAGGCAGCCAAATTGATGGTGTCGAAGGACTGTTTATAGGCTTAGCTTTAGGGAACA
TTGTCGGCGGTGTTTCAGGGTATTGCTTTGCGCTTCGTGTTAGAGCTAAAGCTGATGCGGGATGCGAGTAA

Upstream 100 bases:

>100_bases
TATACGACTGTGGTTGTGTGGGCTGCTTCACTGTAAATCTCTCAAAATATCGAAATTGATAACGGCAGAATCCTATCACA
CCGCATACCGTTAGTAATGT

Downstream 100 bases:

>100_bases
TCGAGATGCGAAAAGATATAAGAGCAGATGCGAGATTCGAAGAGCTTGAGAACAGAAAGAGACTAGAAGAAGGAAGATGA
CATGGAAGACACCATTTACA

Product: multidrug efflux pump protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MNCKLYESDLQTIHNSLYSTHILVQSAFYMQDKHGLLAAPIESTLRTMTIPTIFGMVAILMFNLVDTFFISLLGTQALAA
VSFTFPVTFAINCITMGIGIGLSTCIGRLLGQGSAKNAARFTCHGLLLALLLVGCASTLGIITLEPLFTLLGAKQELLPL
ISEYMSVWYLAIPLLVIPMAGNSAIRATGDTKTPAKIMLLAGLINGVLDPLLIFGYGPFPELGIQGAAIASGFSWFGALC
GSLYVLTIREKLLAPPKLQNIINDWRQILKIGTPAALSNALNPLAGAIIMMMLAKQGTEAVAAYGAAQRIESILIIVLMS
LTSALTPFMAQNFGANNPQRSFKALFLSMRFAVMFQGLVFLMMVPLSIPLAALFSQEESVRGVLWHYLLVVPFSYGFQGI
VMMLISAMNAMHQPLKAFQWSFMRLFVFTLPFAWIGSQIDGVEGLFIGLALGNIVGGVSGYCFALRVRAKADAGCE

Sequences:

>Translated_476_residues
MNCKLYESDLQTIHNSLYSTHILVQSAFYMQDKHGLLAAPIESTLRTMTIPTIFGMVAILMFNLVDTFFISLLGTQALAA
VSFTFPVTFAINCITMGIGIGLSTCIGRLLGQGSAKNAARFTCHGLLLALLLVGCASTLGIITLEPLFTLLGAKQELLPL
ISEYMSVWYLAIPLLVIPMAGNSAIRATGDTKTPAKIMLLAGLINGVLDPLLIFGYGPFPELGIQGAAIASGFSWFGALC
GSLYVLTIREKLLAPPKLQNIINDWRQILKIGTPAALSNALNPLAGAIIMMMLAKQGTEAVAAYGAAQRIESILIIVLMS
LTSALTPFMAQNFGANNPQRSFKALFLSMRFAVMFQGLVFLMMVPLSIPLAALFSQEESVRGVLWHYLLVVPFSYGFQGI
VMMLISAMNAMHQPLKAFQWSFMRLFVFTLPFAWIGSQIDGVEGLFIGLALGNIVGGVSGYCFALRVRAKADAGCE
>Mature_476_residues
MNCKLYESDLQTIHNSLYSTHILVQSAFYMQDKHGLLAAPIESTLRTMTIPTIFGMVAILMFNLVDTFFISLLGTQALAA
VSFTFPVTFAINCITMGIGIGLSTCIGRLLGQGSAKNAARFTCHGLLLALLLVGCASTLGIITLEPLFTLLGAKQELLPL
ISEYMSVWYLAIPLLVIPMAGNSAIRATGDTKTPAKIMLLAGLINGVLDPLLIFGYGPFPELGIQGAAIASGFSWFGALC
GSLYVLTIREKLLAPPKLQNIINDWRQILKIGTPAALSNALNPLAGAIIMMMLAKQGTEAVAAYGAAQRIESILIIVLMS
LTSALTPFMAQNFGANNPQRSFKALFLSMRFAVMFQGLVFLMMVPLSIPLAALFSQEESVRGVLWHYLLVVPFSYGFQGI
VMMLISAMNAMHQPLKAFQWSFMRLFVFTLPFAWIGSQIDGVEGLFIGLALGNIVGGVSGYCFALRVRAKADAGCE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=347, Percent_Identity=23.342939481268, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51349; Mature: 51349

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCKLYESDLQTIHNSLYSTHILVQSAFYMQDKHGLLAAPIESTLRTMTIPTIFGMVAIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHH
MFNLVDTFFISLLGTQALAAVSFTFPVTFAINCITMGIGIGLSTCIGRLLGQGSAKNAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHH
FTCHGLLLALLLVGCASTLGIITLEPLFTLLGAKQELLPLISEYMSVWYLAIPLLVIPMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECC
GNSAIRATGDTKTPAKIMLLAGLINGVLDPLLIFGYGPFPELGIQGAAIASGFSWFGALC
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
GSLYVLTIREKLLAPPKLQNIINDWRQILKIGTPAALSNALNPLAGAIIMMMLAKQGTEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
VAAYGAAQRIESILIIVLMSLTSALTPFMAQNFGANNPQRSFKALFLSMRFAVMFQGLVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LMMVPLSIPLAALFSQEESVRGVLWHYLLVVPFSYGFQGIVMMLISAMNAMHQPLKAFQW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SFMRLFVFTLPFAWIGSQIDGVEGLFIGLALGNIVGGVSGYCFALRVRAKADAGCE
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MNCKLYESDLQTIHNSLYSTHILVQSAFYMQDKHGLLAAPIESTLRTMTIPTIFGMVAIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHH
MFNLVDTFFISLLGTQALAAVSFTFPVTFAINCITMGIGIGLSTCIGRLLGQGSAKNAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHH
FTCHGLLLALLLVGCASTLGIITLEPLFTLLGAKQELLPLISEYMSVWYLAIPLLVIPMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECC
GNSAIRATGDTKTPAKIMLLAGLINGVLDPLLIFGYGPFPELGIQGAAIASGFSWFGALC
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
GSLYVLTIREKLLAPPKLQNIINDWRQILKIGTPAALSNALNPLAGAIIMMMLAKQGTEA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
VAAYGAAQRIESILIIVLMSLTSALTPFMAQNFGANNPQRSFKALFLSMRFAVMFQGLVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LMMVPLSIPLAALFSQEESVRGVLWHYLLVVPFSYGFQGIVMMLISAMNAMHQPLKAFQW
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
SFMRLFVFTLPFAWIGSQIDGVEGLFIGLALGNIVGGVSGYCFALRVRAKADAGCE
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]