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The map label for this gene is gpmI

Identifier: 218708297

GI number: 218708297

Start: 229843

End: 231375

Strand: Direct

Name: gpmI

Synonym: VS_0235

Alternate gene names: 218708297

Gene position: 229843-231375 (Clockwise)

Preceding gene: 218708296

Following gene: 218708299

Centisome position: 6.97

GC content: 48.27

Gene sequence:

>1533_bases
ATGTCAGCTAAGAAGCCAATGGCTCTAGTGATCCTTGACGGTTACGGTTACCGTGAAGACAACCAAGACAACGCTATCGC
GAACGCTAAAACACCTGTATTAGACGGTCTTATTGCTAACCAACCTAACACGCTAATCTCAGCTTCTGGCTTAGATGTAG
GCCTACCTGATGGCCAAATGGGTAACTCTGAAGTGGGTCACACCAACATCGGTGCGGGTCGCGTGGTATACCAAGATTTA
ACGCGTATTACTAAATCAATCGCAGATGGCGAATTCGGTCAAACGGAAGCGCTAGTGAATGCTGTTGATAAAGCGGTTAA
AGTAGACAAAGCGGTTCACATCATGGGTCTTATGTCTCCAGGTGGCGTTCACTCTCATGAAGATCACATCTACGCAGCTG
TGGAAATGGCAGCAGCGCGTGGCGCAGAGAAAATCTACCTACACGCTTTCCTAGACGGTCGTGATACGCCGCCACGTAGT
GCAGAAAACACACTGGCACGTTTCCAAGAGCTATTCGCCAAATTGGGTAAAGGCCGTGTTGCTTCGCTTATTGGTCGTTA
CTACGCAATGGACCGTGATAACAACTGGGATCGCGTTCAAGAATCTTACGACCTGCTTACTCAAGCAAAAGCAGAGTTCA
CATTCGACACGGCAGTAGCTGGCCTAGAAGCGGCTTATGCTCGTGACGAAAACGATGAGTTCGTTAAAGCGACTGAAATT
AAAGCGGAAGGCGAAGAGTCTGCAGTTATCGTTGATGGCGATGCAGTTATCTTCATGAACTACCGTGCTGACCGTGCTCG
TGAAATCACACGTGCATTCGTTCCTGATTTCGATGGTTTTGCTCGTAACGTATTCCCAGCGATCGATTTCGTGATGCTGA
CTCAATATGCAGCAGACATCCCACTTCTATGTGCGTTCCCACCGGCTTCTCTAGAGAACACCTACGGTGAATGGCTATCG
AAAGAAGGCAAAACGCAGCTACGTATCTCTGAAACAGAGAAATACGCGCACGTGACGTTCTTCTTCAACGGCGGTAAAGA
AGACGAGTTTGAAGGCGAAGAGCGCCAACTTGTTGCTTCTCCAAAAGTCGCGACTTACGATCTACAGCCAGAAATGAGCG
CACCAGAACTTACTGAAAAGCTCGTTGCAGCAATCAAAGGTGGCAAATACGACGCTATTGTGTGTAACTTCCCTAACTGT
GACATGGTTGGCCACACTGGCGTTTACGATGCAGCGGTTAAAGCGGTAGAGTCGCTAGACGAATGTCTTGGCAAAGTGGT
TGAAGCAATCAAAGAAGCCGATGGCCAACTGCTTATCACCGCTGACCACGGTAACGCGGAAATGATGGTAAACCCAGAAA
CGGGCGGCATCCACACAGCGCACACTAACCTACCAGTGCCACTTATCTACGTAGGTAATAAAGACGTTGAGTTCAAAGAA
GGCGGTAAACTGTCTGACCTTGCACCAACGATGCTTTCTCTGTCTGGTATTGATATCCCAGTTGAAATGTCAGGTGACGT
GATCGTTAAGTAA

Upstream 100 bases:

>100_bases
GTTTCTTGATCTTCCACTACAGTTTTGACTGTAAACTGTAGTAAAATTACGCTAATTTGTTTTTATACCGATTTATTTTG
AATTGAACGAGGTCAGTCCT

Downstream 100 bases:

>100_bases
TTACTGTTTTTTTAGATAAATAGTTTTAACTTTCATCGAATATTAGAACGGCTGCGCGTGAGTGTAGCCGTTTTTTTGTA
TTTGGAATCTTATGTCTAGT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSAKKPMALVILDGYGYREDNQDNAIANAKTPVLDGLIANQPNTLISASGLDVGLPDGQMGNSEVGHTNIGAGRVVYQDL
TRITKSIADGEFGQTEALVNAVDKAVKVDKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHAFLDGRDTPPRS
AENTLARFQELFAKLGKGRVASLIGRYYAMDRDNNWDRVQESYDLLTQAKAEFTFDTAVAGLEAAYARDENDEFVKATEI
KAEGEESAVIVDGDAVIFMNYRADRAREITRAFVPDFDGFARNVFPAIDFVMLTQYAADIPLLCAFPPASLENTYGEWLS
KEGKTQLRISETEKYAHVTFFFNGGKEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKGGKYDAIVCNFPNC
DMVGHTGVYDAAVKAVESLDECLGKVVEAIKEADGQLLITADHGNAEMMVNPETGGIHTAHTNLPVPLIYVGNKDVEFKE
GGKLSDLAPTMLSLSGIDIPVEMSGDVIVK

Sequences:

>Translated_510_residues
MSAKKPMALVILDGYGYREDNQDNAIANAKTPVLDGLIANQPNTLISASGLDVGLPDGQMGNSEVGHTNIGAGRVVYQDL
TRITKSIADGEFGQTEALVNAVDKAVKVDKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHAFLDGRDTPPRS
AENTLARFQELFAKLGKGRVASLIGRYYAMDRDNNWDRVQESYDLLTQAKAEFTFDTAVAGLEAAYARDENDEFVKATEI
KAEGEESAVIVDGDAVIFMNYRADRAREITRAFVPDFDGFARNVFPAIDFVMLTQYAADIPLLCAFPPASLENTYGEWLS
KEGKTQLRISETEKYAHVTFFFNGGKEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKGGKYDAIVCNFPNC
DMVGHTGVYDAAVKAVESLDECLGKVVEAIKEADGQLLITADHGNAEMMVNPETGGIHTAHTNLPVPLIYVGNKDVEFKE
GGKLSDLAPTMLSLSGIDIPVEMSGDVIVK
>Mature_509_residues
SAKKPMALVILDGYGYREDNQDNAIANAKTPVLDGLIANQPNTLISASGLDVGLPDGQMGNSEVGHTNIGAGRVVYQDLT
RITKSIADGEFGQTEALVNAVDKAVKVDKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHAFLDGRDTPPRSA
ENTLARFQELFAKLGKGRVASLIGRYYAMDRDNNWDRVQESYDLLTQAKAEFTFDTAVAGLEAAYARDENDEFVKATEIK
AEGEESAVIVDGDAVIFMNYRADRAREITRAFVPDFDGFARNVFPAIDFVMLTQYAADIPLLCAFPPASLENTYGEWLSK
EGKTQLRISETEKYAHVTFFFNGGKEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKGGKYDAIVCNFPNCD
MVGHTGVYDAAVKAVESLDECLGKVVEAIKEADGQLLITADHGNAEMMVNPETGGIHTAHTNLPVPLIYVGNKDVEFKEG
GKLSDLAPTMLSLSGIDIPVEMSGDVIVK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=506, Percent_Identity=72.9249011857708, Blast_Score=762, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17507741, Length=517, Percent_Identity=47.0019342359768, Blast_Score=440, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI32564249, Length=517, Percent_Identity=47.0019342359768, Blast_Score=440, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_VIBSL (B7VHQ4)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002415918.1
- ProteinModelPortal:   B7VHQ4
- GeneID:   7159895
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0235
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- ProtClustDB:   PRK05434
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 55331; Mature: 55200

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKKPMALVILDGYGYREDNQDNAIANAKTPVLDGLIANQPNTLISASGLDVGLPDGQM
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCC
GNSEVGHTNIGAGRVVYQDLTRITKSIADGEFGQTEALVNAVDKAVKVDKAVHIMGLMSP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCC
GGVHSHEDHIYAAVEMAAARGAEKIYLHAFLDGRDTPPRSAENTLARFQELFAKLGKGRV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHH
ASLIGRYYAMDRDNNWDRVQESYDLLTQAKAEFTFDTAVAGLEAAYARDENDEFVKATEI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHCCCCCCCEEEEEEE
KAEGEESAVIVDGDAVIFMNYRADRAREITRAFVPDFDGFARNVFPAIDFVMLTQYAADI
ECCCCCCEEEEECCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
PLLCAFPPASLENTYGEWLSKEGKTQLRISETEKYAHVTFFFNGGKEDEFEGEERQLVAS
CEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEC
PKVATYDLQPEMSAPELTEKLVAAIKGGKYDAIVCNFPNCDMVGHTGVYDAAVKAVESLD
CCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ECLGKVVEAIKEADGQLLITADHGNAEMMVNPETGGIHTAHTNLPVPLIYVGNKDVEFKE
HHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCEEEEEECCCCCCCCC
GGKLSDLAPTMLSLSGIDIPVEMSGDVIVK
CCCCCHHHHHHHHHCCCCEEEECCCCEEEC
>Mature Secondary Structure 
SAKKPMALVILDGYGYREDNQDNAIANAKTPVLDGLIANQPNTLISASGLDVGLPDGQM
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCC
GNSEVGHTNIGAGRVVYQDLTRITKSIADGEFGQTEALVNAVDKAVKVDKAVHIMGLMSP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCC
GGVHSHEDHIYAAVEMAAARGAEKIYLHAFLDGRDTPPRSAENTLARFQELFAKLGKGRV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHH
ASLIGRYYAMDRDNNWDRVQESYDLLTQAKAEFTFDTAVAGLEAAYARDENDEFVKATEI
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHCCCCCCCEEEEEEE
KAEGEESAVIVDGDAVIFMNYRADRAREITRAFVPDFDGFARNVFPAIDFVMLTQYAADI
ECCCCCCEEEEECCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
PLLCAFPPASLENTYGEWLSKEGKTQLRISETEKYAHVTFFFNGGKEDEFEGEERQLVAS
CEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEC
PKVATYDLQPEMSAPELTEKLVAAIKGGKYDAIVCNFPNCDMVGHTGVYDAAVKAVESLD
CCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ECLGKVVEAIKEADGQLLITADHGNAEMMVNPETGGIHTAHTNLPVPLIYVGNKDVEFKE
HHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEECCCCEEEEEECCCCCCCCC
GGKLSDLAPTMLSLSGIDIPVEMSGDVIVK
CCCCCHHHHHHHHHCCCCEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA