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The map label for this gene is rfbC [H]

Identifier: 218708291

GI number: 218708291

Start: 223645

End: 224193

Strand: Direct

Name: rfbC [H]

Synonym: VS_0229

Alternate gene names: 218708291

Gene position: 223645-224193 (Clockwise)

Preceding gene: 218708290

Following gene: 218708292

Centisome position: 6.78

GC content: 39.16

Gene sequence:

>549_bases
ATGAAATTTATCGATACTGCTATTTCTGATGTGAAAATTGTTGAAGTGAGTGTATTTGGTGATGAACGAGGTTTCTTTAT
GGAAACATTTCGTGCAGATGAGTTTATGAAACAAACAGGTGCGAAGCCTTTTGTACAAGACAATCATAGTAAGTCAACGA
AAGGTATTTTACGCGGTTTGCATTTCCAGCAAGGACAAACACAAGGCAAGTTAGTACGTGTTACATCTGGTGCTGTTTAT
GATGTCGCTGTAGATATGCGCCAATCTTCGCCAACGTTTGGTAAAGCAGTAGGTGTGGAACTTTCTGCCGAGAATAAGCG
ACAATTATGGGTTCCAGAAGGTTTTGCTCACGGTTTCTATGTAATAACGGATTCTGCTGAATTCGTTTATAAGTGTACCG
ATTATTACCACCCTGAATCCGAAGTATCTGTTCGTTGGGATGATGTTGAACTTGCTATTGAGTGGCCATTAGTTGATGGT
GAACTACCTCAATTATCTGCAAAAGACGCAGATGCTTTCTCATTTAAAGATGCTCCAAAATTTGATTAA

Upstream 100 bases:

>100_bases
AAGGTTGGTTAAGTAAAGATGAACTACTTGTTCAAGCAGAAAAACTGAAGAAAACAGGTTACGGTCAGTACTTATTTAAT
ATCGCTAATGGAGTGATTTA

Downstream 100 bases:

>100_bases
TGGGTAAATCTCATATGAAAGTTGTTATTACAGGAAAAGGCGGTCAGCTTGCTTACGAGTTAGAGCAACTTGCTCCACAA
GGCGTTGAAGTTATTAGTGT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKFIDTAISDVKIVEVSVFGDERGFFMETFRADEFMKQTGAKPFVQDNHSKSTKGILRGLHFQQGQTQGKLVRVTSGAVY
DVAVDMRQSSPTFGKAVGVELSAENKRQLWVPEGFAHGFYVITDSAEFVYKCTDYYHPESEVSVRWDDVELAIEWPLVDG
ELPQLSAKDADAFSFKDAPKFD

Sequences:

>Translated_182_residues
MKFIDTAISDVKIVEVSVFGDERGFFMETFRADEFMKQTGAKPFVQDNHSKSTKGILRGLHFQQGQTQGKLVRVTSGAVY
DVAVDMRQSSPTFGKAVGVELSAENKRQLWVPEGFAHGFYVITDSAEFVYKCTDYYHPESEVSVRWDDVELAIEWPLVDG
ELPQLSAKDADAFSFKDAPKFD
>Mature_182_residues
MKFIDTAISDVKIVEVSVFGDERGFFMETFRADEFMKQTGAKPFVQDNHSKSTKGILRGLHFQQGQTQGKLVRVTSGAVY
DVAVDMRQSSPTFGKAVGVELSAENKRQLWVPEGFAHGFYVITDSAEFVYKCTDYYHPESEVSVRWDDVELAIEWPLVDG
ELPQLSAKDADAFSFKDAPKFD

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=183, Percent_Identity=54.6448087431694, Blast_Score=197, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=43.0232558139535, Blast_Score=142, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20477; Mature: 20477

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDTAISDVKIVEVSVFGDERGFFMETFRADEFMKQTGAKPFVQDNHSKSTKGILRGL
CCCHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCC
HFQQGQTQGKLVRVTSGAVYDVAVDMRQSSPTFGKAVGVELSAENKRQLWVPEGFAHGFY
CCCCCCCCCEEEEEECCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEE
VITDSAEFVYKCTDYYHPESEVSVRWDDVELAIEWPLVDGELPQLSAKDADAFSFKDAPK
EEECCCCEEEEECCCCCCCCCEEEEECCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
FD
CC
>Mature Secondary Structure
MKFIDTAISDVKIVEVSVFGDERGFFMETFRADEFMKQTGAKPFVQDNHSKSTKGILRGL
CCCHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCC
HFQQGQTQGKLVRVTSGAVYDVAVDMRQSSPTFGKAVGVELSAENKRQLWVPEGFAHGFY
CCCCCCCCCEEEEEECCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEE
VITDSAEFVYKCTDYYHPESEVSVRWDDVELAIEWPLVDGELPQLSAKDADAFSFKDAPK
EEECCCCEEEEECCCCCCCCCEEEEECCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
FD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]