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The map label for this gene is yabD [H]

Identifier: 218708170

GI number: 218708170

Start: 95574

End: 96335

Strand: Reverse

Name: yabD [H]

Synonym: VS_0104

Alternate gene names: 218708170

Gene position: 96335-95574 (Counterclockwise)

Preceding gene: 218708174

Following gene: 218708162

Centisome position: 2.92

GC content: 46.98

Gene sequence:

>762_bases
ATGATCGACACCCATGCTCATATTTACGCGAGCGAATTCGATGAAGACCGTGAACAAGTCGTGCAGCGCGCACTGGTTCA
AGGTATTGATACCATTCTATTGCCGAACATCGATTTAGCTTCTATCGAGCCCATGTTAGCGACGGAAGCTCAGTTTCCTG
ATGTGTGTCGTTCAATGATGGGCTTACACCCTTGTTATGTGGATGCGAATATCGAGCAGACCCTCAAAGCCATTCGAGCT
TGGTTTGATAAACATGACTTTATCGCCGTGGGTGAGATTGGTATCGACTTGTACTGGGATAAAACCTTCAAGGCTGAACA
AGAGATGGCTTTCGTGACTCAACTGCAGTGGGCAAAAGATCTAGACCTACCTGTCGTGATCCACACGCGTGATTCCATTG
AAGAGACACTTGCCCTGCTTCGCCAAGAACAAGACGGCAGCTTACGTGGCGTATTCCACTGCTTTGGCAGCAGCTTAGAG
GAGGCTCAAGCGATCAACGAGCTAGGCTTTCACTTAGGTTTAGGCGGTGTATCGACCTTTAAGAACTCAGGAATGGACAA
GGTGATTCCACATCTTGATATGAATTACGTCATTCTAGAGACAGATTGCCCATACTTGGCACCAACACCGAATCGCGGTA
AACGTAATGAGCCAGCCTACACGGAATTGGTAGCAAAACGCATCGCTGAATTGCGTGGAATGACCCTTGAAGAAGTCGAC
AATATAACGACCAGCAACGCTAAATTACTGTTTGGTTTATAA

Upstream 100 bases:

>100_bases
AACCCACTCAAAAACAGGGATAAATGGCAAAAAATGACCTTCTCCTCACACTGCCGTATACTCATGACAACTCAGTAAAG
ACTGCTTTCAGGACAAAATA

Downstream 100 bases:

>100_bases
TATCAATCGCAGTAAATCATCAGAAATAACGCAGTGATCGAGCTTTAAAACAAGTGAGCGTAACCCGTTATTTATGACGA
AGGTATAATCGACATTCGAT

Product: putative Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MIDTHAHIYASEFDEDREQVVQRALVQGIDTILLPNIDLASIEPMLATEAQFPDVCRSMMGLHPCYVDANIEQTLKAIRA
WFDKHDFIAVGEIGIDLYWDKTFKAEQEMAFVTQLQWAKDLDLPVVIHTRDSIEETLALLRQEQDGSLRGVFHCFGSSLE
EAQAINELGFHLGLGGVSTFKNSGMDKVIPHLDMNYVILETDCPYLAPTPNRGKRNEPAYTELVAKRIAELRGMTLEEVD
NITTSNAKLLFGL

Sequences:

>Translated_253_residues
MIDTHAHIYASEFDEDREQVVQRALVQGIDTILLPNIDLASIEPMLATEAQFPDVCRSMMGLHPCYVDANIEQTLKAIRA
WFDKHDFIAVGEIGIDLYWDKTFKAEQEMAFVTQLQWAKDLDLPVVIHTRDSIEETLALLRQEQDGSLRGVFHCFGSSLE
EAQAINELGFHLGLGGVSTFKNSGMDKVIPHLDMNYVILETDCPYLAPTPNRGKRNEPAYTELVAKRIAELRGMTLEEVD
NITTSNAKLLFGL
>Mature_253_residues
MIDTHAHIYASEFDEDREQVVQRALVQGIDTILLPNIDLASIEPMLATEAQFPDVCRSMMGLHPCYVDANIEQTLKAIRA
WFDKHDFIAVGEIGIDLYWDKTFKAEQEMAFVTQLQWAKDLDLPVVIHTRDSIEETLALLRQEQDGSLRGVFHCFGSSLE
EAQAINELGFHLGLGGVSTFKNSGMDKVIPHLDMNYVILETDCPYLAPTPNRGKRNEPAYTELVAKRIAELRGMTLEEVD
NITTSNAKLLFGL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=27.7153558052434, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=27.3408239700375, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226061614, Length=252, Percent_Identity=27.3809523809524, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI226061595, Length=232, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=31.3725490196078, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=32.4324324324324, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=30.078125, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=25.6227758007117, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=25.1908396946565, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=28.5046728971963, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648690, Length=290, Percent_Identity=24.4827586206897, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221330018, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24586117, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28468; Mature: 28468

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHAHIYASEFDEDREQVVQRALVQGIDTILLPNIDLASIEPMLATEAQFPDVCRSMM
CCCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCHHHCCHHHHCCCCCHHHHHHHH
GLHPCYVDANIEQTLKAIRAWFDKHDFIAVGEIGIDLYWDKTFKAEQEMAFVTQLQWAKD
CCCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHC
LDLPVVIHTRDSIEETLALLRQEQDGSLRGVFHCFGSSLEEAQAINELGFHLGLGGVSTF
CCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
KNSGMDKVIPHLDMNYVILETDCPYLAPTPNRGKRNEPAYTELVAKRIAELRGMTLEEVD
HCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
NITTSNAKLLFGL
CCCCCCCEEEEEC
>Mature Secondary Structure
MIDTHAHIYASEFDEDREQVVQRALVQGIDTILLPNIDLASIEPMLATEAQFPDVCRSMM
CCCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCHHHCCHHHHCCCCCHHHHHHHH
GLHPCYVDANIEQTLKAIRAWFDKHDFIAVGEIGIDLYWDKTFKAEQEMAFVTQLQWAKD
CCCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHC
LDLPVVIHTRDSIEETLALLRQEQDGSLRGVFHCFGSSLEEAQAINELGFHLGLGGVSTF
CCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
KNSGMDKVIPHLDMNYVILETDCPYLAPTPNRGKRNEPAYTELVAKRIAELRGMTLEEVD
HCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
NITTSNAKLLFGL
CCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]