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The map label for this gene is yedQ [H]

Identifier: 218705448

GI number: 218705448

Start: 2259916

End: 2261610

Strand: Reverse

Name: yedQ [H]

Synonym: ECUMN_2247

Alternate gene names: 218705448

Gene position: 2261610-2259916 (Counterclockwise)

Preceding gene: 218705449

Following gene: 218705445

Centisome position: 43.48

GC content: 51.92

Gene sequence:

>1695_bases
GTGCAGCACGAGACAAAAATGGAAAACCAGAGCTGGTTGAAAAAACTCGCACGCCGCCTGGGGCCTGGTCATGTCGTTAA
TCTCTGCTTTATCGTGGTATTGCTTTTTTCCACCTTGCTCACCTGGCGTGAAGTGGTGGTGCTGGAAGATGCCTATATCT
CCAGCCAGCGTAATCATCTGGAAAACGTAGCCAACGCGCTCGATAAGCATTTGCAGTATAACGTCGACAAACTGATCTTT
TTGCGTAATGGCATGCGCGAAGCTCTCGTAGCGCCACTGGATTTCACCTCTCTGCGTAATGCCGTAACCGAGTTCGAACA
GCATCGTGACGAGCACGCCTGGCAAATCGAACTCAACCGACGACGCACCCTGCCAGTCAATGGCGTGTCGGATGCATTAG
TCAGCGAGGGGAATCTCCTGTCTCGCGAAAATGAAAGCCTCGACAATGAAATTACCGCTGCACTGGAAGTTGGTTACTTG
CTGCGACTGGCGCACAACTCCTCGTCGATGGTTGAACAGGCGATGTATGTCTCGCGTGCCGGATTTTACGTTTCGACGCA
GCCGACCTTGTTTACGCGCAATGTACCAACGCGTTATTACGGCTATGTCACCCAACCCTGGTTTATCGGCCATTCGCAAC
GAGAAAATCGTCACCGCGCGGTACGCTGGTTCACATCGCAACCGGAACACGCCAGCAATACTGAACCGCAGGTTACCGTC
AGTGTTCCGGTAGACAGTGATAACTACTGGTATGGCGTGCTGGGGATGAGTATTCCCGTGCGTACCATGCAGCAATTTTT
AAGAAATGCCATCGATAAAAACCTCGATGGTGAGTATCAGCTCTATGACAGTAAGCTGAGATTATTGACCTCTTCCAATC
CTGACCATCCAACAGGGAATATTTTTGATCCTCGTGAACTGGCCTTGCTGGCGCAGGCAATGGAACATGACACACGGGGC
GGCATTCGTATGAACAGTCGTTATGTTAGCTGGGAACGTCTGGACCATTTCGACGGTGTGCTGGTGCGCGTCCATACGCT
AAGCGAAGGCGTGCGTGGTGATTTCGGCAGTATCAGCATTGCATTAACCCTGCTGTGGGCGCTCTTTACCACCATGTTAC
TCATCTCCTGGTATGTGATTCGCCGGATGGTCAGCAACATGTATGTTTTGCAAAGCTCGTTGCAGTGGCAGGCGTGGCAC
GACACCTTAACGCGTTTATATAACCGTGGCGCACTGTTCGAAAAAGCCCGTCCGCTCGCTAAATTGTGTCAGACGCACCA
ACATCCTTTTTCTGTCATTCAGGTCGACCTTGACCATTTTAAAGCGATTAATGACCGCTTTGGTCATCAGGCGGGCGACC
GTGTTCTTTCTCATGCTGCCGGATTAATTAGCAGTTCCTTGCGTGCGCAGGACGTTGCCGGGCGGGTCGGTGGTGAGGAG
TTTTGTGTGATTCTGCCAGGCGCGAGTCTGACGCAGGCTGCGGAGGTTGCAGAACGTATTCGCCTGAAGCTAAATGAAAA
AGAGATGTTGATCGCCAAGAGTACGACGATACGCATCAGTGCCTCGCTGGGGGTAAGCAGCAGCGAGGAAACCGGTGATT
ATGATTTTGAACAACTCCAGTCACTGGCCGACCGTCGACTTTATCTCGCTAAACAGGCCGGGCGCAATCGGGTATTCGCG
AGCGATAACGCTTAA

Upstream 100 bases:

>100_bases
GCGTCTTATCATGCCACCATTATAAAATTATCGCTGTTTTGCGGTACGTTATCGCCGGGTTATGCCAGAATCATAAAAAA
GCAGGTTGGGAGTCGTCAGG

Downstream 100 bases:

>100_bases
TGGGCGGAGAAAAAATGGTCCAGCCCTTCACGCCAGCCTTCCGGTCCTTCACGCTGCGTTCGCCAGACGCGGGCTGGATC
CTCATCATGCAGATGCACCC

Product: putative diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIF
LRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
LRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTV
SVPVDSDNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRLLTSSNPDHPTGNIFDPRELALLAQAMEHDTRG
GIRMNSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWH
DTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEE
FCVILPGASLTQAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFA
SDNA

Sequences:

>Translated_564_residues
MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIF
LRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
LRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTV
SVPVDSDNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRLLTSSNPDHPTGNIFDPRELALLAQAMEHDTRG
GIRMNSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWH
DTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEE
FCVILPGASLTQAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFA
SDNA
>Mature_564_residues
MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIF
LRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
LRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTV
SVPVDSDNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRLLTSSNPDHPTGNIFDPRELALLAQAMEHDTRG
GIRMNSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWH
DTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEE
FCVILPGASLTQAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFA
SDNA

Specific function: Involves in the regulation of cellulose production [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=564, Percent_Identity=98.936170212766, Blast_Score=1157, Evalue=0.0,
Organism=Escherichia coli, GI1787262, Length=246, Percent_Identity=30.8943089430894, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI145693134, Length=187, Percent_Identity=34.7593582887701, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788381, Length=165, Percent_Identity=35.1515151515151, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=35.4651162790698, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787802, Length=171, Percent_Identity=37.4269005847953, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=35.9756097560976, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87081974, Length=220, Percent_Identity=30, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788085, Length=190, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=164, Percent_Identity=32.3170731707317, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787056, Length=171, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787816, Length=130, Percent_Identity=35.3846153846154, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=33.7209302325581, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 64248; Mature: 64248

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHL
CCCCHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
ENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNR
HHHHHHHHHHHHCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
RRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRA
CCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTV
CEEEECCCEEEECCCCCHHEEEECCCEEECCCCCCCCHHHEEEECCCCCCCCCCCCEEEE
SVPVDSDNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRLLTSSNPDHPTGN
EEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHEEECCCCCCCCCC
IFDPRELALLAQAMEHDTRGGIRMNSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISI
CCCHHHHHHHHHHHHHCCCCCEEECCEEECHHHHHCCCCEEEEEEEHHCCCCCCCCHHHH
ALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCHHH
KLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEE
HHHHCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FCVILPGASLTQAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQ
EEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHH
SLADRRLYLAKQAGRNRVFASDNA
HHHHHHHHHHHHCCCCCEEECCCC
>Mature Secondary Structure
MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHL
CCCCHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHH
ENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNR
HHHHHHHHHHHHCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECC
RRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRA
CCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTV
CEEEECCCEEEECCCCCHHEEEECCCEEECCCCCCCCHHHEEEECCCCCCCCCCCCEEEE
SVPVDSDNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRLLTSSNPDHPTGN
EEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHEEECCCCCCCCCC
IFDPRELALLAQAMEHDTRGGIRMNSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISI
CCCHHHHHHHHHHHHHCCCCCEEECCEEECHHHHHCCCCEEEEEEEHHCCCCCCCCHHHH
ALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCHHH
KLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEE
HHHHCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FCVILPGASLTQAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQ
EEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHH
SLADRRLYLAKQAGRNRVFASDNA
HHHHHHHHHHHHCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]