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The map label for this gene is cheW [H]

Identifier: 218705387

GI number: 218705387

Start: 2207045

End: 2207548

Strand: Reverse

Name: cheW [H]

Synonym: ECUMN_2184

Alternate gene names: 218705387

Gene position: 2207548-2207045 (Counterclockwise)

Preceding gene: 218705388

Following gene: 218705386

Centisome position: 42.44

GC content: 51.79

Gene sequence:

>504_bases
ATGACCGGTATGACGAATGTAACAAAGCTGGCCAGCGAGCCGTCAGGCCAGGAATTTCTGGTATTTACCCTTGGTGATGA
AGAGTACGGTATTGATATCCTGAAAGTGCAGGAGATCCGTGGCTACGATCAGGTAACACGGATTGCGAACACGCCAGCGT
TTATCAAAGGCGTCACGAATCTGCGCGGCGTTATTGTGCCGATTGTCGACTTACGAATTAAGTTCAGCCAGGTGGATGTG
GACTATAACGACAACACGGTAGTTATCGTCCTGAATTTCGGACAGCGGGTGGTCGGCATCGTGGTTGACGGCGTTTCAGA
CGTGCTTTCATTGACGGCGGAGCAAATTCGTCCGGCACCGGAATTTGCCGTGACGCTTTCAACAGAATATCTCACTGGAC
TGGGCGCACTGGGCGACCGGATGTTGATTCTGGTGAACATCGAAAAACTGCTGAACAGCGAAGAGATGGCGCTGTTAGAT
AGCGCGGCGTCAGAAGTGGCGTAA

Upstream 100 bases:

>100_bases
GCAGCGTGGCACTGATTGTTGATGTCTCCGCCTTGCAGGCGATAAACCGCGAACAACGTATGGCGAACACCGCCGCCTGA
ATGAGTAAAAAGGTAACAAT

Downstream 100 bases:

>100_bases
TTCTCCCGATTTCCTCAATTGCAATGAACCCGATGACCTGCGCATCGGGTTTTTTATTTCAGTTTCGCGGCGGGTGGCAT
CAGCAATAAAGTTTCCCCCT

Product: purine-binding chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDV
DYNDNTVVIVLNFGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
SAASEVA

Sequences:

>Translated_167_residues
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDV
DYNDNTVVIVLNFGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
SAASEVA
>Mature_166_residues
TGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVD
YNDNTVVIVLNFGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDS
AASEVA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=167, Percent_Identity=99.4011976047904, Blast_Score=328, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18118; Mature: 17987

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCCCCHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCHHHHHHHCCCCHHHHHHCC
LRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNFGQRVVGIVVDGVSDVLSLTAEQIRPAP
CCEEEEEEEEEEEEEEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCC
EFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAASEVA
CEEEEEEHHHHHHHCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCCCHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCHHHHHHHCCCCHHHHHHCC
LRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNFGQRVVGIVVDGVSDVLSLTAEQIRPAP
CCEEEEEEEEEEEEEEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCC
EFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAASEVA
CEEEEEEHHHHHHHCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]