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The map label for this gene is cheR [H]

Identifier: 218705384

GI number: 218705384

Start: 2202713

End: 2203573

Strand: Reverse

Name: cheR [H]

Synonym: ECUMN_2181

Alternate gene names: 218705384

Gene position: 2203573-2202713 (Counterclockwise)

Preceding gene: 218705385

Following gene: 218705383

Centisome position: 42.36

GC content: 54.47

Gene sequence:

>861_bases
ATGACTTCATCTCTGCCCTGTGGGCAAACGTCTTTATTGTTACAGATGACCGAGCGCCTGGCGCTTTCCGACGCGCATTT
TCGGCGGATAAGTCAATTGATCTATCAACGAGCCGGGATCGTCCTGGCCGACCATAAACGCGACATGGTTTACAACCGAC
TGGTTCGTCGTTTGCGTTCGCTGGGACTGACGGATTTCGGCCATTACTTGAACTTGCTGGAATCTAACCAGCACAGCGGT
GAGTGGCAGGCGTTTATCAATTCGCTGACCACGAATCTGACGGCATTTTTCCGTGAGGCGCATCATTTTCCTCTGCTCGC
GGATCACGCCCGGCGTCGTTCTGGCGAGTATCGCGTATGGAGCGCGGCGGCTTCGACCGGCGAAGAGCCGTACAGCATTG
CGATGACACTGGCTGACACATTGGGCACCGCGCCCGGACGCTGGAAAGTGTTTGCCAGCGACATTGACACCGAAGTGCTG
GAAAAAGCCAGAAGCGGTATTTATCGCCATGAAGAGTTGAAAAACCTGACGCCGCAGCAACTGCAGCGGTACTTCATGCG
AGGGACGGGACCGCATCAAGGGCTGGTACGCGTGCGTCAGGAACTGGCGAATTATGTTGATTTTGCCCCGCTGAATTTAC
TGGCGAAACAGTACACCGTGCCGGGGCCGTTTGATGCGATCTTCTGTCGTAACGTCATGATCTACTTCGATCAAACTACC
CAGCAGGAGATTTTGCGCCGCTTTGTTCCGCTCCTTAAACCCGACGGATTGCTGTTTGCGGGTCACTCTGAAAACTTTAG
CCACCTTGAGCGCCGCTTCACGCTGCGTGGTCAGACGGTGTATGCGCTAAGTAAGGATTAA

Upstream 100 bases:

>100_bases
TGTGGCGGTATTTACCCTTGAAGAACATGAAGTAGCACGACATGAGTCGGCGCAGTTACAAATTGCGCCAGTGGTATCCT
GAAGTGATTGAGAAGGCGCT

Downstream 100 bases:

>100_bases
CGATGAGCAAAATCAGGGTGTTATCTGTCGATGATTCGGCACTGATGCGCCAGATCATGACAGAAATCATCAACAGCCAT
AGCGACATGGAAATGGTGGC

Product: chemotaxis methyltransferase CheR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSG
EWQAFINSLTTNLTAFFREAHHFPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHQGLVRVRQELANYVDFAPLNLLAKQYTVPGPFDAIFCRNVMIYFDQTT
QQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLRGQTVYALSKD

Sequences:

>Translated_286_residues
MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSG
EWQAFINSLTTNLTAFFREAHHFPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHQGLVRVRQELANYVDFAPLNLLAKQYTVPGPFDAIFCRNVMIYFDQTT
QQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLRGQTVYALSKD
>Mature_285_residues
TSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSGE
WQAFINSLTTNLTAFFREAHHFPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVLE
KARSGIYRHEELKNLTPQQLQRYFMRGTGPHQGLVRVRQELANYVDFAPLNLLAKQYTVPGPFDAIFCRNVMIYFDQTTQ
QEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLRGQTVYALSKD

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP [H]

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=286, Percent_Identity=99.6503496503496, Blast_Score=592, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 32849; Mature: 32718

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHH
LGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHHFPLLADHARRRSGEYRVW
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEE
SAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVLEKARSGIYRHEELKNLTPQQ
EHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHCCCHHH
LQRYFMRGTGPHQGLVRVRQELANYVDFAPLNLLAKQYTVPGPFDAIFCRNVMIYFDQTT
HHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCEEECCCH
QQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLRGQTVYALSKD
HHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
TSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHH
LGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHHFPLLADHARRRSGEYRVW
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEE
SAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVLEKARSGIYRHEELKNLTPQQ
EHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHCCCHHH
LQRYFMRGTGPHQGLVRVRQELANYVDFAPLNLLAKQYTVPGPFDAIFCRNVMIYFDQTT
HHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCEEECCCH
QQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLRGQTVYALSKD
HHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3510184; 9097040; 9278503 [H]