BacMap

Definition	Escherichia coli UMN026 chromosome, complete genome.
Accession	NC_011751
Length	5,202,090

Click here to switch to the map view.

The map label for this gene is yeaE [H]

Identifier: 218705279

GI number: 218705279

Start: 2097989

End: 2098843

Strand: Reverse

Name: yeaE [H]

Synonym: ECUMN_2070

Alternate gene names: 218705279

Gene position: 2098843-2097989 (Counterclockwise)

Preceding gene: 218705280

Following gene: 218705276

Centisome position: 40.35

GC content: 50.88

Gene sequence:

>855_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCACTGCCAGCCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGCAAAACAGAAGTAGCTGCACTACGCGCGGGCATTGAACTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGTGGTGCCGAAAAGGTGGTTGGGGAAGCATTAACCGGTCTGCGAGAGAAGGTCTTTCTCGTCTCTAAA
GTCTATCCGTGGAATGCTGGCGGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTACGCCGTCTCAATACTGATTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTCTCGAAGAGACTGTCGCAGCGATGGAAAAATTGGTCGCCCAGG
GCAAAATCCGCCGCTGGGGCGTTTCTAACCTTGATTATGCCGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTACTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTCCCTTGGTGCCAGCAACAGCA
GATACCGGTGATGGCTTACAGTCCGTTAGCTCAGGCCGGGCGGTTGCGCAATGGGCTGCTAAAAAACGCAGTAGTCAACG
AAATTGCACATGCTCACAATATCAGCTCGGCACAAGTATTGTTGGCGTGGGTAATCAGCCATCAGGGTGTGATGGCGATT
CCAAAAGCGGCCACGATTGCCCATGTCCAACAGAATGCGGCTGTGCTTGAGGTCGAACTTTCTCCAGCGGAATTAGCTAT
GCTGGATAAAGCGTATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATCTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTCACGCCCTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGGATGCATCGCACCCGGCACACAACATTAACGCAAATTAACGTTTGGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTTTCTT

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFALEETVAAMEKLVAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQIPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSPAELAMLDKAYPAPKGKTALDMV

Sequences:

>Translated_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFALEETVAAMEKLVAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQIPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSPAELAMLDKAYPAPKGKTALDMV
>Mature_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFALEETVAAMEKLVAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQIPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSPAELAMLDKAYPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=297, Percent_Identity=29.96632996633, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=31.3207547169811, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI24497577, Length=289, Percent_Identity=29.757785467128, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5174391, Length=289, Percent_Identity=29.757785467128, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI93277124, Length=301, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5174695, Length=302, Percent_Identity=28.476821192053, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI300116273, Length=288, Percent_Identity=29.5138888888889, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI310109922, Length=275, Percent_Identity=29.0909090909091, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI300116271, Length=280, Percent_Identity=27.1428571428571, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI310109920, Length=295, Percent_Identity=27.4576271186441, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI45446745, Length=295, Percent_Identity=27.4576271186441, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4503285, Length=295, Percent_Identity=27.4576271186441, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI5453543, Length=295, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=27.1477663230241, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI223718702, Length=182, Percent_Identity=32.4175824175824, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI41327764, Length=171, Percent_Identity=30.9941520467836, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=97.887323943662, Blast_Score=574, Evalue=1e-165,
Organism=Escherichia coli, GI87081735, Length=301, Percent_Identity=29.5681063122924, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786400, Length=249, Percent_Identity=30.1204819277108, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082198, Length=263, Percent_Identity=30.0380228136882, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=27.4760383386581, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=28.7749287749288, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=24.4582043343653, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI48994888, Length=237, Percent_Identity=32.0675105485232, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787674, Length=260, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561298, Length=276, Percent_Identity=31.8840579710145, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=31.0469314079422, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=28.3387622149837, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=29.96632996633, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=29.96632996633, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538386, Length=290, Percent_Identity=30, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561300, Length=293, Percent_Identity=29.0102389078498, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=25.752508361204, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550248, Length=297, Percent_Identity=25.2525252525253, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324694, Length=285, Percent_Identity=28.4210526315789, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320079, Length=291, Percent_Identity=28.1786941580756, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322556, Length=283, Percent_Identity=27.208480565371, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=309, Percent_Identity=24.9190938511327, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI221378297, Length=332, Percent_Identity=31.6265060240964, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=25.8620689655172, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24657054, Length=289, Percent_Identity=26.9896193771626, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=23.7458193979933, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129731, Length=297, Percent_Identity=26.5993265993266, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=26.984126984127, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356425, Length=298, Percent_Identity=24.496644295302, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=27.891156462585, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24662781, Length=289, Percent_Identity=27.3356401384083, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24662785, Length=291, Percent_Identity=27.1477663230241, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30961; Mature: 30961

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAL
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHH
EETVAAMEKLVAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQIPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEC
PKAATIAHVQQNAAVLEVELSPAELAMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAL
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHH
EETVAAMEKLVAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQIPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLAWVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEC
PKAATIAHVQQNAAVLEVELSPAELAMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]