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The map label for this gene is yneH [H]

Identifier: 218705008

GI number: 218705008

Start: 1821839

End: 1822765

Strand: Reverse

Name: yneH [H]

Synonym: ECUMN_1792

Alternate gene names: 218705008

Gene position: 1822765-1821839 (Counterclockwise)

Preceding gene: 218705009

Following gene: 218705007

Centisome position: 35.04

GC content: 51.67

Gene sequence:

>927_bases
GTGGCAGTCGCCATGGATAATGCAATTTTAGAAAACATCTTGCGGCAAGTACGGCCGCTCATTGGTCAGGGTAAAGTCGC
GAATTATATTCCGGCGCTGGCTACAGTAGACGGTTCCCGATTGGGCATTGCTATCTGTACCGTTGACGGACAGCTTTTTC
AGGCCGGAGACGCACAAGAACGTTTTTCCATTCAGTCTATTTCCAAAGTGCTGAGTCTCGTTGTCGCCATGCGTCATTAC
TCCGAAGAGGAAATCTGGCAACGCGTCGGCAAAGATCCGTCTGGATCACCGTTCAATTCTTTAGTGCAACTGGAAATGGA
GCAGGGTATTCCGCGTAATCCGTTTATTAATGCCGGTGCGCTGGTGGTCTGCGATATGTTGCAAGGGCGATTAAGCGCTC
CTCGGCAACGTATGCTGGAAGTCGTGCGCGGCTTAAGCGGTGTGTCTGATATTTCCTACGATACGGTGGTAGCGCGTTCC
GAATTTGAACACTCCGCGCGAAATGCGGCTATCGCCTGGCTGATGAAGTCGTTTGGCAATTTCCATCATGACGTGACAAC
CGTTCTGCAAAACTACTTTCATTACTGCGCTCTGAAAATGAGCTGTGTAGAGCTGGCCCGGACGTTTGTCTTTCTGGCTA
ATCAGGGGAAAGCTATTCATATTGATGAACCTGTGGTGACGCCAATGCAGGCGCGGCAAATTAATGCGCTGATGGCGACC
AGTGGTATGTACCAGAACGCGGGGGAGTTTGCCTGGCGGGTGGGACTACCGGCGAAATCTGGCGTTGGTGGCGGTATTGT
GGCGATTGTTCCGCATGAAATGGCCATCGCAGTCTGGAGTCCGGAACTGGATGATGCAGGTAACTCGCTCGCGGGTATCG
CCGTCCTTGAACAATTGACGAAACAGTTAGGGCGTTCGGTTTATTAA

Upstream 100 bases:

>100_bases
CTGTAATATCCAGACGGTGTGGAAAGACCGGATCTGACGCTACATATTCAGCTCTGATATACTCGCAGGTCTTTTCAGAC
CTGCGGTCCAGGAGTAGAAA

Downstream 100 bases:

>100_bases
TGCAGTCTCTCGATCCACTCTTCGCGCGTTTATTCCGTTCAAAATTTCGCTCTCGCTTTCGTTTGGGGGTGAAAGAGCGT
CAGTATTGTCTGGAGAAAGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAVAMDNAILENILRQVRPLIGQGKVANYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHY
SEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMAT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY

Sequences:

>Translated_308_residues
MAVAMDNAILENILRQVRPLIGQGKVANYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHY
SEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMAT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY
>Mature_307_residues
AVAMDNAILENILRQVRPLIGQGKVANYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYS
EEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARSE
FEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMATS
GMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=280, Percent_Identity=37.5, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=34.0136054421769, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=99.6753246753247, Blast_Score=633, Evalue=0.0,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=38.1118881118881, Blast_Score=195, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI193204073, Length=309, Percent_Identity=35.9223300970874, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193204075, Length=311, Percent_Identity=35.6913183279743, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17507019, Length=291, Percent_Identity=36.426116838488, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17532727, Length=304, Percent_Identity=33.2236842105263, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281363241, Length=294, Percent_Identity=35.0340136054422, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24653164, Length=294, Percent_Identity=35.0340136054422, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI281363239, Length=294, Percent_Identity=35.0340136054422, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24653162, Length=294, Percent_Identity=35.0340136054422, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=35.7894736842105, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24653156, Length=294, Percent_Identity=35.0340136054422, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=35.7894736842105, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=35.7894736842105, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33515; Mature: 33384

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAMDNAILENILRQVRPLIGQGKVANYIPALATVDGSRLGIAICTVDGQLFQAGDAQE
CCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCHHHCCCCHHH
RFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCH
LVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARSEFEHSARNAAIAWLMKSFGN
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHH
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLT
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHH
KQLGRSVY
HHHCCCCC
>Mature Secondary Structure 
AVAMDNAILENILRQVRPLIGQGKVANYIPALATVDGSRLGIAICTVDGQLFQAGDAQE
CEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCHHHCCCCHHH
RFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCH
LVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARSEFEHSARNAAIAWLMKSFGN
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHH
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLT
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHH
KQLGRSVY
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]