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The map label for this gene is yajO [H]

Identifier: 218704982

GI number: 218704982

Start: 1793914

End: 1794933

Strand: Reverse

Name: yajO [H]

Synonym: ECUMN_1766

Alternate gene names: 218704982

Gene position: 1794933-1793914 (Counterclockwise)

Preceding gene: 218704983

Following gene: 218704981

Centisome position: 34.5

GC content: 52.65

Gene sequence:

>1020_bases
ATGCAGTATACCCGGCTCGGTAAAAGTGACTTACTTGTTTCCCGCATCTGCATGGGATGCATGGGGTTTGGCGATCCGTC
GACGGGTCAGCATAGCTGGACGCTGGACGAAACAGCAAGCCGCGACATCATTCGCTATGGCCTTGAAAAGGGCATCAACT
TTTACGATACCGCTATAGCCTACCAGAATGGCTCCAGTGAGCGATACGTTGGCCGGGCATTACGGGAGATGGCGAAACGC
GATGATATCGTCCTGGCCACCAAGTTTCTGCCGCGAACCCCCGCACAAATTGCCGGAGGGATCAGCGGAAAAGAGGCAAT
CGCTCAATCCCTTGACCAGAGCCTGAAGAATCTGGGGATGGACTATATCGACCTCTACATCTACCACATCTGGGATTACA
ACACGCCCATTATCGACGTGCTTGAAGCGTTACATACCGCTGTTACTGCTGGCAAAGTACGAGCTGTTGGTATTTCAAAC
TGCTATGCCTGGCAGCTGGCGAAGGCGAACGCCCTTGCTGAACGCGAAGGGCTGACGCCCTTTGTTTCCGTACAGAGCCA
CTACAATCTAATTATGCGCGAAGATGAACGGGAGCTCTTCGGCCTGTGCACTGAGGATAATATCGCAATGACCCCCTATA
GCGCGCTGGCCAGCGGCCGCCTCTCTCGTAAAGAAGGCTATACACGGCGAGCCACAGAGGATGACTATGCGCGTGGAAAA
TATGACAGCACGGCTGAACAGGATCGCAGCATTATTGAGCGTGTAGCCGAACTGGCCGAACGCCATCTGGTGTCAATGAC
GGAAATATCTCTCGCTTGGCTGCTGACAAAAGTCACATCACCTGTCGTAGGGGCTACAAAAAAAGCTCATGTCGATGGCG
CGGTAAACGCAGTAAATCTTCAACTAAGTCCGGAGGAAATTCAGTTTCTGGAAGAAACCTACCAGCCGCATGTTCTGACG
GGGATCATGGCGCAAAATACGCCGCAAACGAAAGATGTTAAGCAGGTCTGGATGCGATAG

Upstream 100 bases:

>100_bases
CCGACAAAATCGCGCAGCAAAAAACGCTTGCCCGGGAACACGCTTCAAGGCTTGTCGAACTGCTCAATTCCGTCGTGAAT
AATCCAGAGGGAGAATAACA

Downstream 100 bases:

>100_bases
CCCTTATTCACTTTTCCTCCTCTCGTCTTTGAGAGCGCCAGTAGCGGTCGGTTACGTTCTTACCAGCACCAGTTGATCGA
ACGTCTTAAACAGTAATGTC

Product: putative Aryl-alcohol dehydrogenase (NADP(+))

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHSWTLDETASRDIIRYGLEKGINFYDTAIAYQNGSSERYVGRALREMAKR
DDIVLATKFLPRTPAQIAGGISGKEAIAQSLDQSLKNLGMDYIDLYIYHIWDYNTPIIDVLEALHTAVTAGKVRAVGISN
CYAWQLAKANALAEREGLTPFVSVQSHYNLIMREDERELFGLCTEDNIAMTPYSALASGRLSRKEGYTRRATEDDYARGK
YDSTAEQDRSIIERVAELAERHLVSMTEISLAWLLTKVTSPVVGATKKAHVDGAVNAVNLQLSPEEIQFLEETYQPHVLT
GIMAQNTPQTKDVKQVWMR

Sequences:

>Translated_339_residues
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHSWTLDETASRDIIRYGLEKGINFYDTAIAYQNGSSERYVGRALREMAKR
DDIVLATKFLPRTPAQIAGGISGKEAIAQSLDQSLKNLGMDYIDLYIYHIWDYNTPIIDVLEALHTAVTAGKVRAVGISN
CYAWQLAKANALAEREGLTPFVSVQSHYNLIMREDERELFGLCTEDNIAMTPYSALASGRLSRKEGYTRRATEDDYARGK
YDSTAEQDRSIIERVAELAERHLVSMTEISLAWLLTKVTSPVVGATKKAHVDGAVNAVNLQLSPEEIQFLEETYQPHVLT
GIMAQNTPQTKDVKQVWMR
>Mature_339_residues
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHSWTLDETASRDIIRYGLEKGINFYDTAIAYQNGSSERYVGRALREMAKR
DDIVLATKFLPRTPAQIAGGISGKEAIAQSLDQSLKNLGMDYIDLYIYHIWDYNTPIIDVLEALHTAVTAGKVRAVGISN
CYAWQLAKANALAEREGLTPFVSVQSHYNLIMREDERELFGLCTEDNIAMTPYSALASGRLSRKEGYTRRATEDDYARGK
YDSTAEQDRSIIERVAELAERHLVSMTEISLAWLLTKVTSPVVGATKKAHVDGAVNAVNLQLSPEEIQFLEETYQPHVLT
GIMAQNTPQTKDVKQVWMR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=299, Percent_Identity=29.7658862876254, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436962, Length=313, Percent_Identity=28.4345047923323, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI27436966, Length=313, Percent_Identity=28.4345047923323, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=28.343949044586, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=28.2051282051282, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436971, Length=320, Percent_Identity=28.125, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI41152114, Length=255, Percent_Identity=28.2352941176471, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI223718702, Length=194, Percent_Identity=29.8969072164948, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI41327764, Length=204, Percent_Identity=28.921568627451, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI223718708, Length=144, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=46.7692307692308, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=32.1981424148607, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=28.4431137724551, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=26.647564469914, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788081, Length=302, Percent_Identity=28.1456953642384, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17550248, Length=310, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561298, Length=307, Percent_Identity=24.7557003257329, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17566692, Length=303, Percent_Identity=24.4224422442244, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17552492, Length=301, Percent_Identity=24.2524916943522, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=34.9112426035503, Blast_Score=182, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6319958, Length=275, Percent_Identity=32.7272727272727, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323998, Length=312, Percent_Identity=30.7692307692308, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6319951, Length=275, Percent_Identity=30.5454545454545, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322615, Length=244, Percent_Identity=31.1475409836066, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320079, Length=255, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321052, Length=147, Percent_Identity=31.9727891156463, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24663317, Length=318, Percent_Identity=23.2704402515723, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37886; Mature: 37886

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHSWTLDETASRDIIRYGLEKGINFYDTAIA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCHHHHEEE
YQNGSSERYVGRALREMAKRDDIVLATKFLPRTPAQIAGGISGKEAIAQSLDQSLKNLGM
ECCCCCHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCC
DYIDLYIYHIWDYNTPIIDVLEALHTAVTAGKVRAVGISNCYAWQLAKANALAEREGLTP
HHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
FVSVQSHYNLIMREDERELFGLCTEDNIAMTPYSALASGRLSRKEGYTRRATEDDYARGK
EEEHHHHCCEEEECCCHHHHCCCCCCCEEECCHHHHHHCCCHHHCCCCCCCCCCHHHCCC
YDSTAEQDRSIIERVAELAERHLVSMTEISLAWLLTKVTSPVVGATKKAHVDGAVNAVNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHCCCCCCEEEEE
QLSPEEIQFLEETYQPHVLTGIMAQNTPQTKDVKQVWMR
EECHHHHHHHHHHCCCHHEEHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQYTRLGKSDLLVSRICMGCMGFGDPSTGQHSWTLDETASRDIIRYGLEKGINFYDTAIA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCHHHHEEE
YQNGSSERYVGRALREMAKRDDIVLATKFLPRTPAQIAGGISGKEAIAQSLDQSLKNLGM
ECCCCCHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCC
DYIDLYIYHIWDYNTPIIDVLEALHTAVTAGKVRAVGISNCYAWQLAKANALAEREGLTP
HHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
FVSVQSHYNLIMREDERELFGLCTEDNIAMTPYSALASGRLSRKEGYTRRATEDDYARGK
EEEHHHHCCEEEECCCHHHHCCCCCCCEEECCHHHHHHCCCHHHCCCCCCCCCCHHHCCC
YDSTAEQDRSIIERVAELAERHLVSMTEISLAWLLTKVTSPVVGATKKAHVDGAVNAVNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHCCCCCCEEEEE
QLSPEEIQFLEETYQPHVLTGIMAQNTPQTKDVKQVWMR
EECHHHHHHHHHHCCCHHEEHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]