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The map label for this gene is ddpA [H]

Identifier: 218704958

GI number: 218704958

Start: 1758887

End: 1760437

Strand: Reverse

Name: ddpA [H]

Synonym: ECUMN_1741

Alternate gene names: 218704958

Gene position: 1760437-1758887 (Counterclockwise)

Preceding gene: 218704959

Following gene: 218704957

Centisome position: 33.84

GC content: 50.1

Gene sequence:

>1551_bases
ATGAAGAGATCGATTTCGTTTCGTCCTACATTGCTCGCGATCGTCCTTGCCACAACAATGCCGGTTGCGCACGCCGCCGT
ACCGAAAGATATGCTGGTGATCGGTAAAGCTGCCGACCCACAAACCCTCGACCCAGCGGTGACAATTGATAATAACGACT
GGACAGTGACCTACCCGTCTTATCAGCGACTGGTTCAGTACAAAACGGACGGTGATAAAGGCTCAACCGACGTTGAAGGC
GATCTGGCGAGTAGCTGGAAAGCGTCTGACGATCAAAAAGAGTGGACATTCACCCTGAAGGATAATGCTAAATTTGCCGA
TGGCACTCCTGTCACTGCCGAAGCAGTAAAACTCTCTTTTGAGCGGTTACTAAAAATCGGCCAGGGGCCAGCAGAAGCAT
TTCCCAAAGATTTAAAGATTGATGCTCCCGACGAACATACAGTGAGGTTTACCCTTAGCCAGCCATTCGCACCGTTCCTC
TACACGCTGGCGAATGACGGTGCATCCATTATCAATCCGGCGGTCTTAAAGGAGCATGCGGCGGATGATGCCCGTGGTTT
CCTCGCGCAAAATACCGCTGGCTCCGGACCGTTTATGCTGAAAAGCTGGCAAAAAGGTCAGCAATTAGTTCTGGTGCCAA
ATCCGCATTACCCCGGCAATAAACCGAATTTCAAACGGGTATCGGTAAAAATTATCGGTGAAAGTGCTTCCCGTCGCCTG
CAGCTCTCCCGTGGCGACATTGACATTGCCGATGCGCTGCCGGTGGATCAACTCAACGCACTGAAGCAGGAAAACAAAGT
CAATGTGGCAGAGTATCCGTCACTGCGCGTCACCTATCTGTATCTGAATAACAGCAAAGCGCCACTTAATCAGGCGGATC
TGCGTCGGGCCATTTCCTGGTCTACCGATTATCAGGGTATGGTTAACGGCATTCTGAGTGGTAACGGAAAACAAATGCGC
GGCCCGATTCCGGAAGGCATGTGGGGATACGATGCGACGGCAATGCAATACAACCATGACGAAACGAAAGCCAAAGCCGA
ATGGGATAAAGTGACGAGCAAACCCACCAGCCTGACGTTTCTCTATTCTGATAATGATCCGAACTGGGAGCCTATTGCTC
TGGCGACACAATCCAGTCTCAACAAGCTGGGCATCAACGTGAAGCTGGAAAAGCTGGCGAACGCCACCATGCGCGACAGA
GTGGGAAAAGGTGATTATGACATTGCGATTGGCAACTGGAGTCCGGATTTTGCCGACCCGTATATGTTTATGAATTACTG
GTTTGAGTCAGACAAAAAAGGTCTGCCGGGTAACCGCTCGTTCTATGAAAACAGTGAGGTCGATAAGTTACTGCGCAATG
CGCTAGCGACCACCGACCAGACGCAGCGTACTCGGGACTACCAGCAGGCACAGAAAATCGTCATTGATGACGCTGCTTAT
GTGTACCTGTTCCAGAAAAACTACCAACTGGCGATGAACAAAGAGGTGAAAGGTTTTGTGTTCAATCCCATGCTGGAACA
GGTCTTCAATATCAATACCATGAGTAAATAA

Upstream 100 bases:

>100_bases
TTCGAATTACCCCAGGCAGCGAGTTACCCACTACTCGCTGATCAATTCACCTGTTTTATATCCCCTGGCACACAGCACGC
CAGTTAATCAGGAAACTGTC

Downstream 100 bases:

>100_bases
CGTGACCTTCTGGAGTATTTTACGCCAACGCTGCTGGGGGCTGGTGCTCGTGGTGGCGGGCGTCTGTGTGATAACGTTTA
TTATCTCGCACCTGATCCCC

Product: D-ala-D-a la ABC transporter periplasmic-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKRSISFRPTLLAIVLATTMPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVRFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK

Sequences:

>Translated_516_residues
MKRSISFRPTLLAIVLATTMPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVRFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
>Mature_516_residues
MKRSISFRPTLLAIVLATTMPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVRFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=516, Percent_Identity=99.031007751938, Blast_Score=1053, Evalue=0.0,
Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=26.5267175572519, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI87081878, Length=538, Percent_Identity=27.8810408921933, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1787052, Length=521, Percent_Identity=25.9117082533589, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1787495, Length=518, Percent_Identity=26.2548262548263, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789887, Length=526, Percent_Identity=25.2851711026616, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787551, Length=467, Percent_Identity=23.1263383297645, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=24.1965973534972, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57642; Mature: 57642

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSISFRPTLLAIVLATTMPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCC
YQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHEEEECCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVRFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCEE
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRSISFRPTLLAIVLATTMPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCC
YQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHEEEECCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVRFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCEE
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]